The waveguide type biosensors for noninvasive glucose detection based on LSPR of silver nanoparticles were fabricated
by thermal diffusion in UV-irradiated photo-thermo-refractive (PTR) glasses and by ion-exchange method in sodiumborosilicate
glasses in water vapor atmosphere. The optical and structural properties of the obtained nanocomposites
were investigated. The D-glucose/D-galactose binding protein (GGBP) was chosen as a sensitive element of biosensor
and successable immobilized on top of PTR glass. The change in absorption spectra were judged due to the presence of
GGBP on the substrate surface.
Noble metal nanoparticles (MNPs) are widely used for fabrication of metal-dielectric plasmonic nanostructures with
optical properties attractive for applications. The MNPs embedded in a glass matrix are known to exhibit an intense color
related to the resonance oscillation of the free conduction electrons known as surface plasmon resonance (SPR). Silver
nanoparticles with diameter about 2 nm are shown to be formed in the subsurface layer of photothermorefractive (PTR)
glasses after electron beam irradiation with subsequent heat treatment. The type of MNPs depends on the composition of
the PTR glass. The size distribution and MNP concentration depend on irradiation dozes and heat treatment
temperatures. The report presents the technology of silver NP fabrication, experimental optical absorption spectra, low
frequency Raman scattering, and TEM images used for determination of the MNP size distribution, and simulation of
optical extinction spectra using generalized Mie model of light scattering.