Dr. David H. Kessel Profile

Imran Rizvi, Shubhankar Nath, Girgis Obaid, Huang-Chiao Huang, Mans Broekgaarden, Anne-Laure Bulin, Sriram Anbil, Utkan Demirci, David Kessel, Tayyaba Hasan

Proceedings Volume 10476, 1047604 (2018) https://doi.org/10.1117/12.2290472

KEYWORDS: Photodynamic therapy, 3D modeling, Resistance, Tumor growth modeling, Pancreatic cancer, Cancer, Oncology, 3D acquisition, Ovarian cancer, Therapeutics

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Proceedings Article | 12 February 2018 Presentation + Paper

Photodynamic therapy: the role of paraptosis

David Kessel, Won-Jin Cho, Hyeong-Reh Kim

Proceedings Volume 10476, 1047602 (2018) https://doi.org/10.1117/12.2291997

KEYWORDS: Photodynamic therapy, Cell death, Proteins, Head, Neck, Lung cancer, Cancer, Tissues, Pharmacology, Pathology

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Proceedings Article | 8 February 2017 Presentation + Paper

Sequential vs. simultaneous photokilling by mitochondrial and lysosomal photodamage

David Kessel

Proceedings Volume 10047, 1004702 (2017) https://doi.org/10.1117/12.2251207

KEYWORDS: Photodynamic therapy, Cell death, Mouse models, Process modeling, Cancer, Calcium, Proteins, Light sources, Absorbance, Photosensitizer targeting, Tissue optics, Tumors, Lung cancer, Transparency

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Proceedings Article | 1 March 2016 Presentation + Paper

Mechanistic studies on a sequential PDT protocol

David Kessel

Proceedings Volume 9694, 969402 (2016) https://doi.org/10.1117/12.2214924

KEYWORDS: Photodynamic therapy, Proteins, Tumors, Oxygen, Luminescence, Photosensitizer targeting, Microscopy, Data conversion, Calcium, Pharmacology

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Proceedings Article | 2 March 2015 Paper

Promotion of PDT efficacy by low-dose lysosomal photodamage

David Kessel

Proceedings Volume 9308, 930802 (2015) https://doi.org/10.1117/12.2076772

KEYWORDS: Imaging systems, Linear filtering, Sensors, Photodynamic therapy, Weapons of mass destruction, Digital imaging, Detection and tracking algorithms, Channel projecting optics, Convolution, Matrices

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Proceedings Article | 14 April 2014 Paper

Increased efficacy of photodynamic therapy via sequential targeting

David Kessel, Neha Aggarwal, Bonnie Sloane

Proceedings Volume 8931, 893102 (2014) https://doi.org/10.1117/12.2042421

KEYWORDS: Photodynamic therapy, Proteins, Luminescence, Signal generators, Photosensitizer targeting, 3D modeling, Oxygen, Tumors, Signal processing, Iron

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Proceedings Article | 22 February 2013 Paper

Effects of oxygenation on PDT efficacy as a function of reactive oxygen species formation

David Kessel, Michael Price

Proceedings Volume 8568, 856802 (2013) https://doi.org/10.1117/12.2004560

KEYWORDS: Oxygen, Photodynamic therapy, Absorbance, Luminescence, Photochemistry, Cancer, Hypoxia, Nitrogen, Gases, Oxidation

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Proceedings Article | 14 February 2012 Paper

PDT: loss of autophagic cytoprotection after lysosomal photodamage

David Kessel, Michael Price

Proceedings Volume 8210, 821002 (2012) https://doi.org/10.1117/12.905286

KEYWORDS: Photodynamic therapy, Luminescence, Oxygen, Cell death, Photosensitizer targeting, Environmental sensing, Microscopy, Pharmacology, Medicine, Oxidation

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Proceedings Article | 8 February 2011 Paper

Biological consequences of PDT: tying up the loose ends

David Kessel, Michelle Andrzejak, Michael Price

Proceedings Volume 7886, 788602 (2011) https://doi.org/10.1117/12.876209

KEYWORDS: Photodynamic therapy, Oxygen, Cell death, Luminescence, Leukemia, Tumors, Proteins, Control systems, Tissues, In vitro testing

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SPIE Journal Paper | 1 September 2010 Open Access

On the use of fluorescence probes for detecting reactive oxygen and nitrogen species associated with photodynamic therapy

Michael Price, David Kessel

JBO, Vol. 15, Issue 05, 051605, (September 2010) https://doi.org/10.1117/12.10.1117/1.3484258

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Proceedings Article | 3 March 2010 Paper

Effects of PDT on the endocytic pathway

David Kessel

Proceedings Volume 7551, 755102 (2010) https://doi.org/10.1117/12.840530

KEYWORDS: Photodynamic therapy, Plasma, Luminescence, Electron microscopy, Camera shutters, Leukemia, Signal processing, Kidney, Cell death, Data modeling

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Proceedings Article | 13 July 2009 Paper

Downregulation of the autophagy protein ATG-7 correlates with distinct sphingolipid profile in MCF-7 cells sensitized to photodamage

Duska Separovic, Ameeta Kelekar, Adi Tarca, Jacek Bielawski, David Kessel

Proceedings Volume 7380, 73805M (2009) https://doi.org/10.1117/12.827261

KEYWORDS: Photodynamic therapy, Stereolithography, Proteins, Control systems, Cancer, Molecules, Statistical analysis, Medicine, Cell death, Breast cancer

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Proceedings Article | 13 July 2009 Paper

Photodynamic therapy: first responses

David Kessel, Michael Price

Proceedings Volume 7380, 738009 (2009) https://doi.org/10.1117/12.822140

KEYWORDS: Photodynamic therapy, Cell death, Proteins, Oxygen, Luminescence, Tumors, Leukemia, Microscopy, Camera shutters, Pharmacology

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Proceedings Article | 18 February 2009 Paper

The role of reactive oxygen species in PDT efficacy

Michael Price, Nakaiya Okan-Mensah, Ann Marie Santiago, David Kessel

Proceedings Volume 7164, 716402 (2009) https://doi.org/10.1117/12.810231

KEYWORDS: Photodynamic therapy, Oxygen, Luminescence, Cell death, Proteins, Medicine, Leukemia, Carbon dioxide, Tumors, Camera shutters

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Proceedings Article | 8 February 2008 Paper

Promotion of PDT efficacy by HA14-1

David Kessel, Michael Price, Kelly Haagenson

Proceedings Volume 6845, 684502 (2008) https://doi.org/10.1117/12.758836

KEYWORDS: Photodynamic therapy, Luminescence, Cell death, Proteins, Oxygen, Toxicity, Medicine, NOx, Hydrogen, Tissues

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Proceedings Article | 9 February 2007 Paper

PDT: death pathways

David Kessel

Proceedings Volume 6427, 642702 (2007) https://doi.org/10.1117/12.702441

KEYWORDS: Photodynamic therapy, Cell death, Proteins, Luminescence, Tumors, Microscopy, Camera shutters, Plasma, Tissues, Cancer

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Proceedings Article | 6 March 2006 Paper

Ceramide accumulation after photosensitization is absent after the Bcl-2 Inhibitor HA14-1

Duska Separovic, Shouye Wang, Kentaro Hanada, David Kessel

Proceedings Volume 6139, 61390E (2006) https://doi.org/10.1117/12.657692

KEYWORDS: Cell death, Photodynamic therapy, Leukemia, Scanning electron microscopy, Control systems, Medicine, Chromatography, Luminescence, Statistical analysis, Applied sciences

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Proceedings Article | 15 February 2006 Paper

Cell death pathways associated with PDT

David Kessel, John Reiners

Proceedings Volume 6139, 613902 (2006) https://doi.org/10.1117/12.639925

KEYWORDS: Cell death, Photodynamic therapy, Proteins, Luminescence, Tumors, Signal processing, Signal detection, Camera shutters, Medicine, Tissues

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Proceedings Article | 8 April 2005 Paper

Delineating unique cellular responses to PDT

David Kessel

Proceedings Volume 5689, (2005) https://doi.org/10.1117/12.582180

KEYWORDS: Photodynamic therapy, Calcium, Proteins, Cell death, Signal processing, Luminescence, Leukemia, Tissues, Camera shutters, Oxidation

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Proceedings Article | 14 June 2004 Paper

Effects of the bile acid UDCA on PDT efficacy in vitro and in vivo

David Kessel, Michelle Castelli, Elizabeth Sykes, Greta Garbo

Proceedings Volume 5315, (2004) https://doi.org/10.1117/12.524539

KEYWORDS: Photodynamic therapy, Tumors, Luminescence, Proteins, Polarization, Calcium, Fluorescence resonance energy transfer, In vitro testing, Cancer, Cell death

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Proceedings Article | 13 June 2003 Paper

Promotion of PDT efficacy by bile acids

Michelle Castelli, John Reiners, David Kessel

Proceedings Volume 4952, (2003) https://doi.org/10.1117/12.473615

KEYWORDS: Photodynamic therapy, Cell death, Proteins, Signal detection, Luminescence, Molecules, Medicine, Cancer, Light sources, Microscopy

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Proceedings Article | 6 June 2002 Paper

What are the targets of photodynamic therapy?

David Kessel, Michelle Castelli, John Reiners

Proceedings Volume 4612, (2002) https://doi.org/10.1117/12.469340

KEYWORDS: Cell death, Photodynamic therapy, Proteins, Microchannel plates, Luminescence, Cancer, Plasma, Tissues, Microscopy, Photosensitizer targeting

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Proceedings Article | 9 April 2001 Paper

Mechanism of PDT-induced mitochondrial photodamage

David Kessel, Michelle Castelli, John Reiners

Proceedings Volume 4248, (2001) https://doi.org/10.1117/12.424448

KEYWORDS: Photodynamic therapy, Cell death, Proteins, Luminescence, Tissues, Photosensitizer targeting, Signal detection, Signal attenuation, Cancer, Oxygen

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Proceedings Article | 29 March 2000 Paper

Motexafin lutetium in graft coronary artery disease

Kathryn Woodburn, Shari Rodriquez, Atsushi Yamaguchi, Motoya Hayase, Robert Robbins, David Kessel

Proceedings Volume 3909, (2000) https://doi.org/10.1117/12.379878

KEYWORDS: Heart, Arteries, Transplantation, Lutetium, Photodynamic therapy, Tissues, Plasma, Luminescence, Angiography, Veins

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Proceedings Article | 29 March 2000 Paper

Determinants of PDT-induced apoptosis

David Kessel, Yu Luo, Hyeong-Reh Kim

Proceedings Volume 3909, (2000) https://doi.org/10.1117/12.379884

KEYWORDS: Photodynamic therapy, Cell death, Plasma, Luminescence, Leukemia, Photosensitizer targeting, Signal detection, Microchannel plates, In vitro testing, Animal model studies

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Proceedings Article | 6 July 1999 Paper

Transport, localization, and phototoxicity of m-THPC

David Kessel, Elizabeth Sykes

Proceedings Volume 3592, (1999) https://doi.org/10.1117/12.351504

KEYWORDS: Luminescence, Plasma, Bioalcohols, Proteins, Photodynamic therapy, Leukemia, In vitro testing, Adaptive optics, Tissues, Biological research

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Proceedings Article | 19 May 1998 Paper

Role of mitochondrial photodamage in PDT-induced apoptosis

Yu Luo, Zhuoyan Zhang, David Kessel

Proceedings Volume 3247, (1998) https://doi.org/10.1117/12.308138

KEYWORDS: Photodynamic therapy, Cell death, Proteins, Plasma, Luminescence, Leukemia, Magnesium, Rhodamine, Tin, Charge-coupled devices

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Proceedings Article | 22 May 1997 Paper

Photoeradication and imaging of atheromatous plaque with texaphyrins

Kathryn Woodburn, Fan Qing, David Kessel, Stuart Young

Proceedings Volume 2970, (1997) https://doi.org/10.1117/12.275065

KEYWORDS: Luminescence, Lutetium, Photodynamic therapy, Tissue optics, Tissues, Heart, Receptors, Cell death, Tumors, Blood

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Proceedings Article | 8 May 1997 Paper

Modes of cytotoxicity associated with photodynamic therapy

David Kessel, Yu Luo, Chi Chang, Barbara Henderson, Kathryn Woodburn

Proceedings Volume 2972, (1997) https://doi.org/10.1117/12.273494

KEYWORDS: Photodynamic therapy, Cell death, Microchannel plates, Tumors, In vivo imaging, Luminescence, Adaptive optics, Linear filtering, Cancer, Leukemia

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Proceedings Article | 17 May 1996 Paper

Selective uptake of texaphyrins in atheromatous plaque

Kathryn Woodburn, Stuart Young, Q. Fan, David Kessel, Richard Miller

Proceedings Volume 2671, (1996) https://doi.org/10.1117/12.239994

KEYWORDS: Lutetium, Luminescence, Plasma, Gadolinium, Magnetic resonance imaging, Proteins, Dielectrics, Photodynamic therapy, Pollution control, Heart

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Proceedings Article | 2 April 1996 Paper

Modulation of PDT-induced apoptosis by protein kinases and phosphatases

Yu Luo, Chi Chang, David Kessel

Proceedings Volume 2675, (1996) https://doi.org/10.1117/12.237530

KEYWORDS: Cell death, Photodynamic therapy, Proteins, Microchannel plates, Modulation, Leukemia, Particles, Luminescence, Tumors, Optical filters

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Proceedings Article | 1 May 1995 Paper

Mechanisms of phototoxicity catalyzed by two porphycenes

David Kessel, Yu Luo, Kathryn Woodburn, Chi Chang, Barbara Henderson

Proceedings Volume 2392, (1995) https://doi.org/10.1117/12.208180

KEYWORDS: Cell death, Luminescence, Absorbance, Tumors, Toxicity, Photodynamic therapy, Zinc, Oxygen, Plasma, Control systems

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Proceedings Article | 1 March 1995 Paper

Photodynamic therapy with cationic photosensitizers

David Kessel, Kathryn Woodburn, Chi Chang, Barbara Henderson

Proceedings Volume 2371, (1995) https://doi.org/10.1117/12.203370

KEYWORDS: Photodynamic therapy, Microchannel plates, Rhodamine, Resistance

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Proceedings Article | 19 July 1994 Paper

Photosensitization with benzochlorin iminium salts

David Kessel, Kathryn Woodburn

Proceedings Volume 2133, (1994) https://doi.org/10.1117/12.179969

KEYWORDS: Luminescence, Zinc, Analog electronics, Absorbance, Nickel, Copper, Tumors, Oxygen, Microscopy, Signal processing

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SPIE Press Book | 1 July 1993

Selected Papers on Photodynamic Therapy

Proceedings Article | 18 June 1993 Paper

Treatment parameters affecting the response of normal brain to photodynamic therapy

Qun Chen, Michael Chopp, Mary Dereski, Brian Wilson, Michael Patterson, David Kessel, Larry Heads, Fred Hetzel

Proceedings Volume 1881, (1993) https://doi.org/10.1117/12.146304

KEYWORDS: Brain, Photodynamic therapy, Tumors, Tissue optics, Optical testing, Tumor growth modeling, Biological research, Tissues, Signal attenuation, Therapeutics

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Proceedings Article | 18 June 1993 Paper

Characterization of photodynamic and sonodynamic cytotoxicity by fluorescent probes

David Kessel

Proceedings Volume 1881, (1993) https://doi.org/10.1117/12.146319

KEYWORDS: Luminescence, Ultrasonography, Analog electronics, Microscopy, Tumor growth modeling, Data modeling, Rhodamine, Signal processing, Filtering (signal processing), Photodynamic therapy

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Proceedings Article | 1 June 1992 Paper

Promotion of porphyrin cytotoxicity by ultrasound (Invited Paper)

David Kessel, Russell Jeffers, Charles Cain

Proceedings Volume 1645, (1992) https://doi.org/10.1117/12.60930

KEYWORDS: Ultrasonography, Luminescence, Tumor growth modeling, Interfaces, Leukemia, Tumors, Analog electronics, Tissues, Transducers, Photodynamic therapy

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Proceedings Article | 1 June 1991 Paper

Pharmacokinetics of Photofrin II distribution in man

David Kessel, Unyime Nseyo, Veronique Schulz, Elizabeth Sykes

Proceedings Volume 1426, (1991) https://doi.org/10.1117/12.44057

KEYWORDS: Plasma, Luminescence, Tumors, Absorbance, Tissues, Proteins, Statistical analysis, Fluorescence spectroscopy, Signal processing, Photodynamic therapy

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Proceedings Article | 21 January 1990 Paper

Photodynamic therapy: priorities for 1990

David Kessel

Proceedings Volume 10306, 1030604 (1990) https://doi.org/10.1117/12.2283666

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Showing 5 of 48 publications

Proceedings Volume Editor (23)

SPIE Conference Volume | 2 April 2024

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXII

SPIE Conference Volume | 21 April 2023

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXI

SPIE Conference Volume | 31 March 2022

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic and Photobiomodulation Therapy XXX

SPIE Conference Volume | 22 April 2021

Mechanisms and Techniques in Photodynamic Therapy and Photobiomodulation

SPIE Conference Volume | 4 March 2020

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIX

Showing 5 of 23 publications

Conference Committee Involvement (26)

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXIII

25 January 2025 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXII

27 January 2024 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXI

28 January 2023 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic and Photobiomodulation Therapy XXX

22 January 2022 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXX

6 March 2021 | Online Only, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIX

1 February 2020 | San Francisco, California, United States

17th International Photodynamic Association World Congress

28 June 2019 | Cambridge, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXVIII

2 February 2019 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXVII

27 January 2018 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXVI

28 January 2017 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXV

13 February 2016 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIV

7 February 2015 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIII

1 February 2014 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXII

3 February 2013 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXI

21 January 2012 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XX

22 January 2011 | San Francisco, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIX

23 January 2010 | San Francisco, California, United States

PDT: Back to the Future

11 June 2009 | Seattle, Washington, United States

12th World Congress of the International Photodynamic Association

11 June 2009 | Seattle, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XVIII

24 January 2009 | San Jose, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XVII

19 January 2008 | San Jose, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XVI

20 January 2007 | San Jose, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XV

21 January 2006 | San Jose, California, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy

22 January 2005 | San Jose, CA, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy

24 January 2004 | San Jose, CA, United States

Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XII

25 January 2003 | San Jose, CA, United States

Showing 5 of 26 Conference Committees

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