Improved surface-enhanced Raman scattering of insulin fibril templated colloidal gold nanoparticles on silicon

Chiung-Wen Hsieh; Pei-Ying Lin; Shuchen Hsieh

doi:10.1117/1.JNP.6.063501

12 March 2012 Improved surface-enhanced Raman scattering of insulin fibril templated colloidal gold nanoparticles on silicon

Chiung-Wen Hsieh, Pei-Ying Lin, Shuchen Hsieh

Author Affiliations +

Journal of Nanophotonics, Vol. 6, Issue 1, 063501 (March 2012). https://doi.org/10.1117/1.JNP.6.063501

Abstract

Insulin fibrils were used as a biotemplate to attach gold nanoparticles to silicon wafer surfaces for application as surface-enhanced Raman scattering (SERS) substrates. Gold nanoparticles (NP) attach to the insulin fibrils through electrostatic interactions forming chains of discreet NPs. A combination of 4-aminothiophenol and 4-Mercaptobenzoic acid were used as probe molecules to evaluate the Raman signal enhancement that was 10⁴ to 10⁶. The SERS signal was strongly enhanced on these surfaces due to the close inter-particle spacing of the patterned gold NPs.

Citation Download Citation

Chiung-Wen Hsieh, Pei-Ying Lin, and Shuchen Hsieh "Improved surface-enhanced Raman scattering of insulin fibril templated colloidal gold nanoparticles on silicon," Journal of Nanophotonics 6(1), 063501 (12 March 2012). https://doi.org/10.1117/1.JNP.6.063501

Published: 12 March 2012

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