Microscale liquid handling based on electrowetting has been previously demonstrated by several groups. Such liquid
manipulation however is limited to control of individual droplets, aptly termed digital microfluidics. The inability to
form continuous channels thus prevents conventional microfluidic sample manipulation and analysis approaches, such as
electroosmosis and electrophoresis. In this paper, we discuss our recent progress on the development of electrowettingbased
virtual channels. These channels can be created and reconfigured on-demand and preserve their shape without
external stimulus. We also discuss recent progress towards demonstrating electroosmotic flows in such microchannels
for fluid transport. This would permit a variety of basic functionalities in this new platform including sample transport
and mixing between various functional areas of the chip.