Dr. Brian S. Sorg Profile

Dr. Brian S. Sorg

Program Director at

SPIE Involvement:

Scholarship Committee | Conference Program Committee | Author

Publications (26)

PROCEEDINGS ARTICLE | March 6, 2015

3D printed biomimetic vascular phantoms for assessment of hyperspectral imaging systems

Proc. SPIE. 9325, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue VII

KEYWORDS: Hyperspectral imaging, Tissues, Imaging systems, Image segmentation, Reflectivity, 3D printing, Printing, Yeast, Oximetry, 3D image processing

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SPIE Journal Paper | June 20, 2014

Forecasting new development of tumor areas using spatial and temporal distribution profiles of hemoglobin saturation in a mouse model

Ossandon, Miguel , Phatak, Dhananjay , Sorg, Brian , Kalpakis, Konstantinos

JMI Vol. 1 Issue 01

KEYWORDS: Tumors, Image segmentation, Mouse models, Cancer, Image registration, Mode conditioning cables, Tissues, Luminescence, Image analysis, Image transmission

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SPIE Journal Paper | June 5, 2012

Comparative evaluation of differential laser-induced perturbation spectroscopy as a technique to discriminate emerging skin pathology

Kozikowski, Raymond , Smith, Sarah , Lee, Jennifer , Castleman, William , Sorg, Brian , Hahn, David

JBO Vol. 17 Issue 06

KEYWORDS: Luminescence, Pathology, Skin, Laser induced fluorescence, Fluorescence spectroscopy, Laser spectroscopy, Spectroscopy, Tissues, Tissue optics, In vivo imaging

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PROCEEDINGS ARTICLE | February 16, 2012

In vivo spectral and fluorescence imaging microscopy of tumor microvessel blood supply and oxygenation changes following vascular targeting agent treatment

Proc. SPIE. 8222, Dynamics and Fluctuations in Biomedical Photonics IX

KEYWORDS: Hyperspectral imaging, Veins, Tumors, Blood, Microscopy, Luminescence, Arteries, Blood circulation, In vivo imaging, Animal model studies

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PROCEEDINGS ARTICLE | February 9, 2012

Delayed photolysis of liposomes: a strategy for the precision timing of bolus drug release using ex-vivo photochemical sensitization

Proc. SPIE. 8221, Optical Interactions with Tissue and Cells XXIII

KEYWORDS: Cancer, Data modeling, Tumors, Tissues, Blood, Toxicity, In vivo imaging, Tissue optics, Photolysis, In vitro testing

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PROCEEDINGS ARTICLE | February 8, 2011

Widefield in vivo spectral and fluorescence imaging microscopy of microvessel blood supply and oxygenation

Proc. SPIE. 7902, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IX

KEYWORDS: Veins, Cancer, Tumors, Tissues, Blood, Luminescence, Arteries, Oxygen, Blood circulation, In vivo imaging

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PROCEEDINGS ARTICLE | February 17, 2010

In vivo 3D and Doppler OCT imaging using electrothermal MEMS scanning mirrors

Proc. SPIE. 7594, MOEMS and Miniaturized Systems IX

KEYWORDS: Microelectromechanical systems, Actuators, Endoscopy, Mirrors, Cancer, Optical coherence tomography, Ear, In vivo imaging, Doppler tomography, 3D image processing

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SPIE Journal Paper | January 1, 2010

Spectral imaging reveals microvessel physiology and function from anastomoses to thromboses

Wankhede, Mamta , Agarwal, Nikita , Fraga-Silva, Rodrigo , deDeugd, Casey , Raizada, Mohan , Oh, Suh , Sorg, Brian

JBO Vol. 15 Issue 01

KEYWORDS: Tumors, Imaging spectroscopy, Blood circulation, Physiology, Imaging systems, Oxygen, Wound healing, Tissues, Blood, Hypoxia

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PROCEEDINGS ARTICLE | April 25, 2009

Spectral and fluorescence imaging of immune system and tissue response to an immunogenic agent

Proc. SPIE. 7313, Smart Biomedical and Physiological Sensor Technology VI

KEYWORDS: Tissues, Surgery, Imaging systems, Blood vessels, Polymers, Microscopy, Particles, Luminescence, Imaging spectroscopy, Control systems

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PROCEEDINGS ARTICLE | February 13, 2009

Spectral imaging of microvascular function in a renal cell carcinoma after treatment with a vascular disrupting agent

Proc. SPIE. 7182, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII

KEYWORDS: Hyperspectral imaging, Tumor growth modeling, Tumors, Tissues, Blood, Image resolution, Imaging spectroscopy, Oxygen, Radiotherapy, Blood circulation

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SPIE Journal Paper | January 1, 2008

Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors

Sorg, Brian , Hardee, Matthew , Agarwal, Nikita , Moeller, Benjamin , Dewhirst, Mark

JBO Vol. 13 Issue 01

KEYWORDS: Tumors, Oxygen, Tissues, Imaging spectroscopy, Hypoxia, Visualization, Imaging systems, Blood circulation, Blood, Microscopes

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PROCEEDINGS ARTICLE | February 21, 2006

Optical imaging measurements of oxygen transport fluctuations and gradients in tumor microvascular networks

Proc. SPIE. 6088, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IV

KEYWORDS: Optical imaging, Microscopes, Tumors, Tissues, Image acquisition, Oxygen, Optical testing, Hypoxia, Blood circulation, Image filtering

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SPIE Journal Paper | July 1, 2005

Hyperspectral imaging of hemoglobin saturation in tumor microvasculature and tumor hypoxia development

Sorg, Brian , Moeller, Benjamin , Donovan, Owen , Cao, Yiting , Dewhirst, Mark

JBO Vol. 10 Issue 04

KEYWORDS: Tumors, Oxygen, Hypoxia, Green fluorescent protein, Hyperspectral imaging, Blood, Tissues, Luminescence, Imaging systems, In vivo imaging

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PROCEEDINGS ARTICLE | March 23, 2005

Measurement of hemoglobin saturation in tumor microvasculature in preclinical models using hyperspectral imaging

Proc. SPIE. 5694, Spectral Imaging: Instrumentation, Applications, and Analysis III

KEYWORDS: Hyperspectral imaging, Microscopes, Tumor growth modeling, Green fluorescent protein, Tumors, Imaging systems, Blood, Luminescence, Oxygen, Hypoxia

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PROCEEDINGS ARTICLE | June 17, 2002

Tissue soldering with biodegradable polymer films: preliminary in-vivo compatibility test

Proc. SPIE. 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII

KEYWORDS: Tissues, Polymers, Skin, Laser welding, Control systems, In vivo imaging, Natural surfaces, Polymer thin films, Laser tissue interaction, In vitro testing

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PROCEEDINGS ARTICLE | May 21, 2001

Tissue soldering with biodegradable polymer films: in-vitro investigation of hydration effects on weld strength

Proc. SPIE. 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI

KEYWORDS: Tissues, Reflection, Polymers, Particles, Laser welding, Molybdenum, Natural surfaces, Polymer thin films, In vitro testing, Liquids

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SPIE Journal Paper | January 1, 2001

Improved vascular tissue fusion using new light-activated surgical adhesive on a canine model

McNally-Heintzelman, Karen , Sorg, Brian , Hammer, Daniel , Heintzelman, Douglas , Hodges, Diane , Welch, Ashley

JBO Vol. 6 Issue 01

KEYWORDS: Polymers, Proteins, Arteries, Adhesives, Laser tissue interaction, Tissues, Laser welding, Veins, Laser applications, Tissue optics

PROCEEDINGS ARTICLE | May 17, 2000

Biodegradable polymer thin film for enhancement of laser-assisted incision closure with an indocyanine-green-doped liquid albumin solder

Proc. SPIE. 3907, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X

KEYWORDS: Tissues, Reflection, Interfaces, Laser welding, Control systems, Semiconductor lasers, Natural surfaces, Polymer thin films, Laser tissue interaction, Liquids

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PROCEEDINGS ARTICLE | May 17, 2000

Improved laser-assisted vascular tissue fusion using solder-doped polymer membranes on a canine model

Proc. SPIE. 3907, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X

KEYWORDS: Proteins, Veins, Tissues, Polymers, Particles, Laser welding, Arteries, Semiconductor lasers, Adhesives, Laser tissue interaction

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PROCEEDINGS ARTICLE | April 28, 2000

Influence of optical absorption on urinary calculus threshold fluence and ablation efficiency during infrared laser ablation

Proc. SPIE. 3925, Biomedical Applications of Free-Electron Lasers

KEYWORDS: Laser ablation, Calculus, Infrared radiation, Absorbance, Laser damage threshold, Tissue optics, Free electron lasers, Calculi, Hard tissue optics, Absorption

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PROCEEDINGS ARTICLE | April 28, 2000

Free-electron laser tissue-soldering in vitro with an albumin solder

Proc. SPIE. 3925, Biomedical Applications of Free-Electron Lasers

KEYWORDS: Proteins, Tissues, Laser welding, Chromophores, Infrared radiation, Natural surfaces, Free electron lasers, Laser tissue interaction, In vitro testing, Absorption

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PROCEEDINGS ARTICLE | June 22, 1999

Precision dispensing of small volumes of albumin solder for laser-assisted wound closure

Proc. SPIE. 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX

KEYWORDS: Tissues, Laser welding, Semiconductor lasers, Bridges, Deposition processes, Molybdenum, Pulsed laser operation, Natural surfaces, Laser tissue interaction

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PROCEEDINGS ARTICLE | June 22, 1999

ICG-doped albumin protein solders for improved tissue repair

Proc. SPIE. 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX

KEYWORDS: Proteins, Tissues, Interfaces, Laser welding, Collagen, Semiconductor lasers, Solids, Natural surfaces, Laser tissue interaction, Liquids

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PROCEEDINGS ARTICLE | July 1, 1998

Optimal parameters for laser tissue soldering

Proc. SPIE. 3245, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII

KEYWORDS: Proteins, Tissues, Laser applications, Laser welding, Semiconductor lasers, Solids, Natural surfaces, Laser tissue interaction, Temperature metrology, Liquids

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PROCEEDINGS ARTICLE | August 18, 1997

Effects of compression on human skin optical properties

Proc. SPIE. 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II

KEYWORDS: Optical properties, Tissues, Scattering, Skin, Light scattering, Reflectivity, Optical testing, Transmittance, Tissue optics, Absorption

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PROCEEDINGS ARTICLE | June 16, 1997

Adaptable three-dimensional Monte Carlo modeling of imaged blood vessels in skin

Proc. SPIE. 2975, Laser-Tissue Interaction VIII

KEYWORDS: Data modeling, Tissues, Blood vessels, Skin, 3D modeling, Monte Carlo methods, Optical simulations, Tissue optics, Photon transport, Absorption

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