In recent years, many applications have been recognized for biomedical imaging techniques utilizing terahertz frequency
radiation. This is largely due to the capability of unique tissue identification resulting from the nature of the interaction
between THz radiation and the molecular structure of the cells. By THz identification methods, tissue changes in tooth
enamel, cartilage, and malignant cancer cells have already been demonstrated. Terahertz Time-Domain Spectroscopy
(THz-TDS) remains one of the most versatile methods for spectroscopic image acquisition for its ability to
simultaneously determine amplitude and phase over a broad spectral range.
In this study we investigate the use of THz imaging techniques to uniquely identify damage types in tissue samples for
both forensic and treatment applications. Using THz-TDS imaging in both transmission and reflection schemes, we
examine tissue samples which have been damaged using a variety of acids. Each method of damage causes structural
deterioration to the tissue by a different mechanism, thus leaving the remaining tissue uniquely changed based on the
damage type. We correlate the change in frequency spectra, phase shift for each damage type to the mechanisms and
severity of injury.