The Helmholtz-Zentrum Hereon is operating imaging beamlines for X-ray tomography (P05 IBL, P07 HEMS) for academic and industrial users at the synchrotron radiation source PETRA III at DESY in Hamburg, Germany. The high X-ray flux density and coherence of synchrotron radiation enables high-resolution in situ/operando/vivo tomography experiments and provides phase contrast, respectively. Large amounts of 3D/4D data are collected that are difficult to process and analyze. Here, we report on the application of machine learning for image segmentation including a guided interactive framework, multimodal data analysis (virtual histology), image enhancement (denoising), and self-supervised learning for phase retrieval.
The Helmholtz-Zentrum Hereon is operating several tomography end stations at the beamlines P05 and P07 of the synchrotron radiation facility PETRA III at DESY in Hamburg, Germany. Attenuation and phase contrast imaging techniques are provided as well as sample environments for in situ/operando/vivo experiments for applications in biology, medicine, materials science, etc. Very large and diverse data sets with varying spatiotemporal resolution, noise levels and artifacts are acquired which are challenging to process and analyze. Here we report on an active learning approach for the semantic segmentation of tomography data using a guided and interactive framework, and evaluate different acquisition functions for the selection of images to be annotated in the iterative process.