Fluorescence diffuse optical tomography for free-space and multifluorophore studies

Anne Koenig; Lionel Hervé; Georges Gonon; Véronique Josserand; Michel Berger; Jean-Marc Dinten; Jerome Boutet; Philippe Peltié; Jean-Luc Coll; Philippe Rizo

doi:10.1117/1.3309738

1 January 2010 Fluorescence diffuse optical tomography for free-space and multifluorophore studies

Anne Koenig, Lionel Hervé, Georges Gonon, Véronique Josserand, Michel Berger, Jean-Marc Dinten, Jerome Boutet, Philippe Peltié, Jean-Luc Coll, Philippe Rizo

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Journal of Biomedical Optics, Vol. 15, Issue 1, 016016 (January 2010). https://doi.org/10.1117/1.3309738

Abstract

We present two major advances in preclinical fluorescence-enhanced diffuse optical tomography (fDOT) system and assess its performance. It is now possible to perform experiments without adaptation liquid or a glass plate over the animal, and our system is equipped with a filter wheel in order to discriminate two injected fluorophores. Evaluation carried out on characterization phantoms and in vivo on mice demonstrates enriched use of the system for biological studies on small animals.

©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Anne Koenig, Lionel Hervé, Georges Gonon, Véronique Josserand, Michel Berger, Jean-Marc Dinten, Jerome Boutet, Philippe Peltié, Jean-Luc Coll, and Philippe Rizo "Fluorescence diffuse optical tomography for free-space and multifluorophore studies," Journal of Biomedical Optics 15(1), 016016 (1 January 2010). https://doi.org/10.1117/1.3309738

Published: 1 January 2010

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