The lack of data on water consumption by agriculture in the context of climate change led the authors to estimate the water balance of the Bekaa Valley. Plots were mapped according to the normalized difference vegetation index profiles of spring and summer crop with the Sentinels-2 images. Surface energy balance model python (PYSEBAL) estimated the seasonal evapotranspiration (ET_season) and net irrigation requirements (NIR_season). Spring and summer crop maps were accurate: 90% and 93%. The results of PYSEBAL were validated by the comparison between averaged daily ET of PYSEBAL and FAO-56 method (root mean square error from 0.38 to 1.93 and the mean average error from 0.33 to 1.64  mm  /  day). The water balance was negative: 0.16  km³ of groundwater was extracted against 0.10  km³ of rainfall available for aquifer recharge in 2017. This is explained by ET/ha/season (alfalfa: 1094  mm  /  ha  /  season, orchards 881, corn 719, tobacco 606, cucumber 558, late potatoes 487, summer vegetables 483, early potatoes 467, vineyard 390, spring vegetables 237, and wheat 313). ET_season varies according to temperature (strong correlation between daily ET and temperature, Pearson: 0.74), relative humidity (Pearson: −0.65), surface radiation (Pearson: 0.75), and percentage of sand in the soil and its depth (strong negative Pearson: −0.62 and −0.57).