Dr. Fu-Ping Xu Profile

Dr. Fu-Ping Xu

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Proceedings Article | 17 May 2019 Paper

Evaluation of free radical scavenging and anti-oxidative capacity of vespae nidus-epimedii folium formula

Fu-ping Xu, Zi-cong Wu, Tong-sheng Chen, Yi-fei Wang, Zhi-ping Wang

Proceedings Volume 11170, 111700E (2019) https://doi.org/10.1117/12.2531797

KEYWORDS: Absorbance, Medicine, Iron, Life sciences, Oxygen, Laser applications, Arthritis, Skin, Magnesium, Cancer

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Vespae nidus has been used in traditional Chinese medicine for thousands of years to treat a variety of diseases, including malignant tumors, rheumatoid arthritis, lung diseases, skin disease, digestive and urinary disorders, and dental diseases. As the same, Epimedii folium used to treat kidney-Yang deficiency,impotence and seminal emission, limp wilting sinews and bones, rheumatic arthralgia, Numbness and paralysis, osteoporosis. Vespae nidus-Epimedii folium formula used to treat chronic arthralgia due to Yang deficiency, and painful joints. But the underlying mechanisms by which it exerts therapeutic function have not been thoroughly studied. Cellular damage induced by free-radicals like reactive oxygen species has been implicated in several diseases. Hence naturally anti-oxidant play a vital role in combating these conditions. In this study, The effects of Vespae Nidus nidus-Epimedii folium formula aqueous extract (VEF) on free radical scavenging and anti-oxidative capacity is investigated. By free radical scavenging assays, the IC50 value of VEF were 71.33, 54.07 μg/mL with DPPH, ABTS assay respectively, and 0.161mg ferrous sulfate/1 mg VEF with FRAP assay. These results indicated that the antioxidant properties of VEF hold great potential used as an alternative to more toxic synthetic anti-oxidants as an additive in food, cosmetic and pharmaceutical preparations for the oxidative diseases treatment.

Proceedings Article | 17 May 2019 Paper

Evaluation of free radical scavenging and anti-oxidative capacity of Guigan longmu Decoction

Fu-ping Xu, Zi-cong Wu, Tong-sheng Chen, Yi-fei Wang, Zhi-ping Wang

Proceedings Volume 11170, 111700D (2019) https://doi.org/10.1117/12.2531791

KEYWORDS: Absorbance, Medicine, Iron, Life sciences, Oxygen, Magnesium, Bioalcohols, Calibration, Laser applications, Heart

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Guigan longmu Decoction(GL), take in Zhong-jing Zhang’s Treatise on Exogenous of Febrile Diseases, composed of Cinnamomum cassia Presl(Guizhi), Glycyrrhiza uralensis Fisch.(Gancao), Fossil fragments(Longgu) and Oyster shell(Muli), is a traditional Chinese medicine(TCM) formula and is widely used as a clinically medication formula for its efficiency in improving sleep. But the underlying mechanisms by which it exerts therapeutic function have not been thoroughly studied. Cellular damage induced by free-radicals like reactive oxygen species has been implicated in several diseases. Hence naturally anti-oxidant play a vital role in combating these conditions. In this study, The effects of GL on free radical scavenging and anti-oxidative capacity is investigated. By free radical scavenging assays, the IC₅₀ values of GL were 46.03±1.26, 51.45±0.74 μg/ml with DPPH, ABTS assay respectively, and 0.611 mg ferrous sulfate/1 mg GL with FRAP assay. These results indicated that the antioxidant properties of GL hold great potential used as an alternative to more toxic synthetic anti-oxidants as an additive in food, cosmetic and pharmaceutical preparations for the oxidative diseases treatment.

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