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4 August 2017 Breast dose reduction with organ-based, wide-angle tube current modulated CT
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This study aimed to estimate the organ dose reduction potential for organ-dose-based tube current modulated (ODM) thoracic computed tomography (CT) with a wide dose reduction arc. Twenty-one computational anthropomorphic phantoms (XCAT) were used to create a virtual patient population with clinical anatomic variations. The phantoms were created based on patient images with normal anatomy (age range: 27 to 66 years, weight range: 52.0 to 105.8 kg). For each phantom, two breast tissue compositions were simulated: 50/50 and 20/80 (glandular-to-adipose ratio). A validated Monte Carlo program (PENELOPE, Universitat de Barcelona, Spain) was used to estimate the organ dose for standard tube current modulation (TCM) (SmartmA, GE Healthcare) and ODM (GE Healthcare) for a commercial CT scanner (Revolution, GE Healthcare) using a typical clinical thoracic CT protocol. Both organ dose and CTDIvol-to-organ dose conversion coefficients (h factors) were compared between TCM and ODM. ODM significantly reduced all radiosensitive organ doses (p<0.01). The breast dose was reduced by 30±2%. For h factors, organs in the anterior region (e.g., thyroid and stomach) exhibited substantial decreases, and the medial, distributed, and posterior region saw either an increase of less than 5% or no significant change. ODM significantly reduced organ doses especially for radiosensitive superficial anterior organs such as the breasts.
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE) 2329-4302/2017/$25.00 © 2017 SPIE
Wanyi Fu, Gregory M. Sturgeon, Greeshma Agasthya, Wiliam Paul Segars, Anuj J. Kapadia, and Ehsan Samei "Breast dose reduction with organ-based, wide-angle tube current modulated CT," Journal of Medical Imaging 4(3), 031208 (4 August 2017).
Received: 31 March 2017; Accepted: 6 July 2017; Published: 4 August 2017

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