journal of biomedical optics
VOL. 13 · NO. 5 | September 2008
CONTENTS
IN THIS ISSUE

Errata (1)
JBO Letters
J. Biomed. Opt. 13(5), 050501 (1 September 2008) doi:10.1117/1.2981797
TOPICS: Tissue optics, Tissues, Tumor growth modeling, Optical properties, Diffuse reflectance spectroscopy, Absorption, Data modeling, Scattering, Reflectivity, Calibration
J. Biomed. Opt. 13(5), 050502 (1 September 2008) doi:10.1117/1.2981817
TOPICS: Second-harmonic generation, Multiphoton microscopy, In vivo imaging, Imaging systems, Harmonic generation, Microscopy, Organisms, Biology, Digestive system, Auto-fluorescence imaging
J. Biomed. Opt. 13(5), 050503 (1 September 2008) doi:10.1117/1.2981806
TOPICS: Image classification, Tomography, Absorption, Diagnostics, Scattering, Neurons, Laser scattering, Quantization, Optical tomography, Neural networks
J. Biomed. Opt. 13(5), 050504 (1 September 2008) doi:10.1117/1.2981813
TOPICS: Photodynamic therapy, Oxygen, Luminescence, In vivo imaging, Skin, Picosecond phenomena, Dermatology, Signal detection, Phototherapy, Oncology
Han-Wen Guo, Chien-Tsun Chen, Yau-Huei Wei, Oscar Lee, Vladimir Ghukasyan, Fu-Jen Kao, Hsing-Wen Wang
J. Biomed. Opt. 13(5), 050505 (1 September 2008) doi:10.1117/1.2990752
TOPICS: Luminescence, Stem cells, Picosecond phenomena, Mode conditioning cables, Acquisition tracking and pointing, In vivo imaging, Fluorescence lifetime imaging, Solids, Biomedical optics, Molecular biology
J. Biomed. Opt. 13(5), 050507 (1 September 2008) doi:10.1117/1.2992595
TOPICS: Luminescence, Microscopy, Confocal microscopy, Spatial resolution, Molecules, Demodulation, Molecular lasers, Modulation, Nonlinear optics, Signal detection
J. Biomed. Opt. 13(5), 050508 (1 September 2008) doi:10.1117/1.2997375
TOPICS: Laser microsurgery, Microscopy, Laser systems engineering, Phase imaging, Camera shutters, Laser processing, Mirrors, Objectives, Image processing, Blood
J. Biomed. Opt. 13(5), 050509 (1 September 2008) doi:10.1117/1.2998473
TOPICS: Optical properties, Modulation, Semiconductor lasers, Liquids, Imaging spectroscopy, Network security, Photonic devices, Absorption, Scattering, Tissue optics
J. Biomed. Opt. 13(5), 050510 (1 September 2008) doi:10.1117/1.3005421
TOPICS: Ultrasonography, Photoacoustic spectroscopy, Imaging systems, Photoacoustic imaging, Blood vessels, Image visualization, In vivo imaging, Computing systems, Transducers, Visualization
Research Papers
J. Biomed. Opt. 13(5), 054001 (1 September 2008) doi:10.1117/1.2981828
TOPICS: Confocal microscopy, Tumors, Tissues, Mohs surgery, Surgery, Luminescence, Skin, Microscopy, Reflectivity, Microscopes
J. Biomed. Opt. 13(5), 054002 (1 September 2008) doi:10.1117/1.2978061
TOPICS: Raman spectroscopy, Proteins, Cell death, Oxygen, Glucose, Spectroscopy, Tumors, Biological research, Tissues, Statistical analysis
Alexandre Dupuis, Ning Guo, Yan Gao, Olga Skorobogata, Bertrand Gauvreau, Charles Dubois, Maksim Skorobogatiy
J. Biomed. Opt. 13(5), 054003 (1 September 2008) doi:10.1117/1.2978062
TOPICS: Optical fibers, Polymers, Polymer optical fibers, Refractive index, Cladding, Polymer thin films, In vivo imaging, Step index fibers, Fabrication, Multilayers
J. Biomed. Opt. 13(5), 054004 (1 September 2008) doi:10.1117/1.2978064
TOPICS: Blood, Raman spectroscopy, Signal detection, Raman scattering, Laser beam diagnostics, Molecules, Chemical analysis, Spectral resolution, Applied physics, In vivo imaging
J. Biomed. Opt. 13(5), 054005 (1 September 2008) doi:10.1117/1.2978066
TOPICS: Retina, Near infrared, Eye, Absorption, Cornea, Eye models, Laser damage threshold, Data modeling, Continuous wave operation
Junghwan Oh, Marc Feldman, H. Golombek, Jihoon Kim, Pramod Sanghi, Dat Do, J. Jacob Mancuso, Nathaniel Kemp, Mehmet Cilingiroglu, Thomas Milner
J. Biomed. Opt. 13(5), 054006 (1 September 2008) doi:10.1117/1.2985762
TOPICS: Magnetism, Nanoparticles, Tissues, Natural surfaces, Tissue optics, Optical coherence tomography, Iron, Oxides, Interference (communication), Control systems
Zhijia Yuan, Zhenguo Wang, Rubin Pan, Jingxuan Liu, Harris Cohen, Yingtian Pan
J. Biomed. Opt. 13(5), 054007 (1 September 2008) doi:10.1117/1.2978059
TOPICS: Optical coherence tomography, Bladder, Bladder cancer, Tumors, Backscatter, Cancer, Ultrasonography, Image segmentation, Tumor growth modeling, Image resolution
Takusige Katura, Hiroki Sato, Yutaka Fuchino, Takamasa Yoshida, Hirokazu Atsumori, Masashi Kiguchi, Atsushi Maki, Masanori Abe, Naoki Tanaka
J. Biomed. Opt. 13(5), 054008 (1 September 2008) doi:10.1117/1.2981829
TOPICS: Independent component analysis, Hemodynamics, Biomedical optics, Model-based design, Interference (communication), Cortical activation, Functional magnetic resonance imaging, Analytical research, Brain, Heart
J. Biomed. Opt. 13(5), 054009 (1 September 2008) doi:10.1117/1.2975962
TOPICS: Tissues, Diffuse reflectance spectroscopy, Breast, Luminescence, Raman spectroscopy, Tissue optics, Diagnostics, Algorithm development, Spectroscopy, Pathology
J. Biomed. Opt. 13(5), 054010 (1 September 2008) doi:10.1117/1.2975866
TOPICS: Luminescence, Tissues, Tissue optics, Collagen, Confocal microscopy, Spectroscopy, Second-harmonic generation, Optical fibers, Fluorescence spectroscopy, Mirrors
J. Biomed. Opt. 13(5), 054011 (1 September 2008) doi:10.1117/1.2975831
TOPICS: Cell death, Luminescence, Picosecond phenomena, Control systems, Fluorescence lifetime imaging, Photon counting, Data acquisition, Data modeling, Acquisition tracking and pointing, Ultrasonography
William Hucker, Crystal Ripplinger, Christine Fleming, Vadim Fedorov, Andrew Rollins, Igor Efimov
J. Biomed. Opt. 13(5), 054012 (1 September 2008) doi:10.1117/1.2975826
TOPICS: Optical coherence tomography, Tissue optics, Tissues, Natural surfaces, Biomedical optics, Associative arrays, Heart, 3D image processing, Photodiodes, Biomedical engineering
Wieslaw Srodka, Barbara Pierscionek
J. Biomed. Opt. 13(5), 054013 (1 September 2008) doi:10.1117/1.2975844
TOPICS: Cornea, Sclera, Eye, Eye models, Thin film coatings, Image quality, Biomedical optics, Finite element methods, Mercury, Tissues
J. Biomed. Opt. 13(5), 054014 (1 September 2008) doi:10.1117/1.2981831
TOPICS: In vitro testing, Animal model studies, Data modeling, Laser damage threshold, Eye models, In vivo imaging, Retina, Mathematical modeling, Beam shaping, Laser induced damage
Martin Hammer, Walthard Vilser, Thomas Riemer, Dietrich Schweitzer
J. Biomed. Opt. 13(5), 054015 (1 September 2008) doi:10.1117/1.2976032
TOPICS: Oxygen, Cameras, Oximetry, Image segmentation, Calibration, Optical filters, Oximeters, Spectroscopy, Absorbance, Diagnostics
J. Biomed. Opt. 13(5), 054016 (1 September 2008) doi:10.1117/1.2982529
TOPICS: Speckle, Speckle pattern, Optical fibers, Time metrology, Motion measurement, Fiber lasers, Laser speckle imaging, Diagnostics, Image transmission, In vivo imaging
Paolo Bianchini, Daniela Calzia, Silvia Ravera, Giovanni Candiano, Angela Bachi, Alessandro Morelli, Maurizio Bruschi, Isidoro Pepe, Alberto Diaspro, Isabella Panfoli
J. Biomed. Opt. 13(5), 054017 (1 September 2008) doi:10.1117/1.2982528
TOPICS: Retina, Luminescence, Rods, Retinal scanning, Eye, Image segmentation, Confocal microscopy, 3D image reconstruction, Electron transport, Acquisition tracking and pointing
Frederic von Wegner, Tobias Ober, Cornelia Weber, Sebastian Schürmann, Rene Winter, Oliver Friedrich, Rainer Fink, Martin Vogel
J. Biomed. Opt. 13(5), 054018 (1 September 2008) doi:10.1117/1.2982525
TOPICS: Image segmentation, Denoising, Optical flow, Luminescence, Proteins, Wavelets, In vitro testing, 3D image processing, Signal to noise ratio, Image processing algorithms and systems
Louis Gagnon, Claudine Gauthier, Richard Hoge, Frederic Lesage, Juliette Selb, David Boas
J. Biomed. Opt. 13(5), 054019 (1 September 2008) doi:10.1117/1.2982524
TOPICS: Brain, Absorption, Skin, Monte Carlo methods, In vivo imaging, Tissues, Data modeling, Biological research, Scattering, Oxygen
Jeremy Rogers, Sara Landau, Tomasz Tkaczyk, Michael Descour, Mohammed Rahman, Rebecca Richards-Kortum, Ari Karkkainen, Todd Christenson
J. Biomed. Opt. 13(5), 054020 (1 September 2008) doi:10.1117/1.2978060
TOPICS: Modulation transfer functions, Tissues, Relays, Imaging systems, Reflectivity, Luminescence, Microscopes, Quantum dots, Tissue optics, Gold
J. Biomed. Opt. 13(5), 054021 (1 September 2008) doi:10.1117/1.2978067
TOPICS: Luminescence, Metals, Molecules, Silica, Data modeling, Surface plasmons, Silver, Glasses, Fluorescence spectroscopy, Refractive index
James Kah, Weber Lau, Phuay Tan, Colin James Sheppard, Malini Olivo
J. Biomed. Opt. 13(5), 054022 (1 September 2008) doi:10.1117/1.2981827
TOPICS: Luminescence, Bladder cancer, Tissues, Image analysis, Cancer, Diagnostics, Bladder, Tissue optics, Endoscopy, Tumors
Satoko Kakino, Yuzo Takagi, Setsuo Takatani
J. Biomed. Opt. 13(5), 054023 (1 September 2008) doi:10.1117/1.2976112
TOPICS: Teeth, Blood, Scattering, Absorption, Optical testing, Light scattering, Monte Carlo methods, Geometrical optics, Light wave propagation, Photon transport
Shuangmu Zhuo, Jianxin Chen, Biying Yu, Xingshan Jiang, Teng Leo, Quangang Liu, Rong Chen, Shusen Xie
J. Biomed. Opt. 13(5), 054024 (1 September 2008) doi:10.1117/1.2982534
TOPICS: Second-harmonic generation, Collagen, Tissues, Microscopy, Optical microscopy, Tissue optics, Luminescence, Optical fibers, Cartilage, In vivo imaging
Monica Monici, Venere Basile, Giovanni Romano, Lucia Evangelisti, Laura Lucarini, Monica Attanasio, Enrico Bertini, Franco Fusi, Gian Gensini, Guglielmina Pepe
J. Biomed. Opt. 13(5), 054025 (1 September 2008) doi:10.1117/1.2982533
TOPICS: Atrial fibrillation, Connective tissue, Luminescence, Diagnostics, Multispectral imaging, Mode conditioning cables, Optical filters, Imaging spectroscopy, RGB color model, Microscopy
Kiang-Wei Kho, Zhu Mei Qing, Ze-Xiang Shen, Iman Ahmad, S. Lim, Subodh Mhaisalkar, Timothy White, Frank Watt, Kee Chee Soo, Malini Olivo
J. Biomed. Opt. 13(5), 054026 (1 September 2008) doi:10.1117/1.2976140
TOPICS: Microfluidics, Surface enhanced Raman spectroscopy, Nanostructures, Raman spectroscopy, Polymers, Molecules, Metals, Biological research, Gold, Statistical analysis
Dennis Hsu, Cynthia Darling, Margarita Lachica, Daniel Fried
J. Biomed. Opt. 13(5), 054027 (1 September 2008) doi:10.1117/1.2976113
TOPICS: Reflectivity, Minerals, Optical coherence tomography, Luminescence, Fluorine, Nondestructive evaluation, Gas lasers, Laser therapeutics, Teeth, Laser induced fluorescence
J. Biomed. Opt. 13(5), 054028 (1 September 2008) doi:10.1117/1.2976141
TOPICS: Imaging systems, Ultrasonography, Photoacoustic microscopy, 3D image processing, Photoacoustic imaging, 3D photoacoustic microscopy, In vivo imaging, Photoacoustic spectroscopy, Stereoscopy, Skin
Herculano Martinho, Claudia Maria da Silva, Maria Christina Mendonca Yassoyama, Patricia Andrade, Renata Bitar, Ana Maria Espirito Santo, Emilia Loschiavo Arisawa, Airton Martin
J. Biomed. Opt. 13(5), 054029 (1 September 2008) doi:10.1117/1.2976114
TOPICS: Cervix, Raman spectroscopy, Tissues, Biopsy, Lawrencium, Tissue optics, Principal component analysis, Data modeling, Cervical cancer, Biomedical optics
Erik Haggblad, Tobias Lindbergh, Daniel Karlsson, Henrik Casimir-Ahn, Göran Salerud, Tomas Strömberg
J. Biomed. Opt. 13(5), 054030 (1 September 2008) doi:10.1117/1.2976433
TOPICS: Tissue optics, Tissues, Calibration, Absorption, Heart, Scattering, Arteries, Blood, Data modeling, Diffuse reflectance spectroscopy
Solomon Diamond, David Boas, Theodore Huppert
J. Biomed. Opt. 13(5), 054031 (1 September 2008) doi:10.1117/1.2976432
J. Biomed. Opt. 13(5), 054032 (1 September 2008) doi:10.1117/1.2976430
TOPICS: Scattering, Tissues, Light scattering, Optical coherence tomography, Liquids, Solids, Polarization, Signal to noise ratio, Particles, Scatter measurement
Kwang Hyun Song, Erich Stein, Julie Margenthaler, Lihong Wang
J. Biomed. Opt. 13(5), 054033 (1 September 2008) doi:10.1117/1.2976427
TOPICS: Photoacoustic spectroscopy, In vivo imaging, Lymphatic system, Imaging systems, Ultrasonics, Tissue optics, Transducers, Breast, Skin, Tissues
Tuqiang Xie, Yang Xia, Shuguang Guo, Patrick Hoover, Zhongping Chen, George Peavy
J. Biomed. Opt. 13(5), 054034 (1 September 2008) doi:10.1117/1.2976422
TOPICS: Tissue optics, Cartilage, Collagen, Polarization, Optical coherence tomography, Tissues, Natural surfaces, Birefringence, Microscopy, Polarized microscopy
Emilie Roncali, Mickael Savinaud, Olivier Levrey, Kelly Rogers, Serge Maitrejean, Bertrand Tavitian
J. Biomed. Opt. 13(5), 054035 (1 September 2008) doi:10.1117/1.2976426
TOPICS: Video, Bioluminescence, Signal to noise ratio, Real time imaging, Imaging systems, CCD cameras, Signal detection, Infrared cameras, Cameras, Light sources and illumination
Dan Fu, Tong Ye, Thomas Matthews, James Grichnik, Lian Hong, John Simon, Warren Warren
J. Biomed. Opt. 13(5), 054036 (1 September 2008) doi:10.1117/1.2976424
TOPICS: Skin, Absorption, Melanoma, Tissues, Signal to noise ratio, Phase shift keying, Thermal effects, Modulation, Laser beam diagnostics, Photothermal effect
J. Biomed. Opt. 13(5), 054037 (1 September 2008) doi:10.1117/1.2976425
TOPICS: Chromophores, Scattering, Near infrared, Inverse problems, Tissue optics, Condition numbers, Image restoration, Absorption, Data modeling, Light scattering
Karl Schulmeister, Johannes Husinsky, Bernhard Seiser, Florian Edthofer, Beate Fekete, Letizia Farmer, David Lund
J. Biomed. Opt. 13(5), 054038 (1 September 2008) doi:10.1117/1.2982526
TOPICS: Laser damage threshold, Data modeling, Computer simulations, Retina, Thermal modeling, In vivo imaging, Pulsed laser operation, Injuries, Sensors, Laser induced damage
Fernand Cohen, Ezgi Taslidere, Dilip Hari, Sreekant Murthy
J. Biomed. Opt. 13(5), 054039 (1 September 2008) doi:10.1117/1.2982527
TOPICS: Tissues, Light scattering, Scattering, Optical spheres, Inflammation, Stochastic processes, Data modeling, Mie scattering, Feature extraction, Colon
Nina Reitan, Aphirak Juthajan, Tore Lindmo, Catharina de Lange Davies
J. Biomed. Opt. 13(5), 054040 (1 September 2008) doi:10.1117/1.2982530
TOPICS: Diffusion, Fluorescence correlation spectroscopy, Systems modeling, Molecules, Data modeling, Tissues, Macromolecules, Tumors, Luminescence, Particles
Mathias Strupler, Monica Hernest, Cecile Fligny, Jean-Louis Martin, Pierre-Louis Tharaux, Marie-Claire Schanne-Klein
J. Biomed. Opt. 13(5), 054041 (1 September 2008) doi:10.1117/1.2981830
TOPICS: Second-harmonic generation, Collagen, Kidney, Arteries, Microscopy, Optical fibers, Tissues, Multiphoton microscopy, Image segmentation, Biopsy
J. Biomed. Opt. 13(5), 054042 (1 September 2008) doi:10.1117/1.2982535
TOPICS: In vivo imaging, Luminescence, Near infrared, In vitro testing, Liver, Tissues, Bladder, Proteins, Kidney, Molecules
Madoka Nakao, Shigeto Yoshida, Shinji Tanaka, Yoshito Takemura, Shiro Oka, Masaharu Yoshihara, Kazuaki Chayama
J. Biomed. Opt. 13(5), 054043 (1 September 2008) doi:10.1117/1.2983674
TOPICS: Cancer, Endoscopy, Visualization, Biopsy, Confocal microscopy, Stomach, In vivo imaging, Biomedical optics, Laser tissue interaction, Esophagus
J. Biomed. Opt. 13(5), 054044 (1 September 2008) doi:10.1117/1.2982523
TOPICS: Absorption, Blood, Scattering, Error analysis, Data modeling, Reflectance spectroscopy, In vivo imaging, Spectroscopy, Statistical analysis, Chromophores
Christian Zakian, Iain Pretty, Roger Ellwood, David Hamlin
J. Biomed. Opt. 13(5), 054045 (1 September 2008) doi:10.1117/1.2982536
TOPICS: Inflammation, Zinc, Blood, Absorption, Imaging spectroscopy, Tissues, Reflectivity, Skin, In vivo imaging, Blood circulation
J. Biomed. Opt. 13(5), 054046 (1 September 2008) doi:10.1117/1.2983671
TOPICS: Ultrasonography, Transducers, Modulation, Ultrasound-modulated optical tomography, Tissues, Image resolution, Tissue optics, Scattering, Light scattering, Biomedical optics
Marco Pilz, Sibylle Honold, Alwin Kienle
J. Biomed. Opt. 13(5), 054047 (1 September 2008) doi:10.1117/1.2983675
TOPICS: Point spread functions, Cameras, Tissue optics, Optical properties, Imaging systems, Scattering, Convolution, Absorption, Reflectivity, CCD cameras
J. Biomed. Opt. 13(5), 054048 (1 September 2008) doi:10.1117/1.2983676
TOPICS: Optical fibers, Refractive index, Water, Biological research, Absorption, Biosensors, Waveguides, Absorbance, Beam propagation method, Cladding
J. Biomed. Opt. 13(5), 054049 (1 September 2008) doi:10.1117/1.2983663
TOPICS: Fiber optics, Optical tweezers, Particles, Video, Singular optics, Neurons, Mode locking, Objectives, Microscopes, Etching
Tord Hompland, Arne Erikson, Mikael Lindgren, Tore Lindmo, Catharina de Lange Davies
J. Biomed. Opt. 13(5), 054050 (1 September 2008) doi:10.1117/1.2983664
TOPICS: Collagen, Tissues, Second-harmonic generation, Optical fibers, Tumors, Anisotropy, Breast, Cancer, Polarization, Melanoma
J. Biomed. Opt. 13(5), 054051 (1 September 2008) doi:10.1117/1.2992132
TOPICS: Luminescence, Absorption, Scattering, Tissues, Fluorescence spectroscopy, Reflectivity, Spectroscopy, Double positive medium, Optical properties, Light scattering
Pinhas Ephrat, Lynn Keenlislide, Adam Seabrook, Frank Prato, Jeffrey Carson
J. Biomed. Opt. 13(5), 054052 (1 September 2008) doi:10.1117/1.2992131
TOPICS: Sensors, 3D image processing, Signal detection, Detector arrays, Reconstruction algorithms, Photoacoustic imaging, Imaging systems, Image restoration, 3D acquisition, Detection and tracking algorithms
J. Biomed. Opt. 13(5), 054053 (1 September 2008) doi:10.1117/1.2992129
TOPICS: Signal attenuation, Optical coherence tomography, Teeth, Dental caries, Light scattering, Statistical analysis, Binary data, Scattering, Signal detection, Biomedical optics
J. Biomed. Opt. 13(5), 054054 (1 September 2008) doi:10.1117/1.2993161
TOPICS: Cornea, Optical coherence tomography, Optical spheres, Glasses, Calibration, Reflectivity, Image resolution, Reflection, 3D image processing, In vivo imaging
Xin Qi, Yinsheng Pan, Zhilin Hu, Wei Kang, Joseph Willis, Kayode Olowe, Michael Sivak, Andrew Rollins
J. Biomed. Opt. 13(5), 054055 (1 September 2008) doi:10.1117/1.2993323
TOPICS: Image segmentation, Optical coherence tomography, Tissues, Endoscopy, Photomicroscopy, 3D image processing, Natural surfaces, Visualization, In vivo imaging, Colorectal cancer
Darya Orlova, Maxim Yurkin, Alfons Hoekstra, Valerii Maltsev
J. Biomed. Opt. 13(5), 054057 (1 September 2008) doi:10.1117/1.2992140
TOPICS: Light scattering, Blood, Refractive index, Scattering, Optical spheres, Luminescence, Laser scattering, Particles, Computer simulations, Molecules