Dr. Bishnu P. Joshi
UMHS-Research Faculty at Univ of Michigan
SPIE Involvement:
Author
Area of Expertise:
Fluorescence Imaging , Clinical Imaging and Image processing , Preclinical and clinical validation, Histology, IHC, IF, Pharm/Tox, IND preparation , Preclinical Imaging , Developing Imaging agents , Phantom fabrication for validating optical imaging instruments
Profile Summary

My background is in developing optical imaging agents especially for early detection of cancer using targeted molecular imaging techniques, in vivo and in vitro phage display screening to investigate new drug for detection of various biomarkers, and assay development. I have diverse background in multidisciplinary areas such as organic chemistry, peptide/protein chemistry, combinatorial chemistry, peptidomimetics, small molecules and peptide libraries, bio-conjugation chemistry, optical and fluorescent dye selection for in vivo/in vitro imaging. I have been supporting peptide discovery and development teams in use of new imaging technology to facilitate translational research. I have been doing preclinical and clinical work with fluorescence imaging agents and custom designed endoscopes for the early detection of premalignant lesions in esophagus, colon and other cancer types.
Publications (5)

PROCEEDINGS ARTICLE | April 19, 2017
Proc. SPIE. 10049, Molecular-Guided Surgery: Molecules, Devices, and Applications III
KEYWORDS: Endoscopy, Tissues, Surgery, Luminescence, Molecules, Reflectivity, Endoscopes, Colorectal cancer, Colon, Current controlled current source

SPIE Journal Paper | March 12, 2012
JBO Vol. 17 Issue 02
KEYWORDS: In vivo imaging, Endoscopes, Target detection, Luminescence, Endoscopy, Colon, Tissues, Colorectal cancer, RGB color model, Cancer

PROCEEDINGS ARTICLE | March 2, 2012
Proc. SPIE. 8217, Endoscopic Microscopy VII
KEYWORDS: Target detection, Endoscopy, Cancer, Visualization, Tissues, Luminescence, Endoscopes, Colon, In vivo imaging, Absorption

PROCEEDINGS ARTICLE | March 1, 2012
Proc. SPIE. 8217, Endoscopic Microscopy VII
KEYWORDS: Endoscopy, Near infrared, Visualization, Tissues, Imaging systems, Luminescence, Endoscopes, Relays, Colon, In vivo imaging

PROCEEDINGS ARTICLE | February 22, 2011
Proc. SPIE. 7893, Endoscopic Microscopy VI
KEYWORDS: Target detection, Endoscopy, Optical filters, Tissues, Luminescence, Endoscopes, Image filtering, Colon, In vivo imaging, Mouse models

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