As the world develops, new and more advanced ways of transportation are invented; i.e. drones. Drones are used in several applications. However, the drone market does not utilize the need of medical emergency drones today, where these drones can be used to save countless lives in severe cases, e.g. sudden cardiac arrest. In case of cardiac arrest, defibrillators may save the life if it reaches the victims within short time. It raises the survival rate exponentially. Nonetheless, reaching the victims in a short period of time is challenging as the weight of the equipment is large. This work aims to design an autonomous drone that will be able to carry heavy payloads (portable medical equipment) while being fast and agile. The medical equipment/components are studied to choose the most fit for the proposed design in terms of efficiency and weight. The drone’s components are compared and studied in detail, allowing to choose the fittest motors, ESCs, frame, battery, and propellers. After which the quadcopter’s ability is expected to successfully achieve the objective of trying to save victim life in the city of Sharjah. In addition, the work includes a SolidWorks analysis to the design of the drone’s mechanical components to estimate the possibility of failure.