Research methods based on spectral analysis have powerful impact on development in many field of science. Signal spectrum can be a source of useful and important data. It enables to obtain information about physical and chemical properties of tested materials. This paper has been devoted to describe optical design for high resolution spectrometer, which is significant element of optical coherence tomography (OCT) systems. Designed spectrometer is working in visible range (450-830 nm). Czerny-Turner configuration enables to correcting astigmatism and coma aberration over full bandwidth. Moreover, spectrometer has uncomplicated construction. Merely, two mirrors and diffraction gratings allows to design low – cost spectrometer with satisfying optical properties. Spectrum detection has been realized using CMOS line scan sensors with 6144 pixels. It provides high speed and resolution of the system.
The main object of this research was to assess the ability to characterize the gold nanoparticles using optical modalities
like optical coherence tomography. Since the nanoparticles, especially gold one, have been very attractive for medical
diagnosis and treatment the amount of research activities have been growing rapidly. The nanoparticles designed for
different applications like contrast agents or drugs delivery change the optical features of tissue in different way.
Therefore, the expanded analysis of scattering optical signal may lead to obtain much more useful information about the
tissues health and the treatment efficiency. The noninvasive measurements of the concentration and distribution of the
nanoparticles, as well as their size in the media have been taken under consideration. For this purpose the polarization
sensitive optical coherence tomography system with spectroscopic analysis (PS-SOCT) has been designed and used. In
this contribution we are going to present the PS-SOCT measurement data obtained for the gold nanoparticles. The
measurements have been taken for the liquid (gold nanoparticles in water) samples changing the particles concentrations