Dr. Gracie Vargas Profile

Dr. Gracie Vargas

Professor at Univ of Texas Medical Branch

SPIE Involvement:

Senior status | Conference Program Committee | Conference Co-Chair | Author

Publications (24)

PROCEEDINGS ARTICLE | May 3, 2016

Combining large area fluorescence with multiphoton microscopy for improved detection of oral epithelial neoplasia (Conference Presentation)

Proc. SPIE. 9701, Multimodal Biomedical Imaging XI

KEYWORDS: Target detection, Glucose, Multiphoton microscopy, Microscopy, Luminescence, 3D modeling, Harmonic generation, Analog electronics, Connective tissue, Multiphoton fluorescence microscopy

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PROCEEDINGS ARTICLE | April 27, 2016

Volumetric imaging of oral epithelial neoplasia by MPM-SHGM: epithelial connective tissue interface (Conference Presentation)

Proc. SPIE. 9712, Multiphoton Microscopy in the Biomedical Sciences XVI

KEYWORDS: Second-harmonic generation, Multiphoton microscopy, Tumor growth modeling, Cancer, Microscopy, Interfaces, Diagnostics, 3D modeling, Image analysis, Connective tissue

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SPIE Journal Paper | April 15, 2013

Optical coherence tomography for assessment of microbicide safety in a small animal model

Bell, Brent , Vincent, Kathleen , Bourne, Nigel , Vargas, Gracie , Motamedi, Massoud

JBO Vol. 18 Issue 04

KEYWORDS: Optical coherence tomography, Tissues, Animal model studies, In vivo imaging, Safety, Imaging systems, Tissue optics, Photomicroscopy, Toxicity, Visualization

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PROCEEDINGS ARTICLE | March 22, 2013

Combination of widefield fluorescence imaging and nonlinear optical microscopy of oral epithelial neoplasia

Proc. SPIE. 8572, Advanced Biomedical and Clinical Diagnostic Systems XI

KEYWORDS: Optical imaging, Multiphoton microscopy, Atrial fibrillation, Cancer, Tumors, Tissues, Microscopy, Luminescence, Biopsy, Harmonic generation

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PROCEEDINGS ARTICLE | February 22, 2013

Nonlinear optical microscopy and microspectroscopy of oral precancers and early cancer

Proc. SPIE. 8588, Multiphoton Microscopy in the Biomedical Sciences XIII

KEYWORDS: Multiphoton microscopy, Tumor growth modeling, Cancer, Spectroscopy, Microscopy, Luminescence, Optical microscopy, Imaging spectroscopy, Multiphoton spectroscopy, Animal model studies

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SPIE Journal Paper | November 1, 2012

Automated segmentation algorithm for detection of changes in vaginal epithelial morphology using optical coherence tomography

Chitchian, Shahab , Vincent, Kathleen , Vargas, Gracie , Motamedi, Massoud

JBO Vol. 17 Issue 11

KEYWORDS: Image segmentation, Optical coherence tomography, Tissues, Algorithm development, Image filtering, Detection and tracking algorithms, Toxicity, Image processing algorithms and systems, Natural surfaces, Biopsy

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PROCEEDINGS ARTICLE | February 9, 2012

NF-kB activation as a biomarker of light injury using a transgenic mouse model

Proc. SPIE. 8221, Optical Interactions with Tissue and Cells XXIII

KEYWORDS: Confocal microscopy, Injuries, Retina, Laser induced damage, Microscopy, Luminescence, In vivo imaging, Neuroimaging, Mouse models, Brain

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PROCEEDINGS ARTICLE | February 28, 2011

Two-photon autofluorescence spectroscopy of oral mucosa tissue

Proc. SPIE. 7903, Multiphoton Microscopy in the Biomedical Sciences XI

KEYWORDS: Mirrors, Second-harmonic generation, Cancer, Tissues, Spectroscopy, Imaging spectroscopy, Biopsy, Tissue optics, Signal detection, Multiphoton spectroscopy

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PROCEEDINGS ARTICLE | February 17, 2010

Feasibility of using gold nanorods for optical contrast in two photon microscopy of oral carcinogenesis

Proc. SPIE. 7576, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II

KEYWORDS: Gold, Confocal microscopy, Tumor growth modeling, Cancer, Tissues, Luminescence, In vivo imaging, Two photon excitation microscopy, Signal detection, Nanorods

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SPIE Journal Paper | March 1, 2008

Use of hyperosmotic chemical agent to improve the laser treatment of cutaneous vascular lesions

Vargas, Gracie , Barton, Jennifer , Welch, Ashley

JBO Vol. 13 Issue 02

KEYWORDS: Skin, Blood vessels, Laser coagulation, Tissue optics, Doppler effect, Laser irradiation, Tissues, Blood circulation, Laser therapeutics, Signal attenuation

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PROCEEDINGS ARTICLE | March 23, 2007

Quantitative intracellular calcium sensing with two-photon fluorescence lifetime imaging microscopy

Proc. SPIE. 6424, Photonic Therapeutics and Diagnostics III

KEYWORDS: Tissues, Calibration, Microscopy, Luminescence, Calcium, Signal processing, Fluorescence lifetime imaging, Neuroimaging, Neurons, Brain

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PROCEEDINGS ARTICLE | February 10, 2007

In vivo mucosal tissue imaging using fiber-based two-photon approach

Proc. SPIE. 6442, Multiphoton Microscopy in the Biomedical Sciences VII

KEYWORDS: Two photon imaging, Photonic crystal fibers, Multiphoton microscopy, Tissues, Microscopy, Luminescence, Photonic crystals, Single mode fibers, Collagen, In vivo imaging

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PROCEEDINGS ARTICLE | February 22, 2006

In vivo multiphoton and second harmonic generation microscopy of epithelial carcinogenesis

Proc. SPIE. 6091, Optical Biopsy VI

KEYWORDS: Second-harmonic generation, Multiphoton microscopy, Tumor growth modeling, Tissues, Microscopy, Collagen, Biopsy, In vivo imaging, Harmonic generation, Photomicroscopy

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PROCEEDINGS ARTICLE | July 1, 2004

Creating the invisible man

Proc. SPIE. 5319, Laser Interaction with Tissue and Cells XV

KEYWORDS: Refractive index, Tissues, Blood vessels, Skin, Light scattering, Collimation, Blood circulation, In vivo imaging, Tissue optics, In vitro testing

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SPIE Journal Paper | March 1, 2004

Use of optical coherence tomography to monitor biological tissue freezing during cryosurgery

Choi, Bernard , Milner, Thomas , Kim, Jeehyun , Goodman, Jared , Vargas, Gracie , Aguilar, Guillermo , Nelson, John

JBO Vol. 9 Issue 02

KEYWORDS: Optical coherence tomography, Skin, Liquids, Tissue optics, Nitrogen, Water, In vivo imaging, Reflectivity, Tissues, Scattering

PROCEEDINGS ARTICLE | August 1, 2003

In vivo results using photothermal tomography for imaging cutaneous blood vessels

Proc. SPIE. 5047, Smart Nondestructive Evaluation and Health Monitoring of Structural and Biological Systems II

KEYWORDS: Infrared cameras, Infrared imaging, Laser therapeutics, Blood vessels, Skin, Laser irradiation, Tomography, Infrared radiation, In vivo imaging, Absorption

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PROCEEDINGS ARTICLE | June 17, 2002

Dynamic measurements of laser light attenuation by cryogen film and frost formation

Proc. SPIE. 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII

KEYWORDS: Sensors, Signal attenuation, Glasses, Skin, Light scattering, Optical testing, Transmittance, Pulsed laser operation, Cryogenics, Liquids

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PROCEEDINGS ARTICLE | July 9, 2001

Thermally induced birefringence changes in cartilage using polarization-sensitive optical coherence tomography

Proc. SPIE. 4257, Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical

KEYWORDS: Infrared imaging, Cartilage, Polarization, Birefringence, Optical coherence tomography, Nd:YAG lasers, Collagen, Laser irradiation, Radiometry, Thermodynamics

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PROCEEDINGS ARTICLE | June 13, 2000

In-vitro Erbium:YAG laser lithotripsy

Proc. SPIE. 3914, Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical

KEYWORDS: Laser therapeutics, Laser energy, Fiber lasers, Calculus, Sapphire, Laser lithotripsy, Er:YAG lasers, Acoustics, Pulsed laser operation, Plasma

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PROCEEDINGS ARTICLE | May 17, 2000

Use of osmotically active agents to alter optical properties of tissue: influence on the detected fluorescence signal from a subsurface target

Proc. SPIE. 3907, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X

KEYWORDS: Optical properties, Tissues, Scattering, Skin, Luminescence, Fluorescence spectroscopy, In vivo imaging, Tissue optics, Signal detection, In vitro testing

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PROCEEDINGS ARTICLE | May 17, 2000

Selective photocoagulation of cutaneous blood vessels: evaluation of vessel damage by color Doppler optical coherence tomography

Proc. SPIE. 3907, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X

KEYWORDS: Doppler effect, Visualization, Imaging systems, Blood, Blood vessels, Optical coherence tomography, Video, Skin, Blood circulation, Doppler tomography

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PROCEEDINGS ARTICLE | April 28, 2000

Influence of optical absorption on urinary calculus threshold fluence and ablation efficiency during infrared laser ablation

Proc. SPIE. 3925, Biomedical Applications of Free-Electron Lasers

KEYWORDS: Laser ablation, Calculus, Infrared radiation, Absorbance, Laser damage threshold, Tissue optics, Free electron lasers, Calculi, Hard tissue optics, Absorption

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PROCEEDINGS ARTICLE | June 22, 1999

Mechanisms of laser-induced thermal coagulation of whole blood in vitro

Proc. SPIE. 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX

KEYWORDS: Scattering, Cameras, Blood, Optical coherence tomography, Skin, Laser scattering, Laser damage threshold, Pulsed laser operation, In vitro testing, Temperature metrology

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PROCEEDINGS ARTICLE | April 30, 1999

Assessing vessel damage with color Doppler optical coherence tomography following irradiations with cooling

Proc. SPIE. 3598, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III

KEYWORDS: Ferroelectric materials, Blood vessels, Optical coherence tomography, Skin, Laser irradiation, Blood circulation, Pulsed laser operation, Doppler tomography, Cryogenics, Temperature metrology

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