The Medium Energy X-ray Telescope (ME), covering 5-30 keV, is one of the three main payloads of the Hard X-ray Modulation Telescope (HXMT). ME adopts an array of Si-PIN detectors. The detection area of one pixel is 56.25 mm<sup>2</sup> , and the total detection area is 952 cm<sup>2</sup> . The ME has a large active area while the pixel size is smaller. So the front-end electronics and forming electronics are realized by Application Specific Integrated Circuit (ASIC) chips. In this paper, we will describe the matching design of ME Si-PIN detector and ASIC, and the performance of the design. The energy response, temperature response, and dead time of a Two-Pixels Si-PIN detectors with the simplest readout electronics which is similar with ME, were tested on the Max Planck Institute for Extraterrestrial Physics PANTER X-ray test facility at Neuried by Munchen (Germany). The overall performance is quite similar to what was expected.