The Imaging X-ray Polarimetry Explorer (IXPE) will expand the information space for study of cosmic sources, by adding polarization to the properties (time, energy, and position) observed in x-ray astronomy. Selected in 2017 January as a NASA Astrophysics Small Explorer (SMEX) mission, IXPE will be launched into an equatorial orbit in 2021. The IXPE observatory includes three identical x-ray telescopes, each comprising a 4-m-focal-length (grazing-incidence) mirror module assembly (MMA) and a polarization-sensitive (imaging) detector unit (DU). The optical bench separating the MMAs from the DUs is a deployable boom with a tip/tilt/rotation stage for DU-to-MMA (gang) alignment, similar to the configuration used for the NuSTAR observatory. The IXPE mission will provide scientifically meaningful measurements of the x-ray polarization of a few dozen sources in the 2-8 keV band, over the first two years of the mission. For several bright, extended x-ray sources (pulsar wind nebulae, supernova remnants, and an active-galaxy jet), IXPE observations will produce polarization maps indicating the magnetic structure of the synchrotron emitting regions. For many bright pulsating x-ray sources (isolated pulsars, accreting x-ray pulsars, and magnetars), IXPE observations will produce phase-resolved profiles of the polarization degree and position angle.
IXPE scientific payload comprises of three telescopes, each composed of a mirror and a photoelectric polarimeter based on the Gas Pixel Detector design. The three focal plane detectors, together with the unit which interfaces them to the spacecraft, are named IXPE Instrument and they will be built and calibrated in Italy; in this proceeding, we will present how IXPE Instrument will be calibrated, both on-ground and in-flight. The Instrument Calibration Equipment is being finalized at INAF-IAPS in Rome (Italy) to produce both polarized and unpolarized radiation, with a precise knowledge of direction, position, energy and polarization state of the incident beam. In flight, a set of four calibration sources based on radioactive material and mounted on a filter and calibration wheel will allow for the periodic calibration of all of the three IXPE focal plane detectors independently. A highly polarized source and an unpolarized one will be used to monitor the response to polarization; the remaining two will be used to calibrate the gain through the entire lifetime of the mission.