Perifoveal retinal augmented reality on contact lenses

Abstract. We present an innovative augmented reality display to project information on the perifovea. Our system uses a contact lens embedding various diffractive optical elements (DOE) and switchable light sources. The DOEs are located at the iris periphery, keeping the visual axis free of any disturbance while allowing AR content projection onto the perifovea. The use of DOEs limits the quantity of displayable information for instance to some warning symbols but allows the design of more easily manufacturable elements. A proof of concept using a mock up eye (scale 2:1) to assess the impact of laser injection and mydriasis on image reconstruction quality is presented together with a video showing how the system operates dynamically.


Introduction
Technological advances have allowed information to be brought ever closer to the user (books, computers, laptops, smart phones) culminating with today's see through augmented reality (AR) systems. 1 In the last decade, advances in nanotechnology and flexible electronics have made it possible to consider a further step: the transition from AR near eye display to "contact lens display" (CLD). Several systems have been proposed to offer retinal AR (RAR). [2][3][4] We refer here, by CLD, to systems fully integrating the image generator into the contact lens. Other designs combining a contact lens with an eyewear integrating part of the image generator exist 5 but the alignment issues between the projector and the moving eye's pupil strongly limit their field of view (FOV).
Since the first single-pixel CLD from the Parviz group, 6,7 a number of papers have been published addressing the many challenges that need to be overcome to produce a fully functional CLD, such as power management (e.g. battery and energy harvesting 8 ), biocompatibility, mechanical, and electrical integration and display technology (e.g. using liquid crystal modulation 9 or micro or nano scaled light emitting components 10,11 ). If we consider for instance Chen et al's design, 10 according to the authors, "the minimal numbers of pixels for the nonfoveated and foveated displays are 15.38 and 3.20 megapixels" so far from what is achievable today (assuming a foveated LED array, this is the number of LEDS required to yield an angular resolution of 1' for a FOV of 100 deg, basically equating the number of LEDs to the number of photoreceptors).
However, the most puzzling and controversial aspect concerns the fact that the display is usually placed centered on the visual axis, which can strongly impact comfort and safety (e.g. reduced transparency, natural light scattering by the display, faulty display becoming opaque, and unwanted superimposition of the displayed information with the direction of gaze). Also, studies on multiple task performances and visual attention 12,13 suggest that visual information is processed along two parallels channels: focal vision (for form recognition and identification) and ambient vision (for visual guidance and motor control). Displaying the AR information on the fovea will thus increase the foveal cognitive load, which has been shown to have a negative impact on target detection. 14 This is why we decided to exploit the para and perifoveal areas of the retina and keep the pupil free of optical elements although this choice limits the AR capabilities and the nature of the information displayable on the retina.
The retina can be divided into several concentric zones with the fovea in the center (∼0 deg to 5 deg), surrounded by the parafoveal belt (∼5 deg to 8 deg) and the perifovea (∼8 deg to 18 deg). Visual performance (e.g., acuity and contrast sensitivity) tend to decrease away from the fovea due to lower cones and ganglion cell densities, but the parafovea can be used to determine the gist of a scene well enough for a categorization task. 15 Peripheral vision is also more sensitive to specific stimuli 16 and plays an important role in object detection. 17 In addition, the brain processes information coming from different regions of the visual field differently 18 and studies suggest that some perception tasks could begin in parafoveal vision in advance of foveal fixation (e.g. reading, processing of emotional visual scenes 19 ).
Projection of warning symbols on the peripheral retina is thus of interest as it could trigger a faster reaction, independently of where visual attention is directed. 20 In addition, some simple information such as warning symbols do not need to be displayed with high resolution, which is in agreement with the lower resolution of the perifovea. Placing the image generator off the visual axis to project onto the perifovea allows thus to address the issues of visual axis obstruction and, to some extent, manufacturability (since no high-resolution display is required). In this context, we present an innovative PRAR on a contact lens to project simple stimuli (e.g. warning symbols), on the peripheral retina. (By extension, we use here the term perifovea to encompass both the narrow parafovea and perifovea.) The PRAR design is presented in detail in the next section followed by an experimental validation at scale 2:1

Parafoveal Retinal Augmented Reality Imaging Principle
The principle of our perifoveal retinal AR device is as follows. The contact lens incorporates a ring (mainly covering the iris) made up of a plurality of DOEs (here 4) (cf. Fig. 1). The illumination of a DOE by a laser (also embedded in the contact lens) allows an image, generated by the holographic DOE, to be formed in the retinal plane. The illumination parameters (beam size, angle of incidence, etc.) are easily adjustable during the design phase.
To comply with the limited contact lens thickness that limits the superimposition of several optical elements, the VCSEL is placed alongside of the DOE and a light guide, made of two reflective annular layers (e.g., on both side of the lens), is used to guide the laser light to the DOE. This guide could also help in embedding additional optical functions, e.g., to focus the laser beam.
The internal diameter of the ring of DOEs is chosen to keep the pupil free of any optical element while facilitating image projection. As a result, DOE efficiency is impacted by the mydriasis. When the pupil is fully open, the whole of each DOE can be fully illuminated. When the pupil is partially closed, part of the light going through the DOE will be blocked. Because DOEs are usually made of periodic patterns, the hologram-generated figure is still imaged on the retina, the only difference is a reduction in the intensity and to some extent the resolution. The pupil diameter range to achieve good viewing will depend on several parameters such as the laser direction or the DOE pattern but for practical reasons, it should extend to at least 4 mm.
The choice of the light source depends on several constraints: DOEs generally require a coherent source, of limited divergence; the wavelength should ideally correspond to the sensitivity of the photoreceptors in the perifovea (e.g., 420 nm for rods or 534/564 nm for M/L cones); and the light source should fit within the lens. Practically, the choice of the optimum wavelength will depend on a number of factors. Rods are more sensitive that cones and their number increases toward the perifovea while the number of cones sharply decreases. On the other hand, longer wavelength may be preferred for safety reasons and components availability. Due to their coherence, directionality, and reduced size compared to LEDs, vertical-cavity surface-emitting lasers (VCSEL) are of particular interest. VSECLs emitting at 680 nm exist 21 but are difficult to obtain. For the present demonstration, we, therefore, used a semiconductor laser at 655 nm even though it does not correspond to the maximum of the photoreceptors sensitivity.
Another important aspect to consider is the eccentricity at which the image is projected since visual acuity strongly decreases with eccentricity. The visual axis makes an angle of approximately 3 deg to 5 deg horizontally and 2 deg to 3 deg vertically with respect to the eye's optical axis (cf. Fig. 1). In our design, we chose to project the holographic image 10 deg away from the fovea to avoid perturbing the central vision, so ∼12 deg to 15 deg from the eye's optical axis. At such eccentricity, the neural resolution is significantly reduced when compared to the fovea 22 so that the smallest details in the holographic image should be at least 48 μm large (which corresponds approximately to a visual acuity of 3 cpd), hence a relatively large retinal projection.

Optical Imaging System Design
As previously stated, image formation in our PRAR system may be affected by three factors. First, the laser light should be correctly guided to the DOE then to the targeted retinal zone. Second, since the image generator is off the visual axis, mydriasis will impact the image formation. Third, the DOE forms an image in the Fourier plane, so assuming the laser light is correctly focused to form an image in the retinal plane, accommodation may degrade the image.
To validate the concept experimentally, we created a scaled (2:1) eye model where the cornea is a 20D plano-convex lens (Thorlabs LA1131) and the crystalline lens a 10D biconvex lens (Thorlabs LB1676). Distances between cornea and pupil and lens and retina are respectively 6.6 and 32 mm. A diaphragm can be inserted in front of the crystalline lens (touching it) to assess the influence of the pupil on the image formation. In place of the retina, we used a digital camera (Sony alpha-Nex 5 with 5.07 μm pixel pitch). Our « eye model » is obviously very simple when compared to a real eye, for instance, we project the image on a flat sensor when the retina is curved but it allows reproducing the main elements, which are important for the proof of concept (pupil, crystalline lens, and sensor position).
Since the light source is embedded within the contact lens, the cornea can be considered not to affect light propagation. Indeed, the refractive power of the different interfaces before the crystalline lens will probably have little impact on beam propagation as the differences in refractive index are small and the VCSEL spot size is small (so the surfaces will show little curvature at this scale). The light from the laser will be focused only by the crystalline lens. However, such an eye would not be able to form a focused retinal image of the outside world. This is why we placed the "corneal" lens before the DOE to keep the eye emmetropic.
For the contact lens, in order to simulate a 750-μm thick scleral lens at scale 2:1, we used a one-inch diameter, 1.5-mm thick glass disk.
The laser (APCD-650-02-C2) was placed outside the lens and the beam injected into it through a small projection area. The laser module incorporates a lens that compensates for the fact that the position of the retina does not correspond to the focal plane of the lens. This optical power could be embedded within the guide or at the level of the DOE (but then making it more sensitive to mydriasis).
The light guide and diffractive elements were manufactured as follows. A 1.2-μm thick layer of S1813 (Shipley) photoresist was deposited on the glass disk by spin-coating. Multilevel phase DOEs were written into this layer with our massively parallel direct-write photo-plotter. 23 The DOE pattern was calculated using iterative Fourier-transform algorithms to produce a warning sign in the retinal plane. The DOEs (4 × 5 mm) were placed on an 11-mm diameter ring. The areas surrounding the DOEs are also fully exposed so that on development (303A Microposit), the DOEs were etched into the resist layer and the surrounding photoresist removed. The DOEs were designed using a three-stage IFTA based algorithm with an off-axis reconstruction image to eliminate disturbance by any residual zeroth order. They were manufactured at a resolution of 750 nm and with maximum etch depth of approximately 1010 nm. For the light guide, reflective gold layers were spluttered onto the top and bottom faces of the glass disk through laser cut, PET thin film stencils. The stencils protected the pupil area and the light injection area, keeping both free from spluttered gold. The sides of the glass disk were also protected, to prevent them from being covered by gold. The alignment and resolution of the gold area could be further improved using a photolithographic mask process rather than PET stencils. The thickness of reflective gold layers was a few tens of nanometers. These layers are currently fragile and could be protected or replaced by aluminum (more robust) or silver coating evaporation. Figure 2 shows the device as manufactured for the test. In this study, the written DOE reconstructs a danger road sign (i.e. the so-called "other danger" warning sign).
Finally, this element was mounted onto the scale model of the eye (cf. Fig. 3) to demonstrate the proof of concept. Fig. 2 View of the glass disk replacing the contact lens with the light guide and DOE (indicated by a red arrow). A golden reflective layer on either side of the disk helps guide the laser light toward the DOE. The rear layer (facing the eye) covers the iris. The front layer is thinner to allow coupling with the laser source so that by propagating in the guide, the light illuminates at the correct incidence the DOE located at the exit of the guide. The optimum injection angle for the laser light was calculated using Trace Pro (Fig. 4) and estimated to be 12 deg. The DOE was designed to produce an image 0.42-mm large on the retina (the user would thus see an image approximately as large as three full moons).

Optical Experimentation
The aim of this study was to validate the proof of concept, particularly the impact of the angle of injection, mydriasis, and lens power on the hologram reconstruction.
For the laser injection, based on the above embodiment, we obtained an optimal reconstruction image quality and efficiency [ Fig. 5(a)] at an angle of 12 deg with a tolerance of ∼5 deg corresponding to that predicted by our modeling. If the angle of injection departs from this range, the image becomes severely degraded, with reduced intensity and increased scattering [Figs. 5(b) and 5(c)] or simply not reconstructed at all. The image subtends 0.89 mm in the retinal plane (so slightly larger than expected (0.84 mm scale 2:1)). The width of the line making the triangle is approximately 220-μm large so the symbol could be easily perceived despite the poor acuity in the perifovea.
With respect to pupil size, and considering an optimum injection angle of 12 deg, pupil diameters larger or equal to 10 mm (scale 2:1) had no impact on the image quality [ Fig. 5(a)]. At 8 mm (scale 2:1), the image started to show degradation [increased scattering, less sharp image, Fig. 5(d)] and no image could be reconstructed with the 4 and 6 mm pupil (scale 2:1). Since our objective was to demonstrate the proof of concept, we did not apply any image quality metrics.
In terms of lens power, also reducing the lens power by 4D had a similar effect in terms of degraded image quality with a blurred image and increased scattering [ Fig. 5(e)]. This means that in the case of the accommodating eye, the image quality could be reduced without the image becoming unreadable.  In addition, we also tested the correct superimposition of the holographic image with a real scene (LogMar chart, Fig. 6). The image was obtained with a 12 mm pupil (scale 2:1) and illustrates the fact that even though part of the DOEs are illuminated by daylight, this does not induce any visual artefacts. The reduced image quality here is mainly due to the eye's aberrations.
The visualization (Fig. 7) presents a short video of the system operating dynamically. The scenario is a collision avoidance situation. A car driver (the angle of view is materialized by the camera angle) does not notice the presence of a pedestrian on a crossing. A separate system detects the potential risk of collision and sends a command to the RAR system, which activates a warning, immediately displayed on the retina and superimposed onto the scene. The driver cannot avoid the warning, whatever the direction of his/her gaze. When the situation no longer presents a risk, the laser switches off and the warning disappears. Such a RAR system could be used in real time. In our design, we assumed a scene observed at long range and thus there was no visual accommodation. In cases where the warning signal is displayed while the user is observing an object at a closer distance, for instance the driver watching his phone, the crystalline lens power would change by approximately 2D. This additional optical power would facilitate image formation by the DOE.

Discussion
In this paper, we have presented and scaled a very simple PRAR concept able to effectively solve the display and eye alignment issue, which is a limitation in the near-eye display (NED). Our system allows the superimposition onto the para or perifovea, of additional fixed symbols generated separately in the pupil periphery. Symbols are obtained from a DOE ring, overlapping partly the pupil and illuminated by embedded laser sources. Although, on our prototype we placed the DOEs around a circle, the position of the DOEs on the contact lens does not need to be rotationally symmetrical and could be adapted to the nasal or temporal part of the retina.
When compared to other solutions, the system presents several advantages. It requires no alignment with an external light source (unlike scanning laser-based systems 24 ) and it keeps  the pupil free from any display (e.g., unlike designs such as Shtukater's 11 ). Its main disadvantage is that the variety of AR contents is limited to a number of monochromatic images (though reconfigurable DOEs are possible). However, such information can be used efficiently to stimulate briefly the perifoveal area for some warning tasks. This could be of particular interest for head-up display devices where AR information may reduce the user's attentional resources available for the detection of external events (danger and alert).
Further describing the optical system, we have presented a proof of concept experimental setup at scale 2:1, taking into account the light guiding, mydriasis, and crystalline lens power. In our prototype, the PRAR system allows the correct projection (resolution, size) of AR contents in the perifovea for pupils larger or equal to 4 mm in diameter (scale 1:1). The fact that no image could be obtained for a smaller pupil was due to the decision to place the DOE far from the optical axis (2.5 mm, scale 1:1) to avoid visual disturbance but this could be further optimized. Even with very large pupil diameter (8 mm, scale 1:1) the presence of the DOE did not cause any visual artefacts.
In terms of apparent display size, this is set by the size of the retinal image, which can be easily adapted. In our set-up, we chose a retinal size corresponding to approximately three full moons as a compromise between something large enough to be seen and not too large that it would extend on to the fovea. Filling the entire FOV of the user is obviously achievable, whether by increasing the size of the image or by mosaicking the images from different DOEs but in contradiction with our objective.
In terms of dynamic functioning, the simplest way to switch the laser diode is to power it or not through induction. Similarly, for a system with several DOEs and associated laser sources, switching between different sources could be easily achieved using different carrier waves.
In terms of manufacturability, the integration of switchable laser sources or LEDs into contact lenses has already been demonstrated, for instance, by IMEC and University of Ghent 25 as well as the integration of diffractive elements. 26 Similarly, we have encapsulated a pointing laser into a scleral contact lens 27 as well as photodiodes. 28 A recurrent issue with smart contact lenses is the power supply. Here, the light sources could be remotely switched and powered by energy harvesting 8 (i.e., powered by an on-board RF antenna converting RF waves into currents triggering the on-board electronics thereby switching the light sources, as demonstrated in Ref. 27), or autonomous thanks to an embedded battery. 29 In a next step, the optics implemented here on a glass substrate, should be reduced to the correct scale and then implemented, for instance, on flexible substrates, such as thermoplastic polyurethane that can be molded to match the curvature of the contact lens. 30 Another potential extension would be to benefit from recent advances in DOEs on planar wave-guides, which could be used to miniaturize the near-to-eye diffractive optics 31 and to directly record the holographic element in the guide itself, keeping in mind that the pupil area should remain free and fully transparent.

Conclusion
A novel CLD was presented that has the advantage of letting the visual axis free of any element that could disturb vision. It is based on the integration into the lens of one or multiple diffractive optical elements (placed at the iris periphery) and associated light sources, and on an image projection away from the fovea. An application could be the projection of warning symbols on the peripheral retina to trigger a faster reaction. A proof of concept has been demonstrated at scale 2:1. This approach is part of the integration of increasingly complex functions on electronic contact lenses.