Prof. Cuixia Dai Profile

Prof. Cuixia Dai

at Shanghai Institute of Technology

SPIE Involvement:

Author

Publications (29)

Proceedings Article | 3 April 2024 Paper

Fast endoscopic OCTA imaging in mouse rectum using proximal scanning catheter

Zhikai Zhu, Cuixia Dai, Chen Niu, Zehua Guan, Wenjuan Wu

Proceedings Volume 12830, 128300E (2024) https://doi.org/10.1117/12.3002068

KEYWORDS: Endoscopy, Optical coherence tomography, Rectum, Tissues, Biological imaging, Imaging systems, Image registration, Biological samples, Reflection, Data acquisition

Read Abstract +

In recent years, endoscopic optical coherence tomography (OCT) has garnered widespread attention for non-invasive advantages in achieving three-dimensional visualization of internal organ cavities. In early-stage lesions, microvascular alterations occur before morphological tissue changes. Therefore, utilizing endoscopic OCTA for the detection of superficial capillaries serves as an adjunctive method for early disease screening. About ten years ago, the advantages of high-speed and stable operation of distal motorized catheters enabled the realization of endoscopic OCTA. However, the internal micro-motors lead to a larger outer diameter of distal imaging catheters, which restricts their clinical applicability for monitoring diseases in narrow luminal structures. Consequently, proximal imaging catheters, with their smaller size, have found its wide application in the commercial arena. However, due to limitations in external motor speed and susceptibility to external vibrations, there were no reports of proximal imaging catheters achieving endoscopic OCTA for a long time. Recently, we proposed the MB-scan scheme to mitigate the impact of external motion artifacts and achieve endoscopic OCTA based on a proximal catheter. The Singular Value Decomposition (SVD) algorithm was employed to eliminate static tissue information and obtain en face OCTA images of the murine rectum. In this study, we proposed a fast endoscopic OCTA using proximal scanning catheter based on B-scan scheme and a customed image registration algorithm. Image registration based on the similarity between adjacent B-scan frames was utilized to reduce the impact of external motor vibrations and improve image quality. Based on the registered images at the same scanning position, the speckle variance (SVAR) algorithm was employed to calculate variation of OCT intensity signals. Finally, en face OCTA images were generated. Collecting data from the mouse rectum, endoscopic OCTA images were obtained from the registered data using the SVAR algorithm.

Proceedings Article | 13 December 2023 Paper

Enhancement of multimodal imaging of rabbit eyes using optical clearing agents

Cuixia Dai, Yuchen Wang, Fukang Lv, Fengxian Du, Shuhao Fan, Wenjuan Wu

Proceedings Volume 12942, 129420A (2023) https://doi.org/10.1117/12.3006794

KEYWORDS: Optical coherence tomography, Tissues, Optical clearing, Biological imaging, Eye, Signal intensity, Transparency, Tissue optics, Photoacoustic microscopy

Read Abstract +

Proceedings Article | 27 November 2023 Poster + Paper

Capillary velocity measurement using microsphere imaging in optical coherence tomography angiography

Cuixia Dai, Huanhuan Yu, Changlu Zhang, Ruiming Kong, Fukang Lv, Teng Ma

Proceedings Volume 12770, 127703D (2023) https://doi.org/10.1117/12.2689083

KEYWORDS: Capillaries, Optical coherence tomography, Coherence imaging, Angiography, Velocity measurements, Optical imaging, Blood vessels, Detection and tracking algorithms, Biological imaging, Tissues

Read Abstract +

Optical coherence tomography angiography (OCTA) is a non-invasive, high-resolution imaging technique which visualizes capillary vasculatures. However, up to now, no accurate quantitation of capillary velocity based on OCTA images has been reported. Currently study of capillary velocity was substantially performed based on the empirical correlation curves between OCTA signals and blood flow velocity in respective OCT setups and OCTA algorithms. In this study, we proposed an accurate measurement of the capillary velocity in blood vessels using microbubble localization and tracking imaging. Based on localization and tracking of microbubble, motion of microbubble in the blood vessel was identified and parameters of vasculature such as the direction and velocity of capillary flow were subsequently obtained. In this prediction study, a flow phantom using the polystyrene microsphere and a cellulose tubing with the internal diameter of 300μm was used to simulate the flow in a single blood vessel. The flow velocity was set to be 2-6μL/min. In the experiment, 5% milk solution and microsphere suspension were injected into the cellulose tubing using a precision syringe pump. In OCT performance, B-scan imaging was set at a frame rate of 500 frames per second (fps). In each acquisition, 1000 effective frames were acquired, which corresponded to an ultrafast data acquisition of 2s. Speckle Variance (SV) algorithm was employed to remove background tissue signals and extract the flowing microsphere signals in OCT data. The center points of the microsphere were determined by identifying the local maxima of the cross-correlation coefficient. Additionally, the Kuhn-Munkres (KM) assignment algorithm was employed for the purpose of tracking microsphere. Distances between pairs of consecutive frames were then calculated for all microsphere. Ultimately the velocity magnitude map was generated. preliminary results on blood vessel phantom validated the feasibility of the proposed technique, which will be further performed in quantitation of capillary velocity in living tissues.

Proceedings Article | 27 November 2023 Poster + Paper

Fast endoscopic OCTA imaging using proximal scanning catheter

Huanhuan Yu, Teng Ma, Cuixia Dai, Chen Niu, Zehua Guan

Proceedings Volume 12770, 127703F (2023) https://doi.org/10.1117/12.2689123

KEYWORDS: Endoscopy, Optical coherence tomography, Visualization, Biological imaging, Tissues, Singular value decomposition, Signal intensity, Imaging systems, Image registration, Video surveillance

Read Abstract +

Proceedings Article | 18 July 2023 Paper

Vessel segmentation and quantification in ultra-wide-field OCTA images

Cuixia Dai, Xiyao Qiang, Xiangning Wang, Qiang Wu, Guogang Cao, Jiaqing Zhao

Proceedings Volume 12745, 1274508 (2023) https://doi.org/10.1117/12.2683002

KEYWORDS: Image segmentation, Blood vessels, Image processing, Vascular diseases, Machine learning, Retinal diseases, Retina, Neural networks, Network architectures

Read Abstract +

Proceedings Article | 29 March 2023 Open Access

Diagnosis of retinal diseases using the vision transformer model based on optical coherence tomography images

Zenan Zhou, Chen Niu, Huanhuan Yu, Jiaqing Zhao, Yuchen Wang, Cuixia Dai

Proceedings Volume 12601, 1260102 (2023) https://doi.org/10.1117/12.2665918

KEYWORDS: Transformers, Optical coherence tomography, Retinal diseases, Image classification, Technology, Classification systems, Eye, Retina

Read Abstract +

DOWNLOAD PAPER

Proceedings Article | 30 December 2022 Poster + Paper

OCT-measured retinal vasculature and intrinsic optical responses to transcorneal electrical stimulation

Zhengyang Liu, Chen Niu, Xueqing Ding, Liming Li, Cuixia Dai, Tianyang Zhao

Proceedings Volume 12316, 1231608 (2022) https://doi.org/10.1117/12.2642162

KEYWORDS: Optical coherence tomography, Visualization, Retina, Electrodes, Imaging systems, Angiography, Sodium, Signal attenuation, Reflectivity

Read Abstract +

Proceedings Article | 19 December 2022 Poster + Paper

Optical clearing agent enhanced multimodal photoacoustic microscopy and optical coherence tomography imaging of rabbit eyes

Yuchen Wang, Wei Qin, Fengxian Du, Xueqing Ding, Tianyang Zhao, Cuixia Dai

Proceedings Volume 12320, 123201S (2022) https://doi.org/10.1117/12.2642236

KEYWORDS: Optical coherence tomography, Optical clearing, Tissues, Signal detection, Coherence imaging, Eye, Absorption, Photoacoustic microscopy, Tissue optics, Optical imaging

Read Abstract +

Proceedings Article | 9 October 2021 Poster + Paper

Time serial development of optical performance of the myopic model mouse eyes

Qiang Wu, Tianyang Zhao, Xueqing Ding, Rui Qiu, Fengxian Du, Cuixia Dai, Yilei Shao, Meixiao Shen

Proceedings Volume 11900, 119002W (2021) https://doi.org/10.1117/12.2602191

KEYWORDS: Eye models, Optical coherence tomography, Fused deposition modeling, Zemax, Eye, Wavefront aberrations, Vitreous, Performance modeling, Data modeling, Biological research

Read Abstract +

Proceedings Article | 9 October 2021 Poster + Paper

Endoscope optical coherence tomography angiography using proximal scanning catheter

Song Yuting, Cuixia Dai, Gao Lei, Ruiming Kong, Teng Ma, Qi Zhang, Zhuoquan Chen, Guogang Cao

Proceedings Volume 11900, 119001E (2021) https://doi.org/10.1117/12.2601569

KEYWORDS: Optical coherence tomography, Microfluidics, Endoscopy, Angiography, Endoscopes, Tissues, Pancreatic cancer, Electronic filtering, Solids, Silicon

Read Abstract +

Proceedings Article | 9 October 2021 Poster + Paper

A convolutional neural network for screening and staging of diabetic retinopathy based on wide-field optical coherence tomography angiography

Qiang Wu, Cuixia Dai, Xiangning Wang, Fengxian Du, Guogang Cao, Bowen Dong, Lei Gao

Proceedings Volume 11900, 1190028 (2021) https://doi.org/10.1117/12.2601354

KEYWORDS: Angiography, Optical coherence tomography, Convolutional neural networks, Data modeling, Performance modeling, Image classification, Diagnostics, Photography, Neural networks, Eye models

Read Abstract +

Proceedings Article | 9 October 2021 Poster + Paper

FI nanoparticles enhanced multimodal near-infrared photoacoustic microscopy and optical coherence tomography imaging of rat choroid

Silue Zeng, Jingqin Chen, Chengbo Liu, Fengxian Du, Wei Qin, Lei Gao, Bowen Dong, Sisi Chen, Meixiao Shen, Cuixia Dai

Proceedings Volume 11900, 119002V (2021) https://doi.org/10.1117/12.2602180

KEYWORDS: Optical coherence tomography, Signal detection, In vivo imaging, Coherence imaging, Photoacoustic microscopy, Nanoparticles, Absorption, Optical imaging, Single mode fibers, Retina

Read Abstract +

Proceedings Article | 10 October 2020 Paper

Study of imaging performance of mouse eyes based on optical coherence tomography and ray tracing techniques

Cuixia Dai, Ruiming Kong, Lei Gao, Fengxian Du, Bowen Dong, Chunfeng Guo, Rui Qiu, Ailin Liu

Proceedings Volume 11553, 115530F (2020) https://doi.org/10.1117/12.2575418

KEYWORDS: Optical coherence tomography, Ray tracing, Eye, Ophthalmology, Zemax, Imaging systems, Diagnostics, Optical imaging, Eye models, Performance modeling

Read Abstract +

Proceedings Article | 20 November 2019 Paper

Imaging depth extension of optical coherence tomography by optical clearing method in vitro rabbit eye

Guoqiang Li, Ruiming Kong, Cuixia Dai, Wenjuan Wu, Rui Qiu, Hongwei Zhao, Ailin Liu, Xinmin Lu

Proceedings Volume 11190, 111900R (2019) https://doi.org/10.1117/12.2537551

KEYWORDS: Eye, Optical coherence tomography, Optical clearing, In vitro testing, Retina, Image segmentation, Tissues, Tissue optics, Backscatter, Image resolution

Read Abstract +

Proceedings Article | 19 February 2018 Paper

In vivo time-serial evaluation of laser-induced choroidal neovascularization in rats simultaneously using photoacoustic microscopy and optical coherence tomography

Lin Li, Cuixia Dai, Wenlu Liu, Fenghua Wang, Chuanqing Zhou

Proceedings Volume 10494, 1049469 (2018) https://doi.org/10.1117/12.2288989

KEYWORDS: Optical coherence tomography, In vivo imaging, Retina, Photoacoustic microscopy, Laser coagulation, Pathogens, Retinal scanning, Signal detection, Animal model studies, Reflectivity

Read Abstract +

Proceedings Article | 19 April 2017 Presentation

Quantified elasticity mapping of ocular tissue using acoustic radiation force optical coherence elastography (Conference Presentation)

Yueqiao Qu, Youmin He, Yi Zhang, Teng Ma, Jiang Zhu, Yusi Miao, Cuixia Dai, Ronald Silverman, Mark Humayun, Qifa Zhou, Zhongping Chen

Proceedings Volume 10053, 1005321 (2017) https://doi.org/10.1117/12.2250439

KEYWORDS: Tissue optics, Tissues, Acoustics, Coherence (optics), Elastography, Signal detection, Retina, Eye, Medical laser equipment, Laser applications

Read Abstract +

Proceedings Article | 17 February 2017 Paper

Volumetric vessel reconstruction method for absolute blood flow velocity measurement in Doppler OCT images

Li Qi, Jiang Zhu, Aneeka Hancock, Cuixia Dai, Xuping Zhang, Ron Frostig, Zhongping Chen

Proceedings Volume 10053, 1005331 (2017) https://doi.org/10.1117/12.2253309

KEYWORDS: Optical coherence tomography, Blood circulation, Doppler tomography, Arteries, Laser scattering, Image segmentation, Velocity measurements, Image analysis, Functional imaging, Biology, Doppler effect, Hemodynamics, Particles

Read Abstract +

Proceedings Article | 27 April 2016 Presentation

Miniature probe for mechanical properties of vascular lesions using acoustic radiation force optical coherence elastography (Conference Presentation)

Yueqiao Qu, Teng Ma, Youmin He, Mingyue Yu, Rui Li, Jiang Zhu, Cuixia Dai, Zhonglie Piao, K. Kirk Shung, Qifa Zhou, Zhongping Chen

Proceedings Volume 9710, 97100L (2016) https://doi.org/10.1117/12.2208390

KEYWORDS: Tissue optics, Elastography, Acoustics, Coherence (optics), Optical coherence tomography, Tissues, Transducers, Ultrasonics, Doppler tomography, Confocal microscopy

Read Abstract +

Proceedings Article | 8 March 2016 Paper

Automatic airway wall segmentation and thickness measurement for long-range optical coherence tomography images

Li Qi, Shenghai Huang, Andrew Heidari, Cuixia Dai, Jiang Zhu, Xuping Zhang, Zhongping Chen

Proceedings Volume 9697, 96973B (2016) https://doi.org/10.1117/12.2214605

KEYWORDS: Optical coherence tomography, Image segmentation, Endoscopy, Image processing, Edge detection, Tissues, Imaging systems

Read Abstract +

Proceedings Article | 20 November 2014 Paper

Dual illumination OCT at 1050nm and 840nm for whole eye segment imaging

Chuanqing Zhou, Shanhui Fan, Lin Qin, Cuixia Dai

Proceedings Volume 9268, 92682O (2014) https://doi.org/10.1117/12.2073620

KEYWORDS: Image segmentation, Eye, Optical coherence tomography, Imaging systems, Retina, Mirrors, Spectroscopy, In vivo imaging, Image resolution, Retinal scanning

Read Abstract +

SPIE Journal Paper | 18 September 2014 Open Access

Accommodation-induced variations in retinal thickness measured by spectral domain optical coherence tomography

Shanhui Fan, Yong Sun, Cuixia Dai, Haihua Zheng, Qiushi Ren, Shuliang Jiao, Chuanqing Zhou

JBO, Vol. 19, Issue 09, 096012, (September 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.9.096012

KEYWORDS: Eye, Optical coherence tomography, Retina, Distortion, Cornea, Statistical analysis, Image segmentation, Imaging systems, Optical calibration, Biomedical engineering

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 13 July 2012 Open Access

Simultaneous optical coherence tomography and autofluorescence microscopy with a single light source

Cuixia Dai, Xiaojing Liu, Shuliang Jiao

JBO, Vol. 17, Issue 8, 080502, (July 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.8.080502

KEYWORDS: Optical coherence tomography, Atrial fibrillation, Imaging systems, Light sources, Microscopy, Photons, Visible radiation, In vivo imaging, Tissues, Scattering

Read Abstract +

DOWNLOAD PAPER

Proceedings Article | 24 September 2011 Paper

In-vivo full depth of eye imaging spectral domain optical coherence tomography

Qiushi Ren, Chuanqing Zhou, Cuixia Dai, Shuliang Jiao, Peng Xi

Proceedings Volume 8135, 81351I (2011) https://doi.org/10.1117/12.893439

KEYWORDS: Image segmentation, Eye, Optical coherence tomography, In vivo imaging, Spectroscopy, Retina, Mirrors, Cornea, Imaging systems, Multichannel imaging systems

Read Abstract +

Proceedings Article | 1 September 2009 Paper

Design of a dynamically configurable OADM device

Cuixia Dai, Dean Liu, Qianmin Dong, Liren Liu

Proceedings Volume 7442, 74421I (2009) https://doi.org/10.1117/12.828844

KEYWORDS: Crystals, Holography, Volume holography, Electro optics, Crystallography, Wavelength division multiplexing, Electrodes, Crystal optics, Resistance, Lithium niobate

Read Abstract +

Proceedings Article | 20 September 2007 Paper

Electroholographic display with SLM

Yingjie Yu, Yannis Orphanos, Vivi Tornari, Cuixia Dai

Proceedings Volume 6695, 669515 (2007) https://doi.org/10.1117/12.735771

KEYWORDS: 3D image reconstruction, Holograms, Spatial light modulators, 3D displays, LCDs, 3D image processing, Holography, Digital holography, Computer generated holography, Displays

Read Abstract +

Proceedings Article | 20 September 2007 Paper

Study of photorefractive recording in Ce:Cu:LiNbO₃ on the wavelengths dependence

Cuixia Dai, Liren Liu, Yingjie Yu, Dean Liu

Proceedings Volume 6695, 66951I (2007) https://doi.org/10.1117/12.735327

KEYWORDS: Diffraction, Ultraviolet radiation, Crystals, Diffraction gratings, Electrons, Holography, Cerium, Copper, Switching, Laser crystals

Read Abstract +

Proceedings Article | 7 October 2005 Paper

Improvement of the nonvolatile holographic recording by application of external electric field

Liren Liu, De'an Liu, Cuixia Dai, Lijuan Wang, Yu Zhou

Proceedings Volume 5911, 59111E (2005) https://doi.org/10.1117/12.612712

KEYWORDS: Crystals, Holography, Photovoltaics, Ultraviolet radiation, Laser crystals, Diffraction, Holograms, Holography applications, Phase shifts, Surface plasmons

Read Abstract +

Proceedings Article | 22 October 2004 Paper

Vectorial solution of Kukhtarev equations for doubly doped crystals and optimal choice of recording directions in nonvolatile holographic storage

Liren Liu, Cuixia Dai, Yu Zhou, Lijuan Wang, Zhu Luan

Proceedings Volume 5560, (2004) https://doi.org/10.1117/12.558839

KEYWORDS: Crystals, Photovoltaics, Holography, Stereolithography, Refractive index, Lawrencium, Phase shift keying, Laser imaging, Laser crystals, Modulation

Read Abstract +

Proceedings Article | 22 October 2004 Paper

Study of time evolution of scattering noise magnification and optimization of nonvolatile holographic storage

Cuixia Dai, Dean Liu, Qianmin Dong, Liren Liu, Zhu Luan

Proceedings Volume 5560, (2004) https://doi.org/10.1117/12.557879

KEYWORDS: Scattering, Crystals, Signal to noise ratio, Laser scattering, Holography, Electrons, Ultraviolet radiation, Laser crystals, Picosecond phenomena, Light scattering

Read Abstract +

Showing 5 of 29 publications

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Keywords/Phrases

Search In:

Publication Years