Graphics processing unit-based dispersion encoded full-range frequency-domain optical coherence tomography

Ling Wang; Bernd Hofer; Jeremy A. Guggenheim; Boris Považay

doi:10.1117/1.JBO.17.7.077007

11 July 2012 Graphics processing unit-based dispersion encoded full-range frequency-domain optical coherence tomography

Ling Wang, Bernd Hofer, Jeremy A. Guggenheim, Boris Považay

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Journal of Biomedical Optics, Vol. 17, Issue 7, 077007 (July 2012). https://doi.org/10.1117/1.JBO.17.7.077007

Abstract

Dispersion encoded full-range (DEFR) frequency-domain optical coherence tomography (FD-OCT) and its enhanced version, fast DEFR, utilize dispersion mismatch between sample and reference arm to eliminate the ambiguity in OCT signals caused by non-complex valued spectral measurement, thereby numerically doubling the usable information content. By iteratively suppressing asymmetrically dispersed complex conjugate artifacts of OCT-signal pulses the complex valued signal can be recovered without additional measurements, thus doubling the spatial signal range to cover the full positive and negative sampling range. Previously the computational complexity and low processing speed limited application of DEFR to smaller amounts of data and did not allow for interactive operation at high resolution. We report a graphics processing unit (GPU)-based implementation of fast DEFR, which significantly improves reconstruction speed by a factor of more than 90 in respect to CPU-based processing and thereby overcomes these limitations. Implemented on a commercial low-cost GPU, a display line rate of ∼21,000 depth scans/s for 2048 samples/depth scan using 10 iterations of the fast DEFR algorithm has been achieved, sufficient for real-time visualization in situ.

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Ling Wang, Bernd Hofer, Jeremy A. Guggenheim, and Boris Považay "Graphics processing unit-based dispersion encoded full-range frequency-domain optical coherence tomography," Journal of Biomedical Optics 17(7), 077007 (11 July 2012). https://doi.org/10.1117/1.JBO.17.7.077007

Published: 11 July 2012

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