The frangibility and vulnerability of Karst ecological environment have induced a series of major ecological
environmental problems in Guizhou province, China. So, it is important to study the Karst landscape pattern in Guizhou
province. In this paper, quantitative remote sensing inversion model and spatial analysis have been selected to study
Karst landscape spatial pattern of Qingzhen city in Guizhou. The results show that the topological relations between
different landscape patterns are very complexity and Qingzhen city has characteristics of high degree Karst landscape
fragmentation and fragile Karst environment. Shrub-tree is a dominant landscape type while severe rock desertification
landscape has strong interference characteristics.