Assessing mechanical properties of tissue plays an important role in disease diagnosis and clinical examination. Here, we present a low resource and cost-effective method of using digital camera technologies to map mechanical properties of tissue, termed camera-based optical palpation. We applied this technique to breast cancer detection and burn scar assessment, validating its capability of generating high mechanical contrast between various tissue regions for clinical applications. We also implemented camera-based optical palpation in a smartphone, demonstrating its potential for telehealth applications in rural and remote areas, improving equity of access to optimal treatment for people all around the world.
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