Dr. Daniel M. de Bruin
Research Associate at Amsterdam UMC
SPIE Involvement:
Area of Expertise:
Optical Coherence Tomography (OCT) , Clinical applications of functional OCT , Cancer Imaging , Optical Biopsy , Optical Diagnostics , Business Development
Profile Summary

Currently, I'm employed as a clinical postdoctoral researcher at the departments of Urology and Biomedical Engineering & Physics of the AMC. I initiate new research that will ultimately result in a minimal invasive optical biopsy tool that allows diagnosis of (epithelial) cancer

From 2007 until 2011, I worked as a Ph.D. student at the department of biomedical engineering & physics (BMEP) at the Academic Medical Center (AMC). My projects revolved around optical coherence tomography (OCT), a new clinical imaging technique that enables minimal invasive optical biopsy. Besides understanding and engineering OCT technology, we partially leaped the gap that existed between new optical clinical imaging technologies and the everyday clinical reality. This resulted in new and successful collaborations between our department and departments such as Urology, Cardiology, Surgery and Radiotherapy within the AMC. Moreover, other Amsterdam based hospitals such as the Dutch Cancer Institute (NKI) and the Vrije Universiteit medical center (VUmc) are involved in our projects as well.
Publications (27)

SPIE Journal Paper | 3 April 2020
JBO Vol. 25 Issue 04
KEYWORDS: Optical coherence tomography, Signal attenuation, Tissues, Scattering, Tissue optics, Light scattering, Skin, Optical properties, Absorption, Cancer

Proceedings Article | 1 April 2020
Proc. SPIE. 11362, Clinical Biophotonics

Proceedings Article | 6 March 2020
Proc. SPIE. 11212, Therapeutics and Diagnostics in Urology 2020
KEYWORDS: Safety, Tissues, Surgery, Laser ablation, Prostate, Standards development

Proceedings Article | 18 March 2019
Proc. SPIE. 10956, Medical Imaging 2019: Digital Pathology
KEYWORDS: Principal component analysis, Cancer, Convolutional neural networks, Tumors, Tissues, Lung, Mass spectrometry, Image classification, Convolution, Bladder

SPIE Journal Paper | 9 August 2018
JBO Vol. 23 Issue 08
KEYWORDS: Optical coherence tomography, Tissues, Prostate, Signal attenuation, Prostate cancer, Visualization, Tissue optics, Inflammation, Quantitative analysis, Visual analytics

Showing 5 of 27 publications
Conference Committee Involvement (3)
American Urological Association Annual Meeting
16 May 2014 |
The International Symposium on Focal Therapy and Imaging in Prostate and Kidney Cancer
29 May 2013 |
Oncology Graduate School Amsterdam
24 November 2010 |
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