Prof. Frank V. Bright Profile

Prof. Frank V. Bright

Assistant Professor at Univ at Buffalo

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Publications (7)

Proceedings Article | 1 February 2012 Paper

Xerogel-nanocrystallite hybrids for optical sensing

Frank Bright, Ian Horner, Caley Caras, Nadine Kraut, Randi Deuro, Justin Reynard

Proceedings Volume 8212, 82120N (2012) https://doi.org/10.1117/12.905144

KEYWORDS: Silicon, Sensors, Sol-gels, Luminescence, Nanoparticles, Chemistry, Polymers, Quantum dots, Silica, Semiconductor lasers

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Proceedings Article | 16 February 2009 Paper

Enabling intelligent readout of luminescent signals from nanoscale biochemical sensors

Lei Yao, Frank Bright, Ka Yi Yung, Vamsy Chodavarapu, Vijay Tripathi, Alexander Cartwright

Proceedings Volume 7188, 71880E (2009) https://doi.org/10.1117/12.816026

KEYWORDS: Sensors, Luminescence, CMOS sensors, Signal processing, Oxygen, Imaging systems, Signal detection, Digital electronics, Intelligent sensors, Phototransistors

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The development of intelligent miniaturized biochemical sensors has been an area of active research over the past several years. These microsensors and sensor microarrays are finding niche applications in point-of-care diagnostics, personal care, food safety, and environmental monitoring. Among these sensors, optical (luminescence) sensing holds a great promise towards implementing simple, specific, and highly sensitive biochemical sensors. It is generally understood that biochemical recognition elements that respond specifically to the target analytes play a critical role in the overall sensor operation. Aside from the recognition elements, signal detection and processing components are important to collect the information provided by recognition elements and output an easily understandable response. The signal processing component provides the best opportunity to incorporate intelligence to achieve low-power, adaptive, accurate, and reliable sensors. We deal with sensors that use sol-gel derived xerogels as recognition materials and Complementary Metal-Oxide Semiconductor (CMOS) integrated circuits for signal detection and processing. Xerogels are nano/microporous glasses that can be used to encapsulate luminophores, enzymes, and nanoparticles in their pores. In this Article, we will describe some of the emerging integrated sensor platforms that are based on monitoring the excited-state luminescence intensity and lifetimes of the luminophores housed in the xerogels. Specifically, we describe a CMOS imaging system for simultaneously monitoring xerogels sensor arrays. Next, we describe a non-linear phase luminometric system with enhanced and dynamically tunable sensitivity and improved signal-to-noise performance. Finally, we will describe time-based signal processing that could enable the direct measurement of excited state fluorescence lifetimes. This time-to-digital converter requires simple circuit implementation and can be used to measure lifetimes that are on the order of several hundred nanoseconds. The time based signal processing could ultimately allow the development of low-cost lifetime imaging system wherein one could take the lifetimes' image of an array of recognition elements rather than collecting an image of their fluorescence intensities.

Proceedings Article | 12 February 2007 Paper

Nanostructured porous polymeric photonic bandgap structures for sensing

Mark Swihart, Rachel Bukowski, Sung Jin Kim, Alexander Cartwright, Vamsy Chodavarapu, Timothy Bunning, A. Titus, Frank Bright

Proceedings Volume 6447, 64470O (2007) https://doi.org/10.1117/12.716666

KEYWORDS: Sensors, Polymers, Chemical elements, Oxygen, Luminescence, Polymeric sensors, Structural sensing, Reflection, Glucose, Optical sensors

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Proceedings Article | 28 February 2006 Paper

CMOS-based biosensor systems using integrated nanostructured recognition elements

Daniil Shubin, Frank Bright, Vamsy Chodavarapu, Elizabeth Tehan, Rachel Bukowski, Albert Titus, Alexander Cartwright

Proceedings Volume 6095, 60950O (2006) https://doi.org/10.1117/12.649907

KEYWORDS: Sensors, CMOS sensors, Glucose, Luminescence, Light emitting diodes, Microsystems, Nanostructuring, Signal detection, Phase shifts, Phase measurement

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Proceedings Article | 12 October 2005 Paper

Biomolecule-less sensors for biomolecules based on templated xerogel platforms

Ying Tang, Frank Bright, Albert Titus, Rachel Bukowski, Alexander Cartwright, William Holthoff, Elizabeth Tehan, Ellen Shughart, Zunyu Tao

Proceedings Volume 5969, 59690F (2005) https://doi.org/10.1117/12.629169

KEYWORDS: Proteins, Sensors, Chemical elements, Polymers, Biological research, Plasma, Molecules, Chemical analysis, Biosensors, Luminescence

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Proceedings Article | 23 November 1999 Paper

Issues involved in using sol-gel-derived glasses as platforms for chemical sensing

Frank Bright, Siddharth Pandey, Gary Baker, Meagan Doody, Neil Bonzagni

Proceedings Volume 3856, (1999) https://doi.org/10.1117/12.371293

KEYWORDS: Luminescence, Biological research, Glasses, Chemical elements, Statistical analysis, Biosensors, Fluorescence anisotropy, Polymers, Time multiplexed optical shutter, Biological and chemical sensing

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Proceedings Article | 30 April 1993 Paper

Characterization of a sol-gel-entrapped artificial receptor

Upvan Narang, Richard Dunbar, Frank Bright, Paras Prasad

Proceedings Volume 1796, (1993) https://doi.org/10.1117/12.143523

KEYWORDS: Sensors, Fiber optics sensors, Sol-gels, Chemical elements, Fiber optics, Receptors, Glasses, Fiber optic components, Chemical analysis, Luminescence

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Showing 5 of 7 publications

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