Calibration methods of photometric spectral selection channels of biomedical in vivo photometer-spectrum analyzer which allow to measure absolute value of light fluxes at luminescence wavelength band (0.66 - 0.9 μm) during probe by wavelength 0.66 μm are presented. Three experimental calibration schemes for photometric channel are designed. Each channel consists of narrowband light filter, high sensitive pin-photoreceiver, amplifier block and ADC. Advantages and shortcomings of every scheme are discussed. Measurements of complete flux of light back scattered by the investigated sample and spectral analysis of this irradiation allow analyzing experimental data at quantitative level. The investigations of optical characteristics of biological tissues in vivo were made by means of calibrated photometer-spectrum analyzer. Tissues of volunteers belonging to different age with various diseases were investigated.
This paper is devoted to new prospects for ointment photophoresis. The clinical applications of ointment photophoresis are presented. Obtained results of clinical investigations are discussed. The goal of our study has been to corroborate some physical and pharmacological principles for photophoresis of selected ointments.
In this paper application of laser irradiation for medicine therapy is discussed. 168 patients aged 16 to 53 with acquired defects and deformities of the maxillofacial area and 23 patients aged 18 to 47 with posttraumatic optic nerve atrophy were observed. Also 56 children aged 5 to 12 with inborn maxillofacial deformities and inborn ptosises were observed. New method of laser therapy to enhance healing and results of clinical application of this method is represented.
A new technique of image processing, based on signal resolution in accordance with its own functions of transformation of Fourier-Hermite functions, is represented in this work. The present technique was used to estimate the structure of biotissue under research. Experimentally obtained images of a model medium and tissue of a man's ear (volunteer) in vivo were compared under conditions of coherent and non-coherent optical illumination. The obtained results and prospects of the present method developing in medical application are discussed. The possibility of the suggested method of image processing being an element of optical tomograph of new type is analyzed in this work.
In this paper the medical application of He-Ne lasers for the treatment of bronchial asthma is described. Research objective of this work was the development of a treatment method for children with bronchial asthman of heavy and medium-heavy forms, resistant to the base therapy, with the help of low-intensive laser radiation with wave length λ=0,63 μm.
The new technique of biological medium structure estimation based on optical diffraction filtration method is represented. Biological medium is considered as a superposition of cluster molecular structures. Depending on wavelength of probing optical radiation, during scattering the different particles participate which make a unique volume diffraction grating for each wavelength. The probing radiation characteristics variation allow to estimate the structure of the researched medium. Experiments on studying of coherent and not coherent optical radiation with biological media interaction have been carried out. The images of rabbits tissues, human tissues in vivo and fluoroplastic images were processed. For the first time scattered radiation image processing technique based on signal decomposition of the Hermite functions which are the eigenfunctions of Fourier transform was applied for such class of tasks. It has allowed to reveal in strongly scattered radiation a structural component. Estimating the characteristics of a structural component it is possible to receive geometrical parameters appropriate to probing radiation diffraction grating. The offered technique is perspective for studying biological molecular structures and creating tomographs of a new class.
Optical images of 'laser radiation, passed through a tissue of the rabbit (abdominal front wall and ear) in vivo, and passed through a model medium -- various thickness fluoroplastic disks have been received. New projection method of medical image processing based on signal expansion into series of eigenfunctions of the Fourier transform has been applied. The comparative analysis of results allowed detecting structural features of patterns of laser emission scattering by tissue.
In this work the research of influence of the laser radiation penetration depth in fluoroplastic on distribution of backscattered radiation intensity is carried out. The comparison of results received at intensity measurement of backscattered low intensive laser radiation in photometer and the geometrical sizes of the images of distribution of backscattered radiation intensity, registered CCD-camera is carried out. The well adjusted dependences are received. They show, that with growth of scatterer thickness the intensity of backscattered radiation increases, and the geometrical sizes of backscattered beam increases. On thickness, which depends on fluoroplastic optical characteristics and characteristics of initial radiation, the growth of the fixed characteristics ceases.
A biophotometer of new generation has been developed for diagnostics, medical treatment (including inflammatory process) and control over the process of recovery. The device includes an optical head with an adjustable angle of sight and processing block. The source ofprobing optical radiation is a semiconductor laser ? =0.635 µm, P=5 mW, which influences biological tissues non-invasively. The biophotometer gives an opportunity to obtain spectral coefficient of tissue reflection.