Cerebral oximetry in preterm infants: an agenda for research with a clear clinical goal

Gorm Greisen; Bjørn Andresen; Anne Mette Plomgaard; Simon Hyttel-Sørensen

doi:10.1117/1.NPh.3.3.031407

25 April 2016 Cerebral oximetry in preterm infants: an agenda for research with a clear clinical goal

Gorm Greisen, Bjørn Andresen, Anne Mette Plomgaard, Simon Hyttel-Sørensen

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Neurophotonics, Vol. 3, Issue 3, 031407 (April 2016). https://doi.org/10.1117/1.NPh.3.3.031407

Abstract

Preterm birth constitutes a major cause of death before 5 years of age and it is a major cause of neurodevelopmental impairment across the world. Preterm infants are most unstable during the transition between fetal and newborn life during the first days of life and most brain damage occurs in this period. The brain of the preterm infant is accessible for tissue oximetry by near-infrared spectroscopy. Cerebral oximetry has the potential to improve the long-term outcome by helping to tailor the support of respiration and circulation to the individual infant’s needs, but the evidence is still lacking. The goals for research include testing the benefit and harms of cerebral oximetry in large-scale randomized trials, improved definition of the hypoxic threshold, better understanding the effects of intensive care on cerebral oxygenation, as well as improved precision of oximeters and calibration among devices or standardization of values in the hypoxic range. These goals can be pursued in parallel.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Gorm Greisen, Bjørn Andresen, Anne Mette Plomgaard, and Simon Hyttel-Sørensen "Cerebral oximetry in preterm infants: an agenda for research with a clear clinical goal," Neurophotonics 3(3), 031407 (25 April 2016). https://doi.org/10.1117/1.NPh.3.3.031407

Published: 25 April 2016

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