Dynamic contrast enhanced (DCE) MRI is the method of choice for clinical tumor detection. There are three categories
of DCE-MRI analysis methods including qualitative DCE-MRI, semi-quantitative DCE-MRI, and quantitative
DCE-MRI. Among these three categories, quantitative DCE-MRI is the only one that could provide pharmacokinetic
parameters and directly reveal physiological state of tumor. In this paper, we have made a brief review on quantitative
DCE-MRI. Firstly, physiological basis of DCE-MRI was described in details. Then, two kinds of contrast agent, low
molecular weighted contrast media (LMCM) and macromolecular contrast media (MMCM), are introduced respectively.
After that, several T1 weighted DCE-MRI data analysis methods are introduced, too. At last, possible further
developments of DCE-MRI have been discussed.