Dentin is a biological composite that forms the major bulk of tooth structure. Understanding the biomechanical response
of dentin structure to forces is essential to restore the loss of mechanical integrity associated with dentin loss during
disease or treatment procedures. Moiré interferometry is an optical interferometry based method, which allows wholefield,
real-time analysis of dental structures with high-sensitivity. The aim of this study was to investigate the
deformation gradients in dentin during function and subsequent to surface conditioning with bioactive biopolymeric
nanoparticle. Slab shaped dentin specimens were prepared and a customized loading jig was used to compressively load
the specimens from 10 N to 50 N. Specific regions of interest was chosen on the dentin specimens for strain analysis.
The digital moiré interferometry experiments showed a distinct deformation pattern in dentin in the direction
perpendicular to the dentinal tubules, which increased with increase in dentin loss. The dentin conditioned with
nanoparticles did not display marked increase in strain gradients with loads. The current photomechanical experiment
highlighted the impact of nanoparticle treatment to improve the mechanical integrity of dentin.