15 December 2017 Data preprocessing methods for robust Fourier ptychographic microscopy
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Fourier ptychographic microscopy (FPM) is a recently developed computational imaging technique that achieves gigapixel images with both high resolution and large field-of-view. In the current FPM experimental setup, the dark-field images with high-angle illuminations are easily overwhelmed by stray lights and background noises due to the low signal-to-noise ratio, thus significantly degrading the achievable resolution of the FPM approach. We provide an overall and systematic data preprocessing scheme to enhance the FPM’s performance, which involves sampling analysis, underexposed/overexposed treatments, background noises suppression, and stray lights elimination. It is demonstrated experimentally with both US Air Force (USAF) 1951 resolution target and biological samples that the benefit of the noise removal by these methods far outweighs the defect of the accompanying signal loss, as part of the lost signals can be compensated by the improved consistencies among the captured raw images. In addition, the reported nonparametric scheme could be further cooperated with the existing state-of-the-art algorithms with a great flexibility, facilitating a stronger noise-robust capability of the FPM approach in various applications.
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE)
Yan Zhang, Yan Zhang, An Pan, An Pan, Ming Lei, Ming Lei, Baoli Yao, Baoli Yao, } "Data preprocessing methods for robust Fourier ptychographic microscopy," Optical Engineering 56(12), 123107 (15 December 2017). https://doi.org/10.1117/1.OE.56.12.123107 . Submission: Received: 10 September 2017; Accepted: 28 November 2017
Received: 10 September 2017; Accepted: 28 November 2017; Published: 15 December 2017

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