Dr. Gaurav Rawal Profile

Dr. Gaurav Rawal

at Iowa State Univ of Science and Technology

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 13 March 2024 Poster + Paper

3D-printed nanoplasmonic device with super-hydrophobic sample concentrator for biosensing

Qinming Zhang, Gaurav Rawal, Jingjing Qian, Jianqiang Zhang, Liang Dong, Meng Lu

Proceedings Volume 12861, 128610D (2024) https://doi.org/10.1117/12.3000427

KEYWORDS: Sensors, Biological samples, Biosensors, Viruses, Fabrication, 3D printing, Biological research, Nanoplasmonics

Read Abstract +

This work reports a 3D-printed virus sensing device that combines the functions of sample enrichment and quantification. The device consists of a nanoplasmonic biosensor surrounded by a biomimetic superhydrophobic structure. The superhydrophobic structure serves as a sample concentrator that can enrich the target analyte, which is subsequentially quantified by the nanoplasmonic biosensor. Both nanoscale sensor and microscale hydrophobic sample concentrator were fabricated using a high-resolution 3D printer through two-photon polymerization lithography (TPL). The design of the 3D-printed superhydrophobic microstructure was inspired by natural patterns found on surfaces like lotus leaves, which are known for their water-repellent properties. The TPP-based 3D printing approach enables the integration of two functions into one chip with a low-cost, high resolution, and simple fabrication process. This system was used to detect the swine influenza A virus contained in sample droplet with a starting volume of 25 μL. During a test, the droplet volume reduced due to evaporation, which was facilitated by the plasmonic heating. As a results the droplet’s diameter can shrink from 3.5 mm to 0.1 mm within 15 minutes. The volume reduction corresponds to the virus concentration increase over 4 × 10⁴ times. The implementation of superhydrophobic sample concentration around of the sensor significantly improved the immobilization of target viruses on the plasmonic sensor. The device not only achieved a higher sensitivity but also reduced the assay time.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years