The focal ratio degradation effects on optical fibers, technically referred to as FRD, has been the subject of intense studies since the beginning of the use of optical fibers in the construction of instruments applied in astronomy. A number of studies attempt to relate FRD to light loss in the optical system and other studies attempt to qualify and quantify FRD as a function of the stress induced during assembly of the structures supporting the ends of the optical fibers. In this work, we present a large-scale study to characterize FRD in all the fibers that make up the cables of the FOCCoS, Fiber Optical Cable and Connectors System project. FOCCoS, has the main function of capturing the direct light from the focal plane of Subaru Telescope using 2400 optical fibers, each one with a microlens in its tip, and conducting this light through a route containing connectors to a set of four spectrographs. The optical fiber cable is divided in 3 different segments called Cable A, Cable B and Cable C. Multi-fibers connectors assure precise connection among all optical fibers of the segments, providing flexibility for instrument changes. Our study provides procedures and methods to analyze the effects of FRD on all cable segments for each type of termination involved. Special attention is devoted to the understanding of how angular deviations between the input surface of the fiber and the test beam can significantly influence the calculation of FRD in optical fibers.