Dr. D. Michael McMullan Profile

Dr. D. Michael McMullan

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 25 February 2020 Presentation + Paper

Optical spectroscopy to assess muscle oxygenation in infants undergoing extracorporeal life support

Kenneth Schenkman, Andrew Mesher, D. Michael McMullan, Wayne Ciesielski, Faith Ross, Lorilee S. Arakaki

Proceedings Volume 11215, 112150R (2020) https://doi.org/10.1117/12.2553230

KEYWORDS: Optical spectroscopy, Heart, Blood, Tissues, Surgery, Tissue optics, Data acquisition, Oxygen, Hypoxia

Read Abstract +

Extracorporeal life support (ECLS) is used in intensive care units (ICUs) as heart-lung bypass for critically ill patients to support either inadequate heart or lung function. Decisions to discontinue ECLS are typically based on clinical judgment and patient trajectory during trial-off support. We investigated an optical measurement of muscle oxygenation (MOx) as an indicator for adequacy of circulatory function during trials-off ECLS. Clinicians were queried prior to trial-off as to whether the patient was deemed: ready, might be ready, or not likely ready to discontinue ECLS. MOx was determined using an optical analysis developed in our laboratory. Optical spectra were acquired from infants using a fiber-optic probe affixed to the arm or leg. Five infants were studied during 6 trials-off ECLS. Mean initial MOx was 96.6+/-8.5% (n=6). In trials resulting in discontinuation of ECLS, MOx was > 94%. In those remaining on ECLS, MOx was lower during the trial off at all time points. Mean MOx trended lower (75.1+/-23.5%), in the first 6 minutes for those not removed from ECLS, compared with those for whom ECLS was subsequently discontinued (97.2+/-3.8%). Lactate trended higher in subjects remaining on ECLS (3.4+/-0.8) compared with those removed from support (1.7+/-0.7). Clinician predictions prior to trial-off did not correlate with ultimate decision for discontinuing ECLS. Although preliminary, we believe that MOx may be useful to assist in objectively assessing adequacy of circulatory function and may be helpful in the early determination of readiness for discontinuation of ECLS.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years