Mr. Curry P. Bucht Profile

Curry P. Bucht

at St Erik Eye Hospital

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Author

Publications (5)

Proceedings Article | 3 March 2010 Paper

Fully automated corneal endothelial morphometry of images captured by clinical specular microscopy

Curry Bucht, Per Söderberg, Göran Manneberg

Proceedings Volume 7550, 75501E (2010) https://doi.org/10.1117/12.849255

KEYWORDS: Cornea, Microscopy, Fourier transforms, Error analysis, Image enhancement, Statistical analysis, Microscopes, Software development, MATLAB, Image analysis

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The corneal endothelium serves as the posterior barrier of the cornea. Factors such as clarity and refractive properties of the cornea are in direct relationship to the quality of the endothelium. The endothelial cell density is considered the most important morphological factor of the corneal endothelium. Pathological conditions and physical trauma may threaten the endothelial cell density to such an extent that the optical property of the cornea and thus clear eyesight is threatened. Diagnosis of the corneal endothelium through morphometry is an important part of several clinical applications. Morphometry of the corneal endothelium is presently carried out by semi automated analysis of pictures captured by a Clinical Specular Microscope (CSM). Because of the occasional need of operator involvement, this process can be tedious, having a negative impact on sampling size. This study was dedicated to the development and use of fully automated analysis of a very large range of images of the corneal endothelium, captured by CSM, using Fourier analysis. Software was developed in the mathematical programming language Matlab. Pictures of the corneal endothelium, captured by CSM, were read into the analysis software. The software automatically performed digital enhancement of the images, normalizing lights and contrasts. The digitally enhanced images of the corneal endothelium were Fourier transformed, using the fast Fourier transform (FFT) and stored as new images. Tools were developed and applied for identification and analysis of relevant characteristics of the Fourier transformed images. The data obtained from each Fourier transformed image was used to calculate the mean cell density of its corresponding corneal endothelium. The calculation was based on well known diffraction theory. Results in form of estimated cell density of the corneal endothelium were obtained, using fully automated analysis software on 292 images captured by CSM. The cell density obtained by the fully automated analysis was compared to the cell density obtained from classical, semi-automated analysis and a relatively large correlation was found.

Proceedings Article | 18 February 2009 Paper

Fully automated corneal endothelial morphometry of images captured by clinical specular microscopy

Curry Bucht, Per Söderberg, Göran Manneberg

Proceedings Volume 7163, 716315 (2009) https://doi.org/10.1117/12.816850

KEYWORDS: Fourier transforms, Cornea, Image analysis, Image filtering, Binary data, Microscopy, Image enhancement, Error analysis, Bandpass filters, Algorithm development

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Proceedings Article | 25 February 2008 Paper

The impact of horizontal offset of the cornea during corneal specular microscopy

Curry Bucht, Per Söderberg, Göran Manneberg

Proceedings Volume 6844, 684413 (2008) https://doi.org/10.1117/12.779573

KEYWORDS: Cornea, Polymethylmethacrylate, Image analysis, Error analysis, Refractive index, Microscopy, Fourier transforms, Microscopes, In vivo imaging, Eye

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Proceedings Article | 5 March 2007 Paper

Recording the diffraction pattern reflected from corneal endothelium

Curry Bucht, Per Söderberg, Göran Manneberg

Proceedings Volume 6426, 642610 (2007) https://doi.org/10.1117/12.717478

KEYWORDS: Diffraction, Cornea, Diffraction gratings, Reflection, Far-field diffraction, Collimation, Lenses, Beam splitters, Helium neon lasers, Interfaces

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Proceedings Article | 7 March 2006 Paper

A model for corneal endothelial morphometry by diffraction

Curry Bucht, Per Söderberg, Göran Manneberg

Proceedings Volume 6138, 61380O (2006) https://doi.org/10.1117/12.660023

KEYWORDS: Diffraction, Modulation, Mathematical modeling, Fourier transforms, Cornea, Computer programming languages, Computer programming, MATLAB, Computer simulations, Eye

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