2 September 2016 Highly integrated lab-on-a-chip for fluorescence detection
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We report the fabrication and validation of a microfluidic chip for fluorescence detection, which incorporates in the same glass substrate the microfluidic network, the excitation, the filtering, and the collection elements. The device is fabricated in a hybrid approach combining different technologies, such as femtosecond laser micromachining and RF sputtering, to increase their individual capabilities. The validation of the chip demonstrates a good wavelength selective light filtering and a limit of detection of a 600-nM concentration of Oxazine 720 perchlorate dye.
© 2016 Society of Photo-Optical Instrumentation Engineers (SPIE)
Surya S. K. Guduru, Surya S. K. Guduru, Francesco Scotognella, Francesco Scotognella, Alessandro Chiasera, Alessandro Chiasera, Valligatla Sreeramulu, Valligatla Sreeramulu, Luigino Criante, Luigino Criante, Krishna Chaitanya Vishnubhatla, Krishna Chaitanya Vishnubhatla, Maurizio Ferrari, Maurizio Ferrari, Roberta Ramponi, Roberta Ramponi, Guglielmo Lanzani, Guglielmo Lanzani, Rebeca Martínez Vázquez, Rebeca Martínez Vázquez, } "Highly integrated lab-on-a-chip for fluorescence detection," Optical Engineering 55(9), 097102 (2 September 2016). https://doi.org/10.1117/1.OE.55.9.097102 . Submission:

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