Breast dose reduction with organ-based, wide-angle tube current modulated CT

Wanyi Fu; Gregory M. Sturgeon; Greeshma Agasthya; Wiliam Paul Segars; Anuj J. Kapadia; Ehsan Samei

doi:10.1117/1.JMI.4.3.031208

4 August 2017 Breast dose reduction with organ-based, wide-angle tube current modulated CT

Wanyi Fu, Gregory M. Sturgeon, Greeshma Agasthya, Wiliam Paul Segars, Anuj J. Kapadia, Ehsan Samei

Author Affiliations +

Journal of Medical Imaging, Vol. 4, Issue 3, 031208 (August 2017). https://doi.org/10.1117/1.JMI.4.3.031208

Abstract

This study aimed to estimate the organ dose reduction potential for organ-dose-based tube current modulated (ODM) thoracic computed tomography (CT) with a wide dose reduction arc. Twenty-one computational anthropomorphic phantoms (XCAT) were used to create a virtual patient population with clinical anatomic variations. The phantoms were created based on patient images with normal anatomy (age range: 27 to 66 years, weight range: 52.0 to 105.8 kg). For each phantom, two breast tissue compositions were simulated: 50/50 and 20/80 (glandular-to-adipose ratio). A validated Monte Carlo program (PENELOPE, Universitat de Barcelona, Spain) was used to estimate the organ dose for standard tube current modulation (TCM) (SmartmA, GE Healthcare) and ODM (GE Healthcare) for a commercial CT scanner (Revolution, GE Healthcare) using a typical clinical thoracic CT protocol. Both organ dose and CTDI_vol-to-organ dose conversion coefficients (h factors) were compared between TCM and ODM. ODM significantly reduced all radiosensitive organ doses (p<0.01). The breast dose was reduced by 30±2%. For h factors, organs in the anterior region (e.g., thyroid and stomach) exhibited substantial decreases, and the medial, distributed, and posterior region saw either an increase of less than 5% or no significant change. ODM significantly reduced organ doses especially for radiosensitive superficial anterior organs such as the breasts.

Citation Download Citation

Wanyi Fu, Gregory M. Sturgeon, Greeshma Agasthya, Wiliam Paul Segars, Anuj J. Kapadia, and Ehsan Samei "Breast dose reduction with organ-based, wide-angle tube current modulated CT," Journal of Medical Imaging 4(3), 031208 (4 August 2017). https://doi.org/10.1117/1.JMI.4.3.031208

Received: 31 March 2017; Accepted: 6 July 2017; Published: 4 August 2017

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available