The high-resolution remote sensing camera has higher requirements on the optical axis stability. However, during the in-orbit operation, the main structure of the remote sensing camera and the attitude drift of the satellite will cause the optical axis to be unstable and cause the image quality declines. In this paper, an optical image stabilization system based on fast steering mirror is designed on the basis of a large-aperture high-resolution gaze-type remote sensing camera. The system divides the sub-field of view at the edge of the field of the remote sensing camera, installs the high frame rate and high sensitivity to the camera in the field of view, and then uses the related characteristic of the acquired image to measure the image and obtain the jitter information of the optical axis. Finally, the system will feedback the information to the control system to drive the fast steering mirror, in order to achieve the optical axis of the jitter compensation to ensure the optical axis stability.For the typical ground scene image, the system can improve the control precision and bandwidth by optimizing the image shift measurement algorithm and improving the calculation speed. In summary, the image stabilization system with high precision, high bandwidth and high success rate.