Dr. Fabrice Manns Profile

Dr. Fabrice Manns

Professor at Univ of Miami

SPIE Involvement:

Conference Chair | Editor | Author

Publications (64)

Proceedings Article | 13 March 2019

Spherical aberration of the crystalline lens measured in-vitro using an LRT-OCT system (Conference Presentation)

Siobhan Williams, Marco Ruggeri, Bianca Heilman, Yu-Cherng Chang, Ashik Mohamed, Geetha Sravani, Cornelis Rowaan, Alex Gonzalez, Arthur Ho, Jean-Marie Parel, Fabrice Manns

Proc. SPIE. 10858, Ophthalmic Technologies XXIX

KEYWORDS: Monochromatic aberrations, Biometrics, Tissues, Optical coherence tomography, Crystals, Software development, Raster graphics, Geometrical optics, In vitro testing, 3D image processing

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Proceedings Article | 14 March 2018

Objective dynamic changes in lens curvature during accommodation using optical coherence tomography images (Conference Presentation)

Siobhan Williams, Giovanni Gregori, Marco Ruggeri, Yu-Cherng Chang, Florence Cabot, Arthur Ho, Sonia Yoo, Jean-Marie Parel, Fabrice Manns

Proc. SPIE. 10474, Ophthalmic Technologies XXVIII

KEYWORDS: Optical spheres, Detection and tracking algorithms, Visualization, Calibration, Optical coherence tomography, Image analysis, In vivo imaging

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Proceedings Article | 16 May 2017

Combined laser-ray tracing and OCT system for biometry of the crystalline lens (Conference Presentation)

Marco Ruggeri, Bianca Maceo Heilman, Yue Yao, Yu-Cherng Chang, Alex Gonzalez, Cornelis Rowaan, Ashik Mohamed, Siobhan Williams, Heather Durkee, Juan Silgado, Andres Bernal, Esdras Arrieta-Quintero, Arthur Ho, Jean-Marie Parel, Fabrice Manns

Proc. SPIE. 10045, Ophthalmic Technologies XXVII

KEYWORDS: Refractive index, Eye, Imaging systems, Optical coherence tomography, Crystals, Laser development, Holmium, Laser crystals, Refractor telescopes, Biophysics

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Proceedings Article | 16 May 2017

Synchronous imaging of the pulse response of the ciliary muscle and lens with SD-OCT (Conference Presentation)

Yu-Cherng Chang, Alex Pham, Siobhan Williams, Karam Alawa, Carolina de Freitas, Marco Ruggeri, Jean-Marie Parel, Fabrice Manns

Proc. SPIE. 10045, Ophthalmic Technologies XXVII

KEYWORDS: Eye, Biometrics, Cornea, Imaging systems, Optical coherence tomography, Image segmentation, Distortion, Optical testing, Refraction, Biophysics

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Proceedings Article | 26 April 2016

Simultaneous hand-held contact color fundus and SD-OCT imaging for pediatric retinal diseases (Conference Presentation)

Marco Ruggeri, Victor Hernandez, Carolina De Freitas, Nidhi Relhan, Juan Silgado, Fabrice Manns, Jean-Marie Parel

Proc. SPIE. 9693, Ophthalmic Technologies XXVI

KEYWORDS: Eye, Imaging systems, Cameras, Optical coherence tomography, Retina, Photography, Diagnostics, Digital cameras, Retinal scanning, Ophthalmoscopy

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Proceedings Article | 26 April 2016

Simultaneous refraction measurement and OCT axial biometry of the eye during accommodation (Conference Presentation)

Carolina De Freitas, Victor Hernandez, Marco Ruggeri, Heather Durkee, Siobhan Williams, Giovanni Gregori, Arthur Ho, Fabrice Manns, Jean-Marie Parel

Proc. SPIE. 9693, Ophthalmic Technologies XXVI

KEYWORDS: Eye, Biometrics, Optical spheres, Optical coherence tomography, Wavefront sensors, Data acquisition, Refraction, Holmium, Optical alignment, Optical switching

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Proceedings Article | 12 March 2015

Co-focused ultrasound and optical coherence elastography system for the study of age-related changes of biomechanical properties of crystalline lens in rabbit eyes

Chen Wu, Zhaolong Han, Shang Wang, Jiasong Li, Manmohan Singh, Chih-hao Liu, Salavat Aglyamov, Stanislav Emelianov, Fabrice Manns, Kirill Larin

Proc. SPIE. 9307, Ophthalmic Technologies XXV

KEYWORDS: Eye, Coherence (optics), Tissues, Ultrasonography, Optical coherence tomography, Crystals, Transducers, Elastography, Acoustics, Crystallography

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Proceedings Article | 12 March 2015

Determining the optomechanical properties of accommodating gel for lens refilling surgery using finite element analysis and numerical ray-tracing

Hooman Mohammad-Pour, Sangarapillai Kanapathipillai, Fabrice Manns, Arthur Ho

Proc. SPIE. 9307, Ophthalmic Technologies XXV

KEYWORDS: Refractive index, Data modeling, Mechanics, Surgery, Crystals, Ions, Amplifiers, Finite element methods, Geometrical optics, Protactinium

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Proceedings Article | 4 March 2014

Combining optical coherence tomography with acoustic radiation force for depth-dependent biomechanics of crystalline lens

Shang Wang, Salavat Aglyamov, Andrei Karpiouk, Jiasong Li, Stanislav Emelianov, Fabrice Manns, Kirill Larin

Proc. SPIE. 8934, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII

KEYWORDS: Eye, Biomedical optics, Tissues, Ultrasonography, Optical coherence tomography, Crystals, Tissue optics, Elastography, Acoustics, Natural surfaces

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Proceedings Article | 28 February 2014

Biometry of the ciliary muscle during dynamic accommodation assessed with OCT

Marco Ruggeri, Victor Hernandez, Carolina de Freitas, Fabrice Manns, Jean-Marie Parel

Proc. SPIE. 8930, Ophthalmic Technologies XXIV

KEYWORDS: Refractive index, Eye, Imaging systems, Optical coherence tomography, Image segmentation, Image processing, Sclera, Ray tracing, Algorithm development, 3D image processing

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Proceedings Article | 28 February 2014

Finite element study on the effects of GRIN order on the accommodative response of the human crystalline lens

Hooman Mohammad-Pour, Sangarapillai Kanapathipillai, Fabrice Manns, Arthur Ho

Proc. SPIE. 8930, Ophthalmic Technologies XXIV

KEYWORDS: GRIN lenses, Optical components, Refractive index, Eye, Data modeling, Crystals, Computing systems, Numerical analysis, Geometrical optics, Crystallography

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Proceedings Article | 3 March 2010

Small animal ocular biometry using optical coherence tomography

Marco Ruggeri, Omer Kocaoglu, Stephen Uhlhorn, David Borja, Raksha Urs, Tsung-Han Chou, Vittorio Porciatti, Jean-Marie Parel, Fabrice Manns

Proc. SPIE. 7550, Ophthalmic Technologies XX

KEYWORDS: Refractive index, Eye, Biometrics, Cornea, Optical coherence tomography, Image segmentation, Interfaces, Refraction, Ray tracing, In vivo imaging

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Proceedings Article | 18 April 2005

Noncontact optical measurement of lens capsule thickness during simulated accommodation

Noel Ziebarth, Fabrice Manns, Carolina Acosta, Jean-Marie Parel

Proc. SPIE. 5688, Ophthalmic Technologies XV

KEYWORDS: Actuators, Refractive index, Optical design, Eye, Tissues, Optical testing, Aspheric lenses, Fiber couplers, Tissue optics, Natural surfaces

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Purpose: To non-invasively measure the thickness of the anterior and posterior lens capsule, and to determine if it significantly changes during accommodation. Methods: Anterior and posterior capsule thickness was measured on post-mortem lenses using a non-contact optical system using a focus-detection technique. The optical system uses a 670nm laser beam delivered to a single-mode fiber coupler. The output of the fiber coupler is focused on the tissue surface using an aspheric lens (NA=0.68) mounted on a translation stage with a motorized actuator. Light reflected from the sample surface is collected by the fiber coupler and sent to a photoreceiver connected to a computer-controlled data acquisition system. Optical intensity peaks are detected when the aspheric lens is focused on the capsule boundaries. The capsule thickness is equal to the distance traveled between two peaks multiplied by the capsule refractive index. Anterior and posterior lens capsule thickness measurements were performed on 18 cynomolgus (age average: 6±1 years, range: 4-7 years) eyes, 1 rhesus (age: 2 years) eye, and 12 human (age average: 65±16, range: 47-92) eyes during simulated accommodation. The mounted sample was placed under the focusing objective of the optical system so that the light was incident on the center pole. Measurements were taken of the anterior lens capsule in the unstretched and the stretched 5mm states. The lens was flipped, and the same procedure was performed for the posterior lens capsule. Results: The precision of the optical system was determined to be ±0.5um. The resolution is 4um and the sensitivity is 52dB. The human anterior lens capsule thickness was 6.0±1.2um unstretched and 4.9±0.9um stretched (p=0.008). The human posterior lens capsule was 5.7±1.2um unstretched and 5.7±1.4um stretched (p=0.974). The monkey anterior lens capsule thickness was 5.9±1.9um unstretched and 4.8±1.0um stretched (p=0.002). The monkey posterior lens capsule was 5.9±2.0um unstretched and 5.1±1.3um stretched (p=0.128). Conclusions: The results indicate that the primate anterior lens capsule thickness changes during accommodation.

Proceedings Article | 18 April 2005

Ex-vivo crystalline lens optical quality measurements during simulated accommodation using a single pass PSF measurement system

David Borja, Gaku Takeuchi, Katsuhiko Kobayashi, Fabrice Manns, Jean Marie Parel

Proc. SPIE. 5688, Ophthalmic Technologies XV

KEYWORDS: Optical transfer functions, Point spread functions, Spatial frequencies, Crystals, Sclera, Quality measurement, Optical testing, Relays, Modulation transfer functions, Crystal optics

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Proceedings Article | 13 July 2004

Noncontact optical measurement of lens capsule thickness ex vivo

Noel Ziebarth, Fabrice Manns, Stephen Uhlhorn, Jean-Marie Parel

Proc. SPIE. 5314, Ophthalmic Technologies XIV

KEYWORDS: Refractive index, Optical design, Eye, Tissues, Optical testing, Objectives, Aspheric lenses, Fiber couplers, Signal detection, Power meters

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Proceedings Article | 13 July 2004

Modelling the performance of accommodating intraocular lenses

Arthur Ho, Fabrice Manns, Therese Pham, Simon Evans, Jean-Marie Parel

Proc. SPIE. 5314, Ophthalmic Technologies XIV

KEYWORDS: Optical components, Modeling, Eye, Cornea, Retina, Crystals, Vitreous, Intraocular lenses, Performance modeling, Eye models

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Proceedings Article | 13 July 2004

Kinetics of corneal thermal shrinkage

David Borja, Fabrice Manns, William Lee, Jean-Marie Parel

Proc. SPIE. 5314, Ophthalmic Technologies XIV

KEYWORDS: Eye, Statistical analysis, Cornea, Data modeling, Tissues, Sensors, Collagen, Thermal modeling, Temperature metrology, Data analysis

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Proceedings Article | 13 July 2004

Effect of the internal optics on the outcome of custom-LASIK in an eye model

Fabrice Manns, Arthur Ho, Jean-Marie Parel

Proc. SPIE. 5314, Ophthalmic Technologies XIV

KEYWORDS: Monochromatic aberrations, Eye, Biomedical optics, Cornea, Surgery, Wavefronts, Wavefront aberrations, 3D modeling, Eye models, OSLO

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Proceedings Article | 12 September 2003

Predictions of tissue denaturation during experimental laser interstitial thermotherapy for breast tumors

Nelson Salas, Fabrice Manns, Jean-Marie Parel, Peter Milne, David Denham, David Robinson

Proc. SPIE. 4949, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII

KEYWORDS: Breast, Tumors, Tissues, Fiber lasers, Tissue optics, Molybdenum, Laser tissue interaction, Temperature metrology, Laser systems engineering, Heat therapy

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Proceedings Article | 12 September 2003

Microsurgical laser Doppler probe for simultaneous intraoperative monitoring of cochlear blood flow and electrocochleography from the round window

Lidet Abiy, Fred Telischi, Jean-Marie Parel, Fabrice Manns, Ralph Saettele, Krzysztof Morawski, Ozcan Ozdamar, John Borgos, Rafael Delgado, Edward Miskiel, Erdem Yavuz

Proc. SPIE. 4949, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII

KEYWORDS: Doppler effect, Nerve, Surgery, Electrodes, Blood circulation, Ear, In vivo imaging, Intelligence systems, Laser beam diagnostics, Prototyping

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Proceedings Article | 14 July 2003

Corneal ablation rate at 266 nm

Per Soderberg, Fabrice Manns, Stephen Sulhorn, Nelson Salas, Peggy Lamar, Jean-Marie Parel

Proc. SPIE. 4951, Ophthalmic Technologies XIII

KEYWORDS: Microscopes, Eye, Clocks, Cornea, Tissues, Calibration, Solid state lasers, Scanning electron microscopy, Laser ablation, Vitreous

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Proceedings Article | 14 July 2003

Assessing changes in physical lens dimensions during immersion in tissue preservation media using shadowphotogrammetry

Alexander Rosen, David Denham, Fabrice Manns, Viviana Fernandez, Joseph Stoiber, Robert Augusteyn, Jean-Marie Parel

Proc. SPIE. 4951, Ophthalmic Technologies XIII

KEYWORDS: Eye, Digital photography, Visualization, Tissues, Crystals, Control systems, Digital imaging, Profiling, Vitreous, Liquids

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Proceedings Article | 14 July 2003

Qualitative optical-thermal model of argon, selective, and microsecond infrared laser trabeculoplasty

Fabrice Manns, Jean-Marie Parel, Viviana Fernandez, Joseph Stoiber, Peggy Lamar, Nelson Salas, Francisco Fantes

Proc. SPIE. 4951, Ophthalmic Technologies XIII

KEYWORDS: Continuous wave operation, Diffusion, Argon ion lasers, Nd:YAG lasers, Laser scattering, Infrared lasers, Tissue optics, Laser optics, Thermal modeling, Absorption

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Proceedings Article | 14 July 2003

Laser-induced photochemical surface modification of PMMA for fibrin-free intraocular lens

Yuji Sato, Katsuya Tanizawa, Fabrice Manns, Jean-Marie Parel, Masataka Murahara

Proc. SPIE. 4951, Ophthalmic Technologies XIII

KEYWORDS: Proteins, Polymethylmethacrylate, Tissues, Lamps, Transmittance, Excimer lasers, Excimers, Fluorine, Natural surfaces, Absorption

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Proceedings Article | 14 July 2003

Effects of immersion solutions on corneal tissue strip hydration and thermal shrinkage

David Borja, Fabrice Manns, Peggy Lamar, Alexander Rosen, Jean-Marie Parel

Proc. SPIE. 4951, Ophthalmic Technologies XIII

KEYWORDS: Eye, Cornea, Tissues, Ultrasonography, Photography, Thermal effects, Process control, Tissue optics, Laser tissue interaction, Temperature metrology

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SPIE Journal Paper | 1 April 2003

Semianalytical thermal model for subablative laser heating of homogeneous nonperfused biological tissue: application to laser thermokeratoplasty

Fabrice Manns, David Borja, Jean-Marie Parel, William Smiddy, William Culbertson

JBO Vol. 8 Issue 02

KEYWORDS: Tissues, Convection, Cornea, Laser tissue interaction, Thermal modeling, Pulsed laser operation, Absorption, Collimation, Laser irradiation, Scattering

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Proceedings Article | 17 June 2002

Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 940 nm

Nelson Salas, Fabrice Manns, Jean-Marie Parel, Peter Milne, Manuel Figueroa, David Denham, David Robinson

Proc. SPIE. 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII

KEYWORDS: Laser therapeutics, Laser vision correction, Surgery, Calcium, Laser tissue interaction, Heat therapy

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Proceedings Article | 13 June 2002

Anterior ciliary sclerotomy: effect on corneal topography, globe integrity, and the role of a novel antifibrotic gel

Peggy Lamar, Viviana Fernandez, Fabrice Manns, Sander Dubovy, Stanley Zipper, Samith Sandadi, Natsushi Nakagawa, Marc Weiser, Francois Malecaze, Jean-Marie Parel

Proc. SPIE. 4611, Ophthalmic Technologies XII

KEYWORDS: Eye, Diamond, Quantum wells, Safety, Surgery, Sclera, Holmium, Sodium, Vitreous, Earth Viewing Camera

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Proceedings Article | 13 June 2002

Thermoelectrically controlled device for studies of temperature-induced corneal shrinkage

David Borja, Fabrice Manns, Viviana Fernandez, Peggy Lamar, Per Soederberg, Jean-Marie Parel

Proc. SPIE. 4611, Ophthalmic Technologies XII

KEYWORDS: Eye, Cornea, Tissues, Sensors, Calibration, Copper, Computing systems, Data acquisition, Thermoelectric materials, Temperature metrology

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Proceedings Article | 13 June 2002

Synthetic cornea: biocompatibility and optics

Jean-Marie Parel, Stefan Kaminski, Viviana Fernandez, E. Alfonso, Peggy Lamar, Emmanuel Lacombe, Bernard Duchesne, Sander Dubovy, Fabrice Manns, Pascal Rol

Proc. SPIE. 4611, Ophthalmic Technologies XII

KEYWORDS: Eye, Polymethylmethacrylate, Cornea, Tissues, Surgery, Polymers, Excimer lasers, Tissue optics, Natural surfaces, Animal model studies

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Purpose. Experimentally find a method to provide a safe surgical technique and an inexpensive and long lasting mesoplant for the restoration of vision in patients with bilateral corneal blindness due to ocular surface and stromal diseases. Methods. Identify the least invasive and the safest surgical technique for synthetic cornea implantation. Identify the most compatible biomaterials and the optimal shape a synthetic cornea must have to last a long time when implanted in vivo. Results. Penetrating procedures were deemed too invasive, time consuming, difficult and prone to long term complications. Therefore a non-penetrating delamination technique with central trephination was developed to preserve the integrity of Descemet's membrane and the anterior segment. Even though this approach limits the number of indications, it is acceptable since the majority of patients only have opacities in the stroma. The prosthesis was designed to fit in the removed tissue plane with its skirt fitted under the delaminated stroma. To improve retention, the trephination wall was made conical with the smallest opening on the anterior surface and a hat-shaped mesoplant was made to fit. The skirt was perforated in its perimeter to allow passage of nutrients and tissues ingrowths. To simplify the fabrication procedure, the haptic and optic were made of the same polymer. The intrastromal biocompatibility of several hydrogels was found superior to current clinically used PMMA and PTFE materials. Monobloc mesoplants made of 4 different materials were implanted in rabbits and followed weekly until extrusion occurred. Some remained optically clear allowing for fundus photography. Conclusions. Hydrogel synthetic corneas can be made to survive for periods longer than 1 year. ArF excimer laser photoablation studies are needed to determine the refractive correction potential of these mesoplants. A pilot FDA clinical trial is needed to assess the mesoplant efficacy and very long-term stability.

Proceedings Article | 13 June 2002

Calculation of corneal temperature and shrikage during laser thermokeratoplasty (LTK)

Fabrice Manns, David Borja, Jean-Marie Parel

Proc. SPIE. 4611, Ophthalmic Technologies XII

KEYWORDS: Thermography, Laser vision correction, Cornea, Data modeling, Tissues, Collagen, Laser irradiation, Pulsed laser operation, Thermal modeling, Laser tissue interaction

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Proceedings Article | 7 June 2001

Feasibility of simultaneous correction of ametropia by varying gel refractive index with phaco-ersatz

Arthur Ho, Paul Erickson, Fabrice Manns, Therese Pham, Jean-Marie Parel

Proc. SPIE. 4245, Ophthalmic Technologies XI

KEYWORDS: Refractive index, Eye, Cornea, Polymers, Crystals, Ray tracing, Aspheric lenses, Spherical lenses, Eye models, Photorefractive polymers

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Proceedings Article | 7 June 2001

Measurement of the topography of human cadaver lenses using the PAR corneal topography system

Viviana Fernandez, Fabrice Manns, Stanley Zipper, Samith Sandadi, Marie Hamaoui, Hassan Tahi, Arthur Ho, Jean-Marie Parel

Proc. SPIE. 4245, Ophthalmic Technologies XI

KEYWORDS: Microscopes, Eye, Ophthalmology, Cornea, Lenses, Polymers, Crystals, Medical research, Natural surfaces, Eye models

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Proceedings Article | 7 June 2001

Corneal modeling using conic section fits of PAR corneal topography system measurements

Stanley Zipper, Fabrice Manns, Viviana Fernandez, Samith Sandadi, Arthur Ho, Jean-Marie Parel

Proc. SPIE. 4245, Ophthalmic Technologies XI

KEYWORDS: Microscopes, Monochromatic aberrations, MATLAB, Eye, Optical spheres, Cornea, Medical research, Shape analysis, Eye models, Systems modeling

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Proceedings Article | 7 June 2001

Calculation of the primary spherical aberration of an eye model using paraxial ray tracing with matrix optics

Fabrice Manns, Arthur Ho, Jean-Marie Parel

Proc. SPIE. 4245, Ophthalmic Technologies XI

KEYWORDS: Monochromatic aberrations, Eye, Laser vision correction, Cornea, Surgery, Refraction, LASIK, Optical matrix switches, Spherical lenses, Eye models

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Proceedings Article | 21 May 2001

X-ray monitoring of laser interstitial thermotherapy (LITT) in ex-vivo porcine tissue

Ahmed Minhaj, Fabrice Manns, Peter Milne, David Denham, Nelson Salas, Jean-Marie Parel, David Robinson

Proc. SPIE. 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI

KEYWORDS: Optical fibers, Tissues, Imaging systems, X-rays, Laser irradiation, X-ray lasers, X-ray imaging, Laser tissue interaction, Temperature metrology, Heat therapy

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Proceedings Article | 21 May 2001

Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 980 nm and 830 nm

Nelson Salas, Fabrice Manns, Jean-Marie Parel, Peter Milne, Ahmed Minhaj, David Denham, David Robinson

Proc. SPIE. 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI

KEYWORDS: Breast, Optical fibers, Tumors, Tissues, Semiconductor lasers, Tissue optics, Laser tissue interaction, Temperature metrology, Laser systems engineering, Heat therapy

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Proceedings Article | 7 June 2000

Ex-vivo testing of crystalline lens substitutes: a pilot study

Marie Hamaoui, Jean-Marie Parel, Fabrice Manns, Hassan Tahi, Arthur Ho, Brien Holden

Proc. SPIE. 3908, Ophthalmic Technologies X

KEYWORDS: Microscopes, Eye, Cornea, Surgery, Polymers, Crystals, Photography, In vivo imaging, Vitreous, Eye models

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Proceedings Article | 7 June 2000

Assessment of changes in corneal shape as a function of intraocular pressure: a pilot study

Kira Brenman, Hassan Tahi, Fabrice Manns, Bernard Duchesne, Jean-Marie Parel, Emmanuel Lacombe

Proc. SPIE. 3908, Ophthalmic Technologies X

KEYWORDS: Eye, Statistical analysis, Cornea, Tissues, Sensors, Transplantation, Vitreous, Natural surfaces, Refractor telescopes, Biophysics

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Proceedings Article | 7 June 2000

Intraocular implants for the surgical correction of presbyopia

Jean-Marie Parel, Pascal Rol, Hassan Tahi, Fabrice Manns, Peter Milne, Marie Hamaoui, Arthur Ho, Brien Holden

Proc. SPIE. 3908, Ophthalmic Technologies X

KEYWORDS: Monochromatic aberrations, Eye, Cornea, Visualization, Tissues, Surgery, Polymers, Crystals, Intraocular lenses, Clinical trials

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Proceedings Article | 17 May 2000

Development of a tissue phantom for experimental studies on laser interstitial thermotherapy of breast cancer

Nelson Salas, Fabrice Manns, Pascal Chapon, Peter Milne, Sergio Mendoza, David Denham, Jean-Marie Parel, David Robinson

Proc. SPIE. 3907, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X

KEYWORDS: Breast, Breast cancer, Tumors, Tissues, Laser irradiation, Tissue optics, Laser tissue interaction, Temperature metrology, Absorption, Heat therapy

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Proceedings Article | 22 June 1999

In-situ measurement and analysis of the temperature fields in laser interstitial thermotherapy of breast cancer

Peter Milne, Fabrice Manns, David Denham, Jean-Marie Parel, David Robinson

Proc. SPIE. 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX

KEYWORDS: Breast, Laser therapeutics, Breast cancer, Fiber optics, Tissues, Fiber lasers, In vivo imaging, Tissue optics, Temperature metrology, Heat therapy

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Proceedings Article | 22 June 1999

Mathematical analysis of the temperature field during ex-vivo and in-vivo experimental laser interstitial thermotherapy (LITT) in breast tissue models

Fabrice Manns, Peter Milne, Nelson Salas, Nish Pandya, David Denham, Jean-Marie Parel, David Robinson

Proc. SPIE. 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX

KEYWORDS: Continuous wave operation, Breast cancer, Tissues, Semiconductor lasers, Laser irradiation, In vivo imaging, Laser beam diagnostics, Laser tissue interaction, Temperature metrology, Heat therapy

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Proceedings Article | 22 June 1999

Developing clinical trials for breast cancer interstitial therapy

David Robinson, Jean-Marie Parel, Peter Milne, Fabrice Manns, David Denham

Proc. SPIE. 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX

KEYWORDS: Breast, Oncology, Laser therapeutics, Cancer, Breast cancer, Tumors, Tissues, Ultrasonography, Mammography, Clinical trials

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Proceedings Article | 18 June 1999

Scanning photorefractive keratectomy at 213 nm: PMMA ablations

Fabrice Manns, Pascal Rol, Martin Wosnitza, Patrick Maine, Jean-Marie Parel

Proc. SPIE. 3591, Ophthalmic Technologies IX

KEYWORDS: Polymethylmethacrylate, Cornea, Nd:YAG lasers, Optical testing, Laser ablation, Near field, Beam shaping, Laser beam diagnostics, Pulsed laser operation, Near field optics

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Proceedings Article | 18 June 1999

Analysis of eye models for the development of observation contact lenses

Pascal Rol, Fabrice Manns, Jean-Marie Parel, Franz Fankhauser, Peter Niederer

Proc. SPIE. 3591, Ophthalmic Technologies IX

KEYWORDS: Monochromatic aberrations, Refractive index, Mirrors, Eye, Cornea, Data modeling, Glasses, Contact lenses, Eye models, Cones

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Proceedings Article | 1 June 1998

Scleral indentation height after laser scleral buckling

Se Kang, Jean-Marie Parel, Fabrice Manns, Jawheung Lee, William Smiddy

Proc. SPIE. 3246, Ophthalmic Technologies VIII

KEYWORDS: Eye, Medicine, Ophthalmology, Laser vision correction, Laser energy, Silicon, Sclera, Laser beam diagnostics, Pulsed laser operation, Direct methods

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Proceedings Article | 1 June 1998

Corneal group refractive index measurement using low-coherence interferometry

Stephen Uhlhorn, Fabrice Manns, Hassan Tahi, Pascal Rol, Jean-Marie Parel

Proc. SPIE. 3246, Ophthalmic Technologies VIII

KEYWORDS: Refractive index, Mirrors, Eye, Cornea, Reflection, Interferometers, Interferometry, Optical testing, Geometrical optics, In vitro testing

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Proceedings Article | 1 June 1998

Spot diameters for scanning photorefractive keratectomy: a comparative study

Fabrice Manns, Jean-Marie Parel

Proc. SPIE. 3246, Ophthalmic Technologies VIII

KEYWORDS: Monochromatic aberrations, Eye, Laser therapeutics, Laser vision correction, Cornea, Surgery, Computer simulations, Laser ablation, Algorithm development, Refractor telescopes

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Proceedings Article | 26 May 1997

Scleral heating with pulsed midinfrared lasers and temperature-dependent absorption coefficient

Fabrice Manns, Jean-Marie Parel

Proc. SPIE. 2971, Ophthalmic Technologies VII

KEYWORDS: Mid-IR, Tissues, Diffusion, Sclera, Pulsed laser operation, Eye models, Thermal modeling, Laser tissue interaction, Temperature metrology, Absorption

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Proceedings Article | 26 May 1997

Optical comparison of multizone and single-zone photorefractive keratectomy

Xochitl Gonzalez-Cirre, Fabrice Manns, Pascal Rol, Jean-Marie Parel

Proc. SPIE. 2971, Ophthalmic Technologies VII

KEYWORDS: Point spread functions, Eye, Computer aided diagnosis and therapy, Cornea, Tissues, Retina, Electroluminescence, Image quality, Computer aided design, Eye models

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Proceedings Article | 22 May 1997

Update of laser hyperthermic treatment for primary breast cancer: ex-vivo and in-vivo models

David Robinson, Jean-Marie Parel, Xochitl Gonzalez-Cirre, David Denham, Fabrice Manns, Peter Milne, Robert Schachner, Alan Herron, Jason Comander, Gerhard Hauptmann

Proc. SPIE. 2970, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII

KEYWORDS: Laser therapeutics, Tumor growth modeling, Breast cancer, Tissues, Distortion, Instrument modeling, Clinical trials, Animal model studies

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