In this paper we demonstrate applicability of intensity-based optical coherence tomography technique for noninvasive
visualization of 3D retinal microcapillary network. The study was performed with ultra high resolution and high speed
(180,000 Ascans/sec) spectral optical coherence tomography (SOCT). New scanning protocols and data processing
algorithms have been introduced to visualize microcapillary network. Moreover, results obtained in the eyes of healthy
volunteers and patients with eye diseases were compared with fluorescein angiography.
Presented report shows that SOCT is well suited for visualization of 3D retinal capillary network in the healthy and
pathologic eyes as well. Obtained results demonstrate high correspondence with fluorescein angiography, without using
any contrast agents. Our data suggest that intensity-based SOCT has potential in the early diagnosis of the retinal