Dr. Mostafa Sadoqi Profile

Dr. Mostafa Sadoqi

Professor at St John's Univ

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Publications (9)

Proceedings Article | 9 September 2019 Presentation + Paper

Advances in Raman-based broadband optical refrigeration

Reid Vorbach, Russell Lochrie, Kenneth Sobablo, Mostafa Sadoqi, C. Fortmann

Proceedings Volume 11120, 1112003 (2019) https://doi.org/10.1117/12.2528818

KEYWORDS: Raman spectroscopy, Absorption, Phonons, Diamond, Raman scattering, Light scattering, Light wave propagation, Mirrors, Geometrical optics, Atmospheric propagation

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Proceedings Article | 14 September 2018 Presentation + Paper

Diffusive light scattering and collection for advanced device applications

Claire Alvine, Rachel Tyo, Zacarias Imperial, Kimberly Rosal, Mostafa Sadoqi, C. Fortmann

Proceedings Volume 10758, 107580E (2018) https://doi.org/10.1117/12.2320578

KEYWORDS: Absorption, Particles, Light scattering, Molecules, Solar energy, Solar cells, Refractive index, Fusion energy, Minerals, Excitons

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Proceedings Article | 14 September 2018 Presentation + Paper

Prospects for broadband spectrum Raman optical refrigeration

Rachel Tyo, Claire Alvine, Zacarias Imperial, Kimberly Rosal, Reid Vorbach, Mostafa Sadoqi, C. Fortmann

Proceedings Volume 10758, 107580J (2018) https://doi.org/10.1117/12.2322570

KEYWORDS: Raman spectroscopy, Raman scattering, Phonons, Diamond, Absorption, Light scattering, Particles, Mirrors, Scattering, Crystals

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Proceedings Article | 16 February 2012 Paper

Targeted polymeric magnetic nanoparticles for brain imaging

Bharat Kirthivasan, Dhirender Singh, Sangram Raut, Murali Mohan Bommana, Emilio Squillante, Mostafa Sadoqi

Proceedings Volume 8233, 82330T (2012) https://doi.org/10.1117/12.914655

KEYWORDS: Magnetism, Nanoparticles, Brain, Polymers, Particles, Luminescence, Blood brain barrier, Imaging systems, Neuroimaging, Brain imaging

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The purpose of this study was to develop targeted polymeric magnetic nanoparticle system for brain imaging. Near infrared dye indocyanine green (ICG) or p-gycoprotein substrate rhodamine 123 (Rh123) were encapsulated along with oleic acid coated magnetic nanoparticles (OAMNP) in a matrix of poly(lactide-co-glycolide) (PLGA) and methoxy poly(ethyleneglycol)-poly(lactide) (Met-PEG-PLA). The nanoparticles were evaluated for morphology, particle size, dye content and magnetite content. The in vivo biodistribution study was carried out using three groups of six male Sprague Dawley rats each. Group I received a saline solution containing the dye, group II received dye-loaded polymeric magnetic nanoparticles without the aid of a magnetic field, and group III received dye-loaded polymeric magnetic nanoparticles with a magnet (8000 G) placed on the head of the rat. After a preset exposure period, the animals were sacrificed and dye concentration was measured in the brain, liver, kidney, lungs and spleen homogenates. Brain sections were fixed, cryotomed and visualized using fluorescence microscopy. The particles were observed to be spherical and had a mean size of 220 nm. The encapsulation efficiency for OAMNP was 57%, while that for ICG was 56% and for Rh123 was 45%. In the biodistribution study, while the majority of the dose for all animals was found in the liver, kidneys and spleen, group III showed a significantly higher brain concentration than the other two groups (p < 0.001). This result was corroborated by the fluorescence microscopy studies, which showed enhanced dye penetration into the brain tissue for group III. Further studies need to be done to elucidate the exact mechanism responsible for the increased brain uptake of dye to help us understand if the magnetic nanoparticles actually penetrate the blood brain barrier or merely deliver a massive load of dye just outside it, thereby triggering passive diffusion into the brain parenchyma. These results reinforce the potential use of polymeric magnetically-targeted nanoparticles in active brain targeting and imaging.

Proceedings Article | 13 July 2004 Paper

Long-circulating near-infrared fluorescent nanoparticles for diagnosis and photodynamic therapy of cutaneous cancers

Vishal Saxena, Mostafa Sadoqi, S. Kumar, Jun Shao

Proceedings Volume 5312, (2004) https://doi.org/10.1117/12.534336

KEYWORDS: Nanoparticles, Cancer, Tumors, Photodynamic therapy, Luminescence, Indocyanine green, Diffusion, Molecules, Cell death, Pharmacy

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Proceedings Article | 14 June 2004 Paper

Novel near-infrared nanoparticlulate biomarker: preparation and stability studies

Vishal Saxena, Mostafa Sadoqi, Sunil Kumar, Jun Shao

Proceedings Volume 5329, (2004) https://doi.org/10.1117/12.534317

KEYWORDS: Nanoparticles, Luminescence, Tumors, Indocyanine green, Polymers, Molecules, Diffusion, Pharmacy, Diagnostics, Tissues

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Proceedings Article | 1 June 2004 Paper

Novel multifunctional near-infrared fluorescent nanoparticles: integrating nanotechnology and biophotonics

Vishal Saxena, Mostafa Sadoqi, S. Kumar, Jun Shao

Proceedings Volume 5331, (2004) https://doi.org/10.1117/12.534329

KEYWORDS: Nanoparticles, Luminescence, Tumors, Biomedical optics, Nanotechnology, Indocyanine green, Polymers, Spherical lenses, Tissue optics, Diagnostics

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Proceedings Article | 29 July 2003 Paper

Spatial sensitivity profiles by time-resolved fluorescence Monte Carlo simulation

Praveen Kadimcherla, Mostafa Sadoqi, Sunil Kumar

Proceedings Volume 4955, (2003) https://doi.org/10.1117/12.478179

KEYWORDS: Photons, Sensors, Scattering, Monte Carlo methods, Tissue optics, Absorption, Luminescence, Picosecond phenomena, Optical properties, Time resolved spectroscopy

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Proceedings Article | 29 July 2003 Paper

Optical properties by time-resolved fluorescence Monte Carlo simulation

Praveen Kadimcherla, Mostafa Sadoqi, Sunil Kumar

Proceedings Volume 4955, (2003) https://doi.org/10.1117/12.478178

KEYWORDS: Photons, Monte Carlo methods, Luminescence, Scattering, Absorption, Diffusion, Optical properties, Sensors, Time resolved spectroscopy, Tissues

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Showing 5 of 9 publications

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