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journal of biomedical optics
VOL. 8 · NO. 3 | July 2003
CONTENTS
IN THIS ISSUE
SPECIAL SECTION ON MULTIPHOTON MICROSCOPY (18)
Research Papers (14)
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SPECIAL SECTION ON MULTIPHOTON MICROSCOPY
Special Section Guest Editorial: Multiphoton Microscopy
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1594726
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Multiphoton excitation spectra in biological samples
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1583734
TOPICS: Sensors, Objectives, Signal attenuation, Microscopes, Multiphoton microscopy, Tunable lasers, Luminescence, Data acquisition, Solids, Nonlinear optics
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One- and two-photon fluorescence resonance energy transfer microscopy to establish a clustered distribution of receptor-ligand complexes in endocytic membranes
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1584444
TOPICS: Fluorescence resonance energy transfer, Microscopy, Luminescence, Contamination, Energy transfer, Phase modulation, Molecules, Algorithm development, Electronic filtering, Energy efficiency
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Illuminating protein interactions in tissue using confocal and two-photon excitation fluorescent resonance energy transfer microscopy
James Mills, James Stone, David Rubin, David Melon, David Okonkwo, Ammasi Periasamy, Gregory Helm
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1584443
TOPICS: Tissues, Fluorescence resonance energy transfer, Microscopy, Axons, Proteins, Confocal microscopy, Injuries, Traumatic brain injury, Tissue optics, Energy transfer
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Spectroscopic approach for monitoring two-photon excited fluorescence resonance energy transfer from homodimers at the subcellular level
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1584052
TOPICS: Fluorescence resonance energy transfer, Proteins, Luminescence, Spectroscopy, Green fluorescent protein, Optical filters, Two photon imaging, Microscopes, Fluorescence spectroscopy, Imaging spectroscopy
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Quantitative imaging of protein–protein interactions by multiphoton fluorescence lifetime imaging microscopy using a streak camera
Ramanujan Krishnan, Atsushi Masuda, Victoria Centonze, Brian Herman
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1577574
TOPICS: Fluorescence lifetime imaging, Proteins, Luminescence, Imaging systems, Fluorescence resonance energy transfer, Energy transfer, Streak cameras, Multiphoton fluorescence microscopy, Temporal resolution, Molecules
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Fluorescence resonance energy transfer determinations using multiphoton fluorescence lifetime imaging microscopy to characterize amyloid-beta plaques
Brian Bacskai, Jesse Skoch, Gregory Hickey, Racquel Allen, Bradly Hyman
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1584442
TOPICS: Fluorescence resonance energy transfer, Luminescence, Fluorescence lifetime imaging, Tissues, Proteins, Multiphoton fluorescence microscopy, Microscopes, Rhodamine, Multiphoton microscopy, Microscopy
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Analysis of histology specimens using lifetime multiphoton microscopy
Kevin Eliceiri, Ching-Hua Fan, Gary Lyons, John White
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1584053
TOPICS: Luminescence, Fluorescence lifetime imaging, Pulsed laser operation, Multiphoton microscopy, Tissues, Microscopy, Tissue optics, Sensors, Imaging systems, Veins
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Fluorescence lifetime imaging for the two-photon microscope: time-domain and frequency-domain methods
Enrico Gratton, Sophie Breusegem, Jason Sutin, Qiaoaio Ruan, Nicholas Barry
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1586704
TOPICS: Microscopes, Modulation, Luminescence, Signal to noise ratio, Phase shift keying, Sensors, Analog electronics, Electronics, Molecules, Data acquisition
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Two-photon interactions at single fluorescent molecule level
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1582180
TOPICS: Luminescence, Molecules, Glasses, Molecular interactions, Microscopes, Rhodamine, Confocal microscopy, Physics, Imaging spectroscopy, Imaging systems
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Multiphoton microscopy: an optical approach to understanding and resolving sulfur mustard lesions
Robert Werrlein, Janna Madren-Whalley
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1584687
TOPICS: Blistering agents, Cytoskeletons, Receptors, Tissues, Molecules, Multiphoton microscopy, Natural surfaces, Biomedical optics, Skin, Proteins
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Application of an ex ovo chicken chorioallantoic membrane model for two-photon excitation photodynamic therapy of age-related macular degeneration
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1577117
TOPICS: Content addressable memory, Blood vessels, Luminescence, Photodynamic therapy, Tissues, Blood, Tissue optics, Data modeling, Control systems, Diffusion
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Application of two-photon flash photolysis to reveal intercellular communication and intracellular Ca2+ movements
C. Soeller, M. D. Jacobs, P. Donaldson, M. B. Cannell, K. Jones, G. Ellis-Davies
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1582468
TOPICS: Calcium, Luminescence, Diffusion, Photolysis, Line scan image sensors, Data modeling, Spatial resolution, Confocal microscopy, Tissues, Reconstruction algorithms
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Mechanisms of membrane potential sensing with second-harmonic generation microscopy
Thomas Pons, Laurent Moreaux, Olivier Mongin, Mireille Blanchard-Desce, Jerome Mertz
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1581871
TOPICS: Second-harmonic generation, Electro optics, Microscopy, Molecules, Line scan image sensors, Switching, Polarization, Sensors, Electrodes, Hyper Rayleigh scattering
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High-resolution multiphoton tomography of human skin with subcellular spatial resolution and picosecond time resolution
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1577349
TOPICS: Luminescence, Skin, Tissues, In vivo imaging, Tissue optics, Second-harmonic generation, Femtosecond phenomena, Photons, Picosecond phenomena, Imaging systems
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Monte Carlo simulation of multiphoton fluorescence microscopic imaging through inhomogeneous tissuelike turbid media
Xiaoyuan Deng, Xiaosong Gan, Min Gu
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1577116
TOPICS: Scattering, Particles, Image resolution, Monte Carlo methods, Mie scattering, Multiphoton fluorescence microscopy, Luminescence, Image acquisition, Tissues, Seaborgium
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Characterizing point spread functions of two-photon fluorescence microscopy in turbid medium
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578644
TOPICS: Point spread functions, Scattering, Objectives, Luminescence, Two photon excitation microscopy, Water, Data modeling, Tissues, Optical spheres, Photons
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Compensation of spatial and temporal dispersion for acousto-optic multiphoton laser-scanning microscopy
Vijay Iyer, Bradley Losavio, Peter Saggau
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1580827
TOPICS: Dispersion, Prisms, Acoustics, Diffraction gratings, Acousto-optics, Spatial resolution, Diffraction, Mirrors, Multiphoton microscopy, Adaptive optics
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Research Papers
Metal-enhanced emission from indocyanine green: a new approach to in vivo imaging
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578643
TOPICS: Silver, Quartz, Metals, Luminescence, Particles, Indocyanine green, Quantum efficiency, Molecules, Atmospheric particles, Absorption
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Effects of biographical variables on cervical fluorescence emission spectra
Carrie Brookner, Urs Utzinger, Michele Follen, Rebecca Richards-Kortum, Dennis Cox, Edward Atkinson
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578642
TOPICS: Luminescence, Tissues, Collagen, Cervical cancer, Cervix, Fluorescence spectroscopy, Biological research, Algorithm development, Cancer, Diagnostics
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Light scattering from normal and dysplastic cervical cells at different epithelial depths: finite-difference time-domain modeling with a perfectly matched layer boundary condition
Dizem Arifler, Martial Guillaud, Anita Carraro, Anais Malpica, Michele Follen, Rebecca Richards-Kortum
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578640
TOPICS: Scattering, Light scattering, Finite-difference time-domain method, Refractive index, Mie scattering, Confocal microscopy, Cancer, Biopsy, Diagnostics, Dielectrics
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In vivo endoscopic tissue diagnostics based on spectroscopic absorption, scattering, and phase function properties
Philippe Thueler, Igor Charvet, Frédéric Bevilacqua, Michel Saint Ghislain, G. Ory, Pierre Marquet, Paolo Meda, Ben Vermeulen, Christian Depeursinge
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578494
TOPICS: Reflectivity, Tissue optics, Tissues, Monte Carlo methods, Absorption, Scattering, In vivo imaging, Inverse optics, Optical properties, Computer simulations
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Characterization of layered scattering media using polarized light measurements and neural networks
Kai Yong, Stephen Morgan, Ian Stockford, Mark Pitter
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578090
TOPICS: Absorption, Neural networks, Optical testing, Light scattering, Scattering, Polarization, Monte Carlo methods, Tissue optics, Photons, Scattering media
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Fiber dispersion in time domain measurements compromising the accuracy of determination of optical properties of strongly scattering media
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578088
TOPICS: Optical properties, Scattering, Dispersion, Tissue optics, Picosecond phenomena, Glasses, Diffusers, Time metrology, Scattering media, Laser scattering
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Spatial second-derivative image processing: an application to optical mammography to enhance the detection of breast tumors
Vivian Pera, Erica Heffer, Horst Siebold, Oliver Schütz, Sylvia Heywang-Köbrunner, Linda Götz, Anke Heinig, Sergio Fantini
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578496
TOPICS: Breast, Tumors, Mammography, Image enhancement, Blood vessels, Image processing, Absorption, Cancer, Biomedical optics, Image analysis
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Near-infrared transmittance pulse oximetry with laser diodes
Sonnia López Silva, María Dotor Castilla, Juan Silveira Martín
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578495
TOPICS: Oximetry, Sensors, Semiconductor lasers, Oxygen, Rhodamine B, Oximeters, Transmittance, Linear filtering, Signal processing, Blood
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Near-infrared thermo-optical response of the localized reflectance of intact diabetic and nondiabetic human skin
Shu-Jen Yeh, Omar Khalil, Charles Hanna, Stanislaw Kantor
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578641
TOPICS: Skin, Reflectivity, Temperature metrology, Sensors, Optical fibers, Tissue optics, Scattering, Absorption, Blood, Light emitting diodes
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Subsurface skin renewal by treatment with a 1450-nm laser in combination with dynamic cooling
Dilip Paithankar, Joan Clifford, Bilal Saleh, E. Victor Ross, Christina Hardaway, David Barnette
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1586703
TOPICS: Skin, Cryogenics, Injuries, Absorption, Biopsy, Collagen, Tissues, Monte Carlo methods, Thermal modeling, Laser scattering
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Embedded progressive-three-layered fiber long-period gratings for respiratory monitoring
Thomas Allsop, T. Earthrowl-Gould, David Webb, Ian Bennion
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578497
TOPICS: Sensors, Signal attenuation, Chest, Skin, Cladding, Temperature metrology, Refractive index, Optical fibers, Multiplexing, Silicon
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Modified laser speckle imaging method with improved spatial resolution
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578089
TOPICS: Blood circulation, Speckle, Spatial resolution, Blood, Speckle pattern, Laser speckle imaging, Temporal resolution, Doppler effect, Statistical analysis, Cerebral blood flow
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Speckle reduction in optical coherence tomography by frequency compounding
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1578087
TOPICS: Optical coherence tomography, Speckle, Light sources, Scattering, Beam splitters, Light scattering, Speckle pattern, Skin, Interferometry, In vivo imaging
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Texture analysis of optical coherence tomography images: feasibility for tissue classification
J. Biomed. Opt. 8(3), (1 July 2003) https://doi.org/10.1117/1.1577575
TOPICS: Tissues, Optical coherence tomography, Lung, Speckle, Image classification, Skin, Tissue optics, Statistical analysis, Eye, Ultrasonography
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