Laser scanners are essential for scientific research, manufacturing, defense, and medical practice. Unfortunately, often times the speed of conventional laser scanners (e.g., galvanometric mirrors and acousto-optic deflectors) falls short for many applications, resulting in motion blur and failure to capture fast transient information. Here, we present a novel type of laser scanner that offers roughly three orders of magnitude higher scan rates than conventional methods. Our laser scanner, which we refer to as the hybrid dispersion laser scanner, performs inertia-free laser scanning by dispersing a train of broadband pulses both temporally and spatially. More specifically, each broadband pulse is temporally processed by time stretch dispersive Fourier transform and further dispersed into space by one or more diffractive elements such as prisms and gratings. As a proof-of-principle demonstration, we perform 1D line scans at a record high scan rate of 91 MHz and 2D raster scans and 3D volumetric scans at an unprecedented scan rate of 105 kHz. The method holds promise for a broad range of scientific, industrial, and biomedical applications. To show the utility of our method, we demonstrate imaging, nanometer-resolved surface vibrometry, and high-precision flow cytometry with real-time throughput that conventional laser scanners cannot offer due to their low scan rates.
We describe a real-time image processor that has enabled a new automated flow through microscope to screen cells in
flow at 100,000 cells/s and a record false positive rate of one in a million. This unit is integrated with an ultrafast optical
imaging modality known as serial time-encoded amplified microscopy (STEAM) for blur-free imaging of particles in
high-speed flow. We show real-time image-based identification and screening of budding yeast cells and rare breast
cancer cells in blood. The system generates E-slides (an electronic version of glass slides) on which particles of interest
are digitally analyzed.
Shared shuttle runs are an important factor of the microelectronics business ecosystem, allowing fabless semiconductor
companies to access advanced processes and supporting the development of new tools and processes. We report on the
creation and progress of a shared shuttle program for access to advanced silicon photonics optoelectronic platforms that
we expect will create a similar environment for the field of integrated photonics.