Prof. Alexander P. Savitsky
at Fundamentals of Biotechnology of the RAS
SPIE Involvement:
Author | Instructor
Publications (52)

Proceedings Article | 7 March 2023 Presentation + Paper
Proceedings Volume 12378, 1237806 (2023)
KEYWORDS: Tumors, Magnetic resonance imaging, Tissues, Skin, In vivo imaging, Mixtures, Body composition, Contrast agents, Signal to noise ratio, Refractive index, Optical clearing

SPIE Journal Paper | 12 December 2022 Open Access
Alexander Konovalov, Vitaly Vlasov, Sergei Samarin, Ilya Soloviev, Alexander Savitsky, Valery Tuchin
JBO, Vol. 27, Issue 12, 126001, (December 2022)
KEYWORDS: Fluorescence, Fluorophores, Reconstruction algorithms, Picosecond phenomena, Light absorption, Absorption, Matrices, Image restoration, Fluorescence tomography, Data modeling

Proceedings Article | 9 March 2021 Presentation + Paper
Proceedings Volume 11641, 116410C (2021)
KEYWORDS: Optical clearing, Luminescence, Tumor growth modeling, Cancer, Tumors, Tissues, In vivo imaging, Tissue optics, Skin, Magnetic resonance imaging

Proceedings Article | 8 April 2020 Presentation
Daria Tuchina, Olga Sindeeva, Alexander Savitsky, Alexei Bogdanov, Valery Tuchin
Proceedings Volume 11363, 1136327 (2020)
KEYWORDS: Magnetic resonance imaging, Skin, Optical clearing, Tissue optics, In vivo imaging, Tissues, Optical coherence tomography, Light scattering, Scattering, Medicine

Proceedings Article | 6 April 2020 Presentation
Proceedings Volume 11363, 113630S (2020)
KEYWORDS: Tumors, Magnetic resonance imaging, Luminescence, In vivo imaging, Optical clearing, Skin, Tissues, Proteins, Magnetism, Confocal microscopy

Showing 5 of 52 publications
Proceedings Volume Editor (7)

Showing 5 of 7 publications
Conference Committee Involvement (12)
Laser Applications in Life Sciences
9 June 2010 | Oulu, Finland
Fluorescence In Vivo Imaging Based on Genetically Engineered Probes: From Living Cells to Whole Body Imaging IV
25 January 2009 | San Jose, California, United States
Small Animal Whole-Body Optical Imaging Based on Genetically Engineered Probes
21 January 2008 | San Jose, California, United States
Small Animal Whole-Body Optical Imaging Based on Genetically Engineered Probes
23 January 2007 | San Jose, California, United States
Genetically Engineered Probes for Biomedical Applications
24 January 2006 | San Jose, California, United States
Showing 5 of 12 Conference Committees
Course Instructor
SC039: Basic Principles of Microsecond Time-Resolved Photoluminescent Labeling Technology
Microsecond time-resolved photoluminescent labels are being used increasingly in immuno and DNA assays and diagnostics, biosensors and microbiochip, liquid chromatography and electrophoresis, microscopy, as well as drug detection and drug discover, cytotoxicity measurements (Eu-release), ecology, fingerprint detection, and long distance measurements in biological systems. Numerous and growing numbers of lanthanide chelates, room temperature phosphorescent labels provide dramatic improvements in sensitivity of assays, efficient background signal rejection, real-time measurements, high throughput screening, homogeneous and nonseparation formats of assays.
SC695: Optical in vivo Biosensing Based on Color Fluorescent Proteins
This course provides attendees with a basic working knowledge of fluorescent in vivo biosensors. Green fluorescent protein (GFP) was only the first of many types used for in vivo biosensing. Novel fluorescent proteins (nFP) from different sources comprise a rapidly growing arsenal of gene-based optical probes for numerous applications in biology, biotechnology, and medicine. This course concentrates <b>First</b>, on the systematization and classification of different nFP and major photophysical and chemical features of nFP. <b>Second</b>, on the principles of operation of molecular biosensors with fluorescent detection in living cells and animals. <b>Third</b>, on the application of nFP for drug design and screening. A survey of available genetic constructions and optical systems used for microscopic fluorescence detection as well as small animal whole-body imaging are included throughout the course.
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