Editor-in-Chief: Brian W. Pogue, University of Wisconsin–Madison, USA
Journal of Biomedical Optics (JBO) is a Gold Open Access journal that publishes peer-reviewed papers on the use of novel optical systems and techniques for improved health care and biomedical research.
On the cover: "Compact simultaneous label-free autofluorescence multi-harmonic microscopy for user-friendly photodamage-monitored imaging" by Geng Wang, Stephen A. Boppart, and Haohua Tu, in Volume 29 Issue 3.
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Regular papers: Submissions of regular papers are always welcome.
Special section papers: Open calls for papers are listed below. A cover letter indicating that the submission is intended for a particular special section should be included with the paper.
To submit a paper, please prepare the manuscript according to the journal guidelines and use the online submission system
. All papers will be peer‐reviewed in accordance with the journal's established policies and procedures. JBO is a Gold Open Access journal. Authors of accepted papers will be required to pay an article processing charge of $1675. Discounts may apply. Click here for more details.
In 1974, a Japanese bioengineer named Takuo Aoyagi, working for the Nihon Kohden Corp, developed a working prototype of an optical measurement system that sensed blood pulsation by detection of the temporal variation of light transmission through tissue. These changes showed that macroscopic measurements of diffuse light could directly sample variation in light absorption caused by dilation and constriction of arterial vessels at the heart rate frequency. Arguably, this electrical engineering advance would become perhaps the most impactful development in deep tissue biomedical optics. The discovery found wider recognition through the work of John Severinghaus, in the late-1980s, when functional pulse oximeters became commercially realized. All of this progress can be traced to a core discovery that diffuse light transmission through tissue carried temporal signatures with useful information from the microscopic blood vessel network.
The idea that spectroscopic measurement of these temporal signatures could be translated to quantitatively measure arterial blood oxygen saturation was revolutionary. Today pulse oximeters are ubiquitous in medicine, and the principles discovered in early pulse oximetry have ballooned to inspire many subsequent discoveries. The applications of imaging and sensing with diffuse light are extensive, as are the applications of related temporal and spectroscopic instrumentation and algorithms. In 2024, we celebrate the 50th anniversary of this discovery by a dedicated electrical engineer. The discovery eventually changed mainstream medical care, saving countless lives and transforming our ideas about what is possible with optical measurement through tissue.
For this special section of JBO, we are broadly seeking manuscripts on topics related to pulse oximetry, including Review papers, Perspective papers and original scientific manuscripts. Topics include:
All submissions will be peer reviewed. Peer review will commence immediately upon manuscript submission, with a goal of making a first decision within six weeks of manuscript submission. Special sections are opened online once a minimum of four papers have been accepted. Each paper is published as soon as the copyedited and typeset proofs are approved by the author. Submissions should follow the JBO author guidelines. Manuscripts should be submitted online at https://jbo.msubmit.net. A cover letter indicating that the submission is intended for this special section should be included.
Molecular Guided Surgery is an emerging field that brings together technological advances in instrumentation, computational methods and novel contrast agents. In the last decade or more, there have been dramatic advances across the field including regulatory clearances in specific devices and novel probes, as well as new indications for use in select surgeries. The Molecular Guided Surgery conference at SPIE BiOS is reaching its 10th anniversary in 2024, and interest has been strong throughout both academic and industry advances. This special issue of JBO is in honor of reaching this milestone of the conference, and to highlight novel imaging systems, agents, and methods that have advanced in this timeframe.
This special issue welcomes research and review papers on new aspects of Molecular Guided Surgery, including imaging systems, contrast agents, and fundamentally new tests of these. Topics for this special issue include endogenous signals and reporters, unique system designs, unique signal processing of these, correlations with histopathological imaging, intraoperative imaging, optical biopsy, functional image guided surgery, molecular and cellular imaging in vivo or in situ. The issue can also cover the associated topics of regulatory challenges and successes, tools for quantitative analyses, tissue phantoms for validation, tools and methods for standardization, modeling studies, model systems for testing in non-animal tissues. Original research papers, letters, perspective papers, or review papers are welcome.
All submissions will be peer reviewed. Peer review will commence immediately upon manuscript submission, with a goal of making a first decision within six weeks of manuscript submission. Each paper is published online as soon as the copyedited and typeset proofs are approved by the author.
Submissions should follow the JBO author guidelines. Manuscripts should be submitted online at https://jbo.msubmit.net. A cover letter indicating that the submission is intended for this special issue should be included.
Hyperspectral imaging (HSI) technologies, which initially were developed in the field of remote sensing, have been introduced to medical applications to augment conventional spectroscopic imaging technologies at the early stage. More recently, the technologies have increasingly been applied for a broad range of biomedical applications, including histologic evaluation of tumors in biopsy or post-lumpectomy tissues, enabling intraoperative evaluation of tissues, tumor margin assessment for image-guided surgery, etc. The key analysis goal of the hyperspectral data cubes and data sets is to determine whether a targeted spectral signature involving disease or anomaly is present or not in the data and spatially and spectrally resolve the target features. To this end, a variety of analysis algorithms have been demonstrated. With the advancement of AI technologies, especially deep-learning methods, the spectral-spatial analysis of the rich HSI data provides promising results that are not possible with conventional machine-learning methods.
This special issue will feature research and review papers on new hyperspectral imaging and detection devices and associated technologies, for application in the areas of translational research and clinical studies. Topics for this issue include hyperspectral technologies involving digital histopathological imaging, intraoperative imaging, optical biopsy, image-guide surgery, cellular imaging, etc. The issue also will cover the following relevant topics (but not limited to): quantitative analyses and modeling involving biological cells, tissues, and bio-mimicking phantoms towards measurement standards; data-supported perspectives and potential challenges in translating the hyperspectral techniques into the clinic; and discussions on the future research directions of biomedical applications of hyperspectral imaging, detection, and data-processing technologies.
All submissions will be peer reviewed. Peer review will commence immediately upon manuscript submission, with a goal of making a first decision within six weeks of manuscript submission. Each paper is published online as soon as the copyedited and typeset proofs are approved by the author.
Submissions should follow the JBO author guidelines. Manuscripts should be submitted online at https://jbo.msubmit.net. A cover letter indicating that the submission is intended for this special section should be included.
July 2024 marks the Third Britton Chance International Symposium on Metabolic Imaging and Spectroscopy at University of Pennsylvania honoring the memory of Professor Britton Chance. Prof. Chance was a prolific and legendary scientist who made pioneering contributions in the fields of radar, biochemistry, and biophysics, and who was a founding father of in vivo NMR and biomedical photonics. His research activities spanned physics, chemistry, engineering, biology, and medicine with aims to generate new understanding about tissue function and disease, and dreams to impact health science and clinical translation.
This JBO special issue welcomes submissions on topics in this spirit, e.g., focused on biomedical photonics and optical imaging/spectroscopy of tissue metabolism and related concepts. A range of topics can be explored, spanning from technical development, translation and clinical application of metabolic/functional imaging, and spectroscopy methods for disease detection, diagnosis, treatment, and prevention.
All submissions will be peer reviewed. Peer review will commence immediately upon manuscript submission, with a goal of making a first decision within six weeks of manuscript submission. Each paper is published online as soon as the copyedited and typeset proofs are approved by the author.
Submissions should follow the JBO author guidelines. Manuscripts should be submitted online at https://jbo.msubmit.net. A cover letter indicating that the submission is intended for this special issue should be included.
Special Issue Honoring Gabriel Popescu, Pioneer in Biomedical Optics (in progress, 2024)
Guest Editors: Randy A. Bartels, Stephen A. Boppart, and Kevin W. Eliceiri
Special Issue Honoring Lihong V. Wang, Pioneer in Biomedical Optics (in progress, 2024)
Guest Editors: Xueding Wang, Mark Anastasio, Hao Zhang, Sava Sakadzic, Song Hu, and Liang Gao
Polarimetry in Biomedical Optics (in progress: Part 1, October 2023; Part 2, May 2024)
Guest Editors: Alex Vitkin, Nirmalya Gosh, and Jessica C. Ramella-Roman
Selected Topics in Biophotonics: Translating Novel Photonics Technology into Clinical Applications (December 2023)
Guest Editors: Stefan Andersson-Engels and Peter E. Andersen
Short Wave Infrared Techniques and Applications in Biomedical Optics (September 2023)
Guest Editors: Daniel Fried, Mark Pierce, and Darren Roblyer
Seeing Inside Tissue with Optical Molecular Probes (August 2023)
Guest Editors: Nada Boustany, Mark Niedre, and Manojit Pramanik
30 Years of Open Source Monte Carlo Codes in Biomedical Optics (August 2022)
Guest Editors: Qianqian Fang, Fabrizio Martelli, and Lothar Lilge
Tissue Phantoms to Advance Biomedical Optical Systems (July 2022)
Guest Editors: Dimitris Gorpas, T. Joshua Pfefer, and Heidrun Wabnitz
Wearable, Implantable, Mobile, and Remote Biomedical Optics & Photonics (August 2020 - June 2021)
Guest Editors: Jessica Ramella-Roman, Amir H. Gandjbakhche, Stephen C. Kanick, Babak Shadgan, and Bruce J. Tromberg
Artificial Intelligence & Machine Learning in Biomedical Optics (September 2020 - May 2021)
Guest Editors: Behrouz Shabestri, Mark A. Anastasio, Baowei Fei, and Frédéric Leblond
Advances in Terahertz Biomedical Science and Applications (December 2020 - April 2021)
Guest Editors: Kirill I. Zaytsev, Vladimir N. Kurlov, Maksim Skorobogatiy, Igor V. Reshetov, and Valery V. Tuchin
Biomedical Imaging and Sensing III (two-part series: December 2020 and March 2021)
Guest Editors: Toyohiko Yatagai, Osamu Matoba, Yoshihisa Aizu, Yasuhiro Awatsuji, Osamu Matoba, and Yuan Luo
Selected Topics in Biophotonics: Fluorescence Lifetime Imaging and Optical Micromechanics (July 2020)
Guest Editors: Stefan Andersson-Engels and Peter E. Andersen
Photodynamic Therapy (June 2020)
Guest Editors: Kimberley S. Samkoe, Jonathan P. Celli, Timothy C. Zhu
Biomedical Imaging and Sensing II (March 2020)
Guest Editors: Toyohiko Yatagai, Yasuhiro Awatsuji, Osamu Matoba, Yuan Luo, and Yoshihisa Aizu
Celebrating Thirty Years of Multiphoton Microscopy in the Biomedical Sciences (January 2020)
Guest Editors: Ammasi Periasamy, Karsten König, and Peter T.C. So
Celebrating the Exponential Growth of Biomedical Optoacoustic/Photoacoustic Imaging (December 2019)
Guest Editors: Mark Anastasio, Paul Beard, Alexander A. Oraevsky, and Lihong V. Wang
Spatial Frequency Domain Imaging (July 2019)
Guest Editors: David Cuccia, Anthony Durkin, Sylvain Gioux, Amaan Mazhar, and Bruce Tromberg
Metabolic Imaging and Spectroscopy: Britton Chance 105th Birthday Commemorative (May 2019)
Guest Editors: Lin Z. Li, Arjun G. Yodh, and David Busch
Biomedical Imaging and Sensing (March 2019)
Guest Editors: Toyohiko Yatagai, Yasuhiro Awatsuji, Osamu Matoba, Yuan Luo, and Yoshihisa Aizu
Translational Biophotonics (February 2019)
Guest Editors: Bruce J. Tromberg, Gabriela Apiou, Markus Kleeman, and Regina Choe
Laser-Tissue Interaction and Optical Properties of Biological Tissues: Honoring Prof. Steven Jacques, a Pioneer in Biomedical Optics (December 2018)
Guest Editors: Jessica Ramella-Roman, Andreas Hielscher, and Lihong V. Wang
Topical Problems of Biophotonics: from Optical Bioimaging to Clinical Biophotonics (September 2018)
Guest Editors: Mikhail Kirillin, Kirill Larin, Ilya Turchin, and Valery Tuchin
Selected Topics in Biophotonics: Optogenetics and Label-Free Optical Spectroscopy (July 2018)
Guest Editors: Stefan Andersson-Engels and Peter E. Andersen
White Papers in Biophotonics (February 2018)
Guest Editor: David Sampson
25 years of OCT (December 2017)
Guest Editors: David Sampson, Peter Andersen, Ton van Leeuwen, and Ricky Wang
Translational Biophotonics (December 2017)
Guest Editors: Guest Editors: Bruce Tromberg, Gabriela Apiou, Darren Roblyer, and Aaron Aguirre
Advanced Laser Technologies for Biophotonics (September 2017)
Guest Editors: Martin J. Leahy, Tia E. Keyes, Valery V. Tuchin, and Alexander V. Priezzhev
Photoacoustic Imaging and Sensing (April 2017)
Guest Editors: Mark A. Anastasio, Paul C. Beard, and Qing Zhu
Translational Biophotonics (2016)
Guest Editors: Bruce Tromberg, Gabriela Apiou, Kristen Kelly, and Conor L. Evans
Adaptive Optics and Wavefront Control for Biological Systems (December 2016)
Guest Editors: Thomas G. Bifano, Joel A. Kubby, and Sylvain Gigan
Optical Diagnostic and Biophotonic Methods from Bench to Bedside (October 2016)
Guest Editors: Amir Gandjbakhche, Bruce Tromberg, Israel Gannot, Jana M. Kainerstorfer, and Fatima Chowdhry
Clinical Near-Infrared Spectroscopy and Imaging (September 2016)
Guest Editors: Marco Ferrari, Joseph P. Culver, Yoko Hoshi, and Heidrun Wabnitz
Tissue and Blood Optical Clearing for Biomedical Applications (August 2016)
Guest Editors: Dan Zhu, Bernard Choi, Elina Genina, Valery V. Tuchin
Polarized Light for Biomedical Applications (July 2016)
Guest Editors: Igor Meglinski, Tatiana Novikova, Jessica C. Ramella-Roman, and Valery V. Tuchin
Selected Topics in Biophotonics: Photoacoustic Tomography and Fiber-Based Lasers and Supercontinuum Sources (June 2016)
Guest Editors: Stefan Andersson-Engels and Peter E. Andersen
Optical Medical Imaging Standards (December 2015)
Guest Editors: David W. Allen, Maritoni Litorja, and Jeeseong Hwang
Quantitative Phase Imaging in Biomedicine (November 2015)
Guest Editors: Gabriel Popescu and YongKeun Park
Protein Photonics for Imaging, Sensing, and Manipulation: Honoring Prof. Osamu Shimomura, a Pioneer of Photonics for Biomedical Research (October 2015)
Guest Editors: Katsumasa Fujita, Takeharu Nagai, Nathan Shaner, and Alexnader Egner
Light for Life: International Year of Light 2015 (June 2015)
Guest Editors: Rainer Leitgeb, Katarina Svanberg, Nimmi Ramanujam, Jürgen Popp, and Peter Andersen
Laser Applications in Life Sciences (May 2015)
Guest Editors: Alexander V. Priezzhev, Herbert Schneckenburger, and Valery V. Tuchin
Vibrational Spectroscopy and Imaging (November 2014)
Guest Editors: Anita Mahadevan-Jansen, Michael D. Morris, and Wolfgang Petrich
Biomimetic and Bioinspired Materials for Applications in Biophotonics (October 2014)
Guest Editors: Bahman Anvari, Pablo del Pino, Vikas Kundra, and Wolfgang Parak
Selected Topics in Biophotonics: Optical Coherence Tomography and Biomolecular Imaging with Coherent Raman Scattering Microscopy (July 2014)
Guest Editors: Stefan Andersson-Engels and Peter E. Andersen
Nanobio-Based Optical Sensing and Imaging (May 2014)
Guest Editors: Min-Gon Kim, Woo Keun Song, Kun Ho Lee, and Bahman Anvari
Optical Coherence Tomography and Interferometry: Advanced Engineering and Biomedical Applications (February 2014)
Guest Editors: Valery V. Tuchin, Kirill V. Larin, and Alex Vitkin
Advanced Biomedical Imaging and Sensing (January 2014)
Guest Editors: Chi-Kuang Sun, Arthur Chiou, Fu-Jen Kao, Chien Chou, and Chen-Yuan Dong
Special Section on Optical Elastography and Measurement of Tissue Biomechanics (December 2013)
Guest Editors: Ruikang K. Wang, David D. Sampson, Stephen A. Boppart, and Brendan F. Kennedy
Optical Imaging, Sensing, and Light Interactions in Cells and Tissues (November 2013)
Guest Editors: Natan T. Shaked, Shy Shoham, Bruce J. Tromberg, and Israel Gannot
Special Section on Fluorescence Molecular Imaging Honoring Prof. Roger Tsien, a Pioneer in Biomedical Optics (October 2013)
Guest Editors: Vasilis Ntziachristos, Samuel Achilefu, Yingxiao Peter Wang, and Michael Lin
Optical Methods of Imaging in the Skin (June 2013)
Guest Editor: Jürgen Lademann
Multiphoton Microscopy: Technical Innovations, Biological Applications, and Clinical Diagnostics (March 2013)
Guest Editors: Paul J. Campagnola, Chen-Yuan Dong, Karsten Koenig, Jerome Mertz, Peter T. C. So, Chris Xu
Laser Technologies for Biomedical Applications (October 2012)
Guest Editors: Ekaterina Borisova, Herbert Schneckenburger, Alexander Priezzhev
Optical Diagnostic and Biophotonic Methods from Bench to Bedside (August 2012)
Guest Editors: Amir Gandjbakhche, Jana M. Kainerstorfer, and Bruce Tromberg
Selected Topics in Biophotonics: Optical Coherence Tomography and Medical Imaging Using Diffuse Optics (July 2012)
Guest Editors: Stefan Andersson-Engels and Peter E. Andersen
Photoacoustic Imaging and Sensing (June 2012)
Guest Editors: Mark A. Anastasio and Paul C. Beard
Endomicroscopy Technologies and Biomedical Applications (February 2012)
Guest editors: Xingde Li and Warren S. Grundfest
FRET at 65 (January 2012)
Guest editors: Ammasi Periasamy, Steven S. Vogel, and Robert M. Clegg
Hard-Tissue Optics and Related Methods (July 2011)
Guest editors: Daniel Fried, Andreas Mandelis, and Michael Morris
Photonics and Nanotechnology in Biophysics and Biomedical Research (May 2011)
Guest editors: Bahman Anvari, Raoul Kopelman, and Luke P. Lee
Coherent Raman Imaging Techniques and Biomedical Applications (February 2011)
Guest editors: Eric O. Potma, Ji-Xin Cheng, and X. Sunney Xie
Pioneers in Biomedical Optics: Michael Feld (January 2011)
Guest Editors: Ramachandra Dasari, Rebecca Richards-Kortum, and Andrew Berger
Optical Diagnostic and Biophotonic Methods from Bench to Bedside (November/December 2010)
Guest Editors: Amir Gandjbakhche, Bruce Tromberg, and Jana Maria Kainerstorfer
Pioneers in Biomedical Optics: Prof. Tayyaba Hasan (September/October 2010)
Guest Editors: Brian W. Pogue, Georges A. Wagnieres, and Lothar D. Lilge
Selected Topics in Biophotonics: Photodynamic Therapy and Optical Micromanipulation for Biophotonics (July/August 2010)
Guest Editors: Stefan Andersson-Engels and Peter E. Andersen
Photons Plus Ultrasound: Imaging and Sensing (March/April 2010)
Guest Editors: Lihong V. Wang and Alexander A. Oraevsky
Optical Methods in Vascular Biology and Medicine (January/February 2010)
Guest Editors: Bernard Choi, Brett Bouma, Dai Fukumura, and Rakesh K. Jain
Nanophotonics for Diagnostics, Protection, and Treatment of Cancer and Inflammatory Diseases (March/April 2009)
Guest Editors: Valery V. Tuchin, Rebekah Drezek, Shuming Nie, and Vladimir P. Zharov
Selected Topics in Biophotonics: Diffuse Optics and Optical Molecular Imaging (July/August 2008)
Guest Editors: Stefan Andersson-Engels and Peter E. Andersen
Visible Fluorescent Proteins (May/June 2008)
Guest Editors: Alberto "Alby" Diaspro and Ammasi Periasamy
Optical Clearing of Tissues and Cells (March/April 2008)
Guest Editors: Valery V. Tuchin, Ruikang K. Wang, and Alvin T. Yeh
Small-Animal Optical Imaging (January/February 2008)
Guest Editors: Vasilis Ntziachristos, Joseph P. Culver, and Bradley W. Rice
Pioneers in Biomedical Optics: Honoring F.F. Jobsis (November/December 2007)
Guest Editors: David T. Delpy, Marco Ferrari, Claude A. Piantadosi, and Mamoru Tamura
Optical Diagnostic Imaging from Bench to Bedside (September/October 2007)
Guest Editors: Amir Gandjbakhche and Abby Vogel
Optical Coherence Tomography in Ophtalmology (July/August 2007)
Guest Editors: Wolfgang Drexler and James G. Fujimoto
Photonics in the Auditory System (March/April 2007)
Guest Editors: Bahman Anvari, William E. Brownell, Dennis M. Freeman, and Mats Ulfendahl
Pioneers in Biomedical Optics: Honoring Professor Ashley J. Welch (July/August 2006)
Guest Editors: E. Duco Jansen and Sohi Rastegar
Cardiovascular Photonics (March/April 2006)
Guest Editors: Laura Marcu, Guillermo J. Tearney, and Kenton W. Gregory
Optical Diagnostic Imaging from Bench to Bedside (September/October 2005)
Guest Editors: Amir Gandjbakhche and Israel Gannot
Chemical and Genetic Sensors in Biomedical Research (July/August 2005)
Guest Editors: Samuel Achilefu, Christopher H. Contag, Alexander P. Savitsky, and Ralph Weissleder
Infrared and Raman Spectroscopy (May/June 2005)
Guest Editors: Michael D. Morris, Andrew Berger, and Anita Mahadevan-Jansen
Optics in Neuroscience (January/February 2005)
Guest Editors: David A. Boas, Ph.D. and Ron D. Frostig, Ph.D.
Optics in Breast Cancer (November 2004)
Guest Editors: Sergio Fantini, Ph.D., K. Thomas Moesta, M.D., and Brian W. Pogue, Ph.D.
Pioneers in Biomedical Optics: Prof. Watt Webb (September 2004)
Guest Editors: David W. Piston and Elliott Elson
Biomedical Optics and Women's Health (May 2004)
Guest Editors: Rebecca Richards-Kortum and Michele Follen
Optics of the Human Skin (March 2004)
Guest Editor: J. Stuart Nelson
Ophthalmic Diagnostics (January 2004)
Guest Editors: Rafat R. Ansari and J. Sebag
Multiphoton Microscopy (July 2003)
Guest Editors: Ammasi Periasamy Ph.D. and Alberto Diaspro Ph.D.
Tools for Biomolecular and Cellular Analysis (October 2002)
Guest Editors: Richard B. Thompson and Fran Ligler
Tissue Polarimetry (July 2002)
Guest Editors: Lihong V. Wang, Gerard L. Coté, and Steven L. Jacques
Optical Imaging and Spectroscopy: From Benchtop to Bedside (January 2002)
Guest Editors: Amir H. Gandjbakhche, Michael Patterson, and Michele Follen
Frontiers in Microscopy (July 2001)
Guest Editors: M. J. Booth and T. Wilson
Advances in Contrast Agents, Reporters, and Detection (April 2001)
Guest Editors: Darryl J. Bornhop, Christopher H. Contag, Kai Licha, and Catherine J. Murphy
Continuation of Special Issue Honoring Professor Britton Chance (July 2000)
Special Issue Honoring Professor Britton Chance (April 2000)
Guest Editors: Arjun G. Yodh and Bruce J. Tromberg
Medical Near-Infrared Spectroscopy (October 1999)
Guest Editors: Kazuo Okada and Takafumi Hamaoka
Photodynamic Therapy (July 1999)
Guest Editors: Piotr Ziókowski, Krzysztof Symonowicz, Beata J. Osiecka, Jerzy Rabczyski, and Jerzy Gerber
Biomedical Applications of Vibrational Spectroscopic Imaging (January 1999)
Guest Editor: Michael D. Morris
Optical Diagnostics of Biological Fluids (January 1999)
Guest Editors: Alexander V. Priezzhev and Toshimitsu Asakura
Coherence Domain Optical Methods in Biomedical Science and Clinics (January 1999)
Guest Editors: Valery V. Tuchin, Halina Podbielska, and Christoph K. Hitzenberger
Interferometry in Biomedicine: part 2 (July 1998)
Interferometry in Biomedicine: part 1 (January 1998)
Guest Editors: Halina Podbielska, Christoph K. Hitzenberger, and Valery V. Tuchin
Near Infrared Spectroscopy and Imaging of Tissues (October 1996)
Guest Editors: Marco Ferrari, David T. Delpy, and David A. Benaron
Light Scatter and Fluorescence of the Eye Lens (July 1996)
Guest Editor: Barbara K. Pierscionek
