Summary of studies on the blue-green autofluorescence and light transmission of the ocular lens

Jaap A. Van Best; Esmeralda V.M.J. Kuppens

doi:10.1117/12.241531

1 July 1996 Summary of studies on the blue-green autofluorescence and light transmission of the ocular lens

Jaap A. Van Best, Esmeralda V.M.J. Kuppens

Author Affiliations +

Journal of Biomedical Optics, Vol. 1, Issue 3, (July 1996). https://doi.org/10.1117/12.241531

Abstract

This paper reviews previous work done to demonstrate the clinical relevance of the measurement of bluegreen autofluorescence and light transmission of the ocular lens (l=450 to 550 nm). These can be determined quantitatively with fluorophotometry in a few seconds. Autofluorescence and transmission values are determined in healthy volunteers, in patients with insulin-dependent diabetes mellitus, and in patients with untreated glaucoma or untreated ocular hypertension. The lens autofluorescence of healthy volunteers increased linearly and transmission decreased exponentially with age. Each year of diabetes induced an increase of autofluorescence equal to one extra year of age. Untreated glaucoma or ocular hypertension had no significant effect on lens autofluorescence and transmission. Increased autofluorescence and decreased transmission values in comparison with values of a healthy population are proved to be indicative for an increased risk of developing cataract and the clinical usefulness of these measures is demonstrated. Diabetes is a risk factor for developing cataract while untreated glaucoma or ocular hypertension is not.

Citation Download Citation

Jaap A. Van Best and Esmeralda V.M.J. Kuppens "Summary of studies on the blue-green autofluorescence and light transmission of the ocular lens," Journal of Biomedical Optics 1(3), (1 July 1996). https://doi.org/10.1117/12.241531

Published: 1 July 1996

Access the abstract

JOURNAL ARTICLE
8 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

CITATIONS

Cited by 14 scholarly publications.

Explore citations on Lens.org

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Luminescence

Eye

Solids

Proteins

In vivo imaging

Lamps

Ultraviolet radiation

Show All Keywords

RELATED CONTENT

Measurement and quantification of fluorescent changes in ocular tissue using...
Proceedings of SPIE (May 08 2014)

In Vivo Measurements On Human Lens Using Quasielastic Light Scattering
Proceedings of SPIE (August 05 1986)

Physical properties of leaf level fluorescence
Proceedings of SPIE (July 02 1997)

Fluorescence spectra and magnetic resonance imaging of the ocular lens
Proceedings of SPIE (August 14 1992)

Influence of the light induced molecular transformations on the helix...
Proceedings of SPIE (July 20 2004)

Diagnostic Evaluation of Human Lenses
Proceedings of SPIE (August 05 1986)

Biomedical application of metalloporphyrins room-temperature phosphorescence
Proceedings of SPIE (May 18 1993)

Subscribe to Digital Library

Receive Erratum Email Alert

Show All Keywords

Keywords/Phrases

Search In:

Publication Years