1 April 1998 Charge-coupled device/fiber optic taper array x-ray detector for protein crystallography
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Abstract
A large area charge-coupled device (CCD) based fiber optic taper array detector (APS-1) is installed at the insertion-device beamline of the Structural Biology Center at the Argonne Advanced Photon Source x-ray synchrotron. The detector is used in protein crystallography diffraction experiments, where the objective is to measure the position and intensity of x-ray Bragg peaks in diffraction images. Large imaging area, very high spatial resolution, high x-ray sensitivity, good detective quantum efficiency, low noise, wide dynamic range, excellent stability and short readout time are all fundamental requirements in this application. The APS-1 detector converts the 2-D x-ray patterns to visible light images by a thin layer of x-ray sensitive phosphor. The phosphor coating is directly deposited on the large ends of nine fiber optic tapers arranged in a 3x3 array. Nine, thermoelectrically cooled 1024x 1024 pixel CCDs image the patterns, demagnified by the tapers. After geometrical and uniformity corrections, the nine areas give a continuous image of the detector face with virtually no gaps between the individual tapers. The 18 parallel analog signal-processing channels and analog-to-digital converters ensure short readout time and low readout noise. We discuss the design and measured performance of the detector.
Istvan Naday, Istvan Naday, Stephan W. Ross, Stephan W. Ross, Edwin M. Westbrook, Edwin M. Westbrook, George Zentai, George Zentai, } "Charge-coupled device/fiber optic taper array x-ray detector for protein crystallography," Optical Engineering 37(4), (1 April 1998). https://doi.org/10.1117/1.601789 . Submission:
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