In the present communication an extensive study of lossless and lossy compression of laser confocal microscopy images
is conducted. For the lossy (irreversible) case, both objective and subjective results are given. It is shown that the
JPEG2000 compression standard outperforms all others, even the recently introduced HD Photo, in both the reversible
and irreversible cases. More specifically, the JPEG2000 lossless performance is approximately 15% better than the next
best image data compression algorithm tested (namely the PNG) and the JPEG2000 lossy compression objective
performance results are at least 3dB better than that of HD Photo or JPEG.