Prof. Hui Gong Profile

Prof. Hui Gong

Co-founder/Scientist at Britton Chance Ctr for Biomedical Photonics

SPIE Involvement:

Conference Chair | Author

Publications (64)

PROCEEDINGS ARTICLE | March 14, 2018

Cryo-micro-optical sectioning tomography for label-free brainwide visualization of senile plaque (Conference Presentation)

Proc. SPIE. 10481, Neural Imaging and Sensing 2018

KEYWORDS: Visualization, Luminescence, Tomography, Visual optics, Alzheimer's disease, Brain mapping

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PROCEEDINGS ARTICLE | March 14, 2018

Advanced NeuroGPS-Tree achieves brain-wide reconstruction of neuronal population equal to manual reconstruction level (Conference Presentation)

Proc. SPIE. 10481, Neural Imaging and Sensing 2018

KEYWORDS: Image resolution, 3D modeling, Neuroscience, Reconstruction algorithms, Neuroimaging, 3D visualizations, Neurons, Brain imaging, Brain

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PROCEEDINGS ARTICLE | April 19, 2017

High-throughput dual-color precision imaging for brain-wide mapping of the connectome with cytoarchitectonic landmarks at the cellular level (Conference Presentation)

Proc. SPIE. 10051, Neural Imaging and Sensing

KEYWORDS: Lithium, Tissues, Image processing, Image resolution, Tomography, Neuroimaging, 3D image processing, Brain mapping, Neurons, Brain

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PROCEEDINGS ARTICLE | April 19, 2017

ReagentTF: a rapid and versatile optical clearing method for biological imaging (Conference Presentation)

Proc. SPIE. 10051, Neural Imaging and Sensing

KEYWORDS: Lithium, Visualization, Tissues, Luminescence, Optical clearing, Fluorescent proteins, Current controlled current source, Brain

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PROCEEDINGS ARTICLE | April 26, 2016

Fast whole-brain optical tomography capable of automated slice-collection (Conference Presentation)

Proc. SPIE. 9690, Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation

KEYWORDS: Proteins, Tissues, Imaging systems, Composites, Optical microscopy, Optical tomography, Neuroimaging, Tissue optics, Brain mapping, Brain

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SPIE Journal Paper | March 11, 2016

Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol

Tingting Yu, Yisong Qi, Jianru Wang, Wei Feng, Jianyi Xu, Jingtan Zhu, Yingtao Yao, Hui Gong, Qingming Luo, Dan Zhu

JBO Vol. 21 Issue 08

KEYWORDS: Brain, Luminescence, Optical clearing, Neuroimaging, Tissues, Green fluorescent protein, Tissue optics, Optical imaging, Neurons, Collagen

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PROCEEDINGS ARTICLE | March 10, 2015

Optimized optical clearing method for imaging central nervous system

Proc. SPIE. 9305, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics II

KEYWORDS: Transparency, Green fluorescent protein, Tissues, Imaging systems, Luminescence, Photoacoustic tomography, Optical clearing, Nervous system, Neuroimaging, Brain

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SPIE Conference Volume | October 3, 2014

Twelfth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2014)

SPIE Journal Paper | September 25, 2014

Fast and automatic imaging of immunoenzyme-stained neuronal circuits in the whole brain of Drosophila

Qingping Tian, Jing Yuan, Yuxin Li, Tao Jiang, Hui Gong, Wei Zhou

JBO Vol. 19 Issue 09

KEYWORDS: Brain, Neuroimaging, Imaging systems, Neurons, Image resolution, Confocal microscopy, 3D image processing, Tomography, Genetics, Lithium

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PROCEEDINGS ARTICLE | September 17, 2014

Automatic detection and quantitative analysis of cells in the mouse primary motor cortex

Proc. SPIE. 9230, Twelfth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2014)

KEYWORDS: Image compression, Image segmentation, Image processing, Quantitative analysis, Gaussian filters, Image filtering, Neuroimaging, Binary data, 3D image processing, Brain

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SPIE Journal Paper | May 26, 2014

Studying hemispheric lateralization during a Stroop task through near-infrared spectroscopy-based connectivity

Lei Zhang, Jinyan Sun, Bailei Sun, Qingming Luo, Hui Gong

JBO Vol. 19 Issue 05

KEYWORDS: Near infrared spectroscopy, Brain, Hemodynamics, Neuroimaging, Spectroscopy, Brain imaging, Data conversion, Sun, Data analysis, Functional magnetic resonance imaging

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PROCEEDINGS ARTICLE | March 20, 2014

Technical considerations on confocal based fluorescence micro-optical sectioning tomography for visualizing brain circuits

Proc. SPIE. 8928, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics

KEYWORDS: Confocal microscopy, Biomedical optics, Visualization, Imaging systems, Luminescence, Image resolution, Tomography, Neuroimaging, Fluorescence tomography, Brain

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PROCEEDINGS ARTICLE | March 5, 2014

Studying hemispheric lateralization during a Stroop task by near-infrared spectroscopy

Proc. SPIE. 8928, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics

KEYWORDS: Continuous wave operation, Wavelet transforms, Sensors, Electrodes, Hemodynamics, Near infrared spectroscopy, Brain activation, Prefrontal cortex, Data conversion, Brain

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SPIE Journal Paper | September 25, 2013

Correlation between hemodynamic and electrophysiological signals dissociates neural correlates of conflict detection and resolution in a Stroop task: a simultaneous near-infrared spectroscopy and event-related potential study

Jinyan Sun, Bailei Sun, Lei Zhang, Qingming Luo, Hui Gong

JBO Vol. 18 Issue 09

KEYWORDS: Near infrared spectroscopy, Hemodynamics, Electrodes, Brain, Statistical analysis, Electroencephalography, Sensors, Signal detection, Signal processing, Prefrontal cortex

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SPIE Journal Paper | July 10, 2013

Assessing the effects of norepinephrine on single cerebral microvessels using optical-resolution photoacoustic microscope

Yanyan Liu, Xiaoquan Yang, Hui Gong, Bowen Jiang, Hui Wang, Guoqiang Xu, Yong Deng

JBO Vol. 18 Issue 07

KEYWORDS: Oxygen, Brain, Photoacoustic microscopy, Photoacoustic spectroscopy, Acoustics, Blood, Microscopes, Blood circulation, Biomedical optics, Hemodynamics

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SPIE Journal Paper | June 11, 2013

Fast optical sectioning obtained by structured illumination microscopy using a digital mirror device

Dongli Xu, Tao Jiang, Anan Li, Bihe Hu, Zhao Feng, Hui Gong, Shaoqun Zeng, Qingming Luo

JBO Vol. 18 Issue 06

KEYWORDS: Brain, Digital micromirror devices, Mirrors, Microscopy, Neuroimaging, Imaging systems, 3D image processing, Biomedical optics, Luminescence, Neuroscience

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SPIE Journal Paper | May 28, 2013

Improved detectability of neuronal connectivity on mechanical sectioning setup by using confocal detection

Xiaoli Qi, Hanqing Xiong, Xiaohua Lv, Jianling Chen, Hui Gong, Qingming Luo, Shaoqun Zeng

JBO Vol. 18 Issue 05

KEYWORDS: Confocal microscopy, Signal detection, Luminescence, Optical tomography, Tomography, Imaging systems, Neuroimaging, Brain, Image resolution, Mechanics

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PROCEEDINGS ARTICLE | December 11, 2012

Quadratic trianqular element for diffuse optical tomography

Proc. SPIE. 8553, Optics in Health Care and Biomedical Optics V

KEYWORDS: Optical components, Biomedical optics, Scattering, Matrices, Photons, Finite element methods, Tissue optics, Chemical elements, Linear elements, Diffuse optical tomography

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SPIE Journal Paper | August 8, 2012

Micro-computed tomography-guided, non-equal voxel Monte Carlo method for reconstruction of fluorescence molecular tomography

Guotao Quan, Kan Wang, Xiaoquan Yang, Yong Deng, Qingming Luo, Hui Gong

JBO Vol. 17 Issue 8

KEYWORDS: Monte Carlo methods, Luminescence, Optical properties, Glasses, Fluorescence tomography, Tomography, Tissue optics, Inverse problems, Photons, Image segmentation

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SPIE Journal Paper | July 31, 2012

In vivo imaging of hemodynamics and oxygen metabolism in acute focal cerebral ischemic rats with laser speckle imaging and functional photoacoustic microscopy

Zilin Deng, Zhen Wang, Xiaoquan Yang, Qingming Luo, Hui Gong

JBO Vol. 17 Issue 8

KEYWORDS: Ischemia, Hemodynamics, Oxygen, Arteries, Veins, Mode conditioning cables, In vivo imaging, Photoacoustic spectroscopy, Blood, Brain

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SPIE Journal Paper | May 7, 2012

Early monitoring of cerebral hypoperfusion in rats by laser speckle imaging and functional photoacoustic microscopy

Hui Wang, Xiaoquan Yang, Zhen Wang, Zilin Deng, Hui Gong, Qingming Luo

JBO Vol. 17 Issue 6

KEYWORDS: Brain, Blood vessels, Arteries, Blood, Oxygen, Veins, Cerebral cortex, Neuroimaging, Hemodynamics, Tissues

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SPIE Journal Paper | April 1, 2011

Visualization of light propagation in visible Chinese human head for functional near-infrared spectroscopy

Ting Li, Hui Gong, Qingming Luo

JBO Vol. 16 Issue 04

KEYWORDS: Head, Brain, Signal detection, Cerebral cortex, Monte Carlo methods, Tissues, Visible radiation, Visualization, Data modeling, Brain activation

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SPIE Journal Paper | February 1, 2011

Monte Carlo-based fluorescence molecular tomography reconstruction method accelerated by a cluster of graphic processing units

Guotao Quan, Hui Gong, Yong Deng, Jianwei Fu, Qingming Luo

JBO Vol. 16 Issue 02

KEYWORDS: Monte Carlo methods, Luminescence, Computing systems, Fluorescence tomography, Tomography, Finite element methods, Computer simulations, Tissue optics, Graphics processing units, Visualization

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SPIE Journal Paper | January 1, 2010

Comparisons of muscle oxygenation changes between arm and leg muscles during incremental rowing exercise with near-infrared spectroscopy

Zhongxing Zhang, Bangde Wang, Hui Gong, Guodong Xu, Shoko Nioka, Britton Chance

JBO Vol. 15 Issue 01

KEYWORDS: Near infrared spectroscopy, Oxygen, Blood, Carbon monoxide, Tissue optics, Sensors, Biomedical optics, Heart, Resistance

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SPIE Journal Paper | September 1, 2009

Hemodynamic and electrophysiological signals of conflict processing in the Chinese-character Stroop task: a simultaneous near-infrared spectroscopy and event-related potential study

Jiahuan Zhai, Ting Li, Zhongxing Zhang, Hui Gong

JBO Vol. 14 Issue 05

KEYWORDS: Near infrared spectroscopy, Hemodynamics, Signal processing, Electrodes, Performance modeling, Prefrontal cortex, Brain, Signal detection, Cognition, Biomedical optics

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PROCEEDINGS ARTICLE | February 23, 2009

Simultaneous functional near-infrared brain imaging and event-related potential studies of Stroop effect

Proc. SPIE. 7161, Photonic Therapeutics and Diagnostics V

KEYWORDS: Continuous wave operation, Electrodes, Hemodynamics, Electroencephalography, Prefrontal cortex, Electrophysiology, Functional magnetic resonance imaging, Neurovascular coupling, Brain imaging, Brain

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PROCEEDINGS ARTICLE | May 1, 2007

A novel analysis method for near infrared spectroscopy based on Hilbert-Huang transform

Proc. SPIE. 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine

KEYWORDS: Near infrared, Data modeling, Wavelets, Fourier transforms, Interference (communication), Signal processing, Prefrontal cortex, Cerebral blood flow, Signal analyzers, Brain

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PROCEEDINGS ARTICLE | May 1, 2007

Different hemodynamic response of prefontal area for men and women to mental arithmetic: a near-infrared spectroscopy study

Proc. SPIE. 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine

KEYWORDS: Statistical analysis, Sensors, Blood, Photonics, Hemodynamics, Near infrared spectroscopy, Prefrontal cortex, Neuroimaging, Functional magnetic resonance imaging, Brain

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PROCEEDINGS ARTICLE | May 1, 2007

Modulation of temperature on optical properties of rat skin in vivo

Proc. SPIE. 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine

KEYWORDS: Optical fibers, Optical properties, Scattering, Skin, Light scattering, Reflectivity, In vivo imaging, Tissue optics, Temperature metrology, Absorption

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PROCEEDINGS ARTICLE | April 26, 2007

A high-resolution optical imaging system for obtaining the serial transverse section images of biologic tissue

Proc. SPIE. 6535, Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII

KEYWORDS: Optical imaging, Microscopes, Tissues, Imaging systems, Image resolution, Objectives, Optical resolution, Charge-coupled devices, Tissue optics, Brain

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PROCEEDINGS ARTICLE | April 26, 2007

Monitor glucose induced changes in optical properties of rat skin in vitro

Proc. SPIE. 6535, Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII

KEYWORDS: Optical fibers, Glucose, Optical properties, Tissues, Scattering, Skin, Optical clearing, Tissue optics, In vitro testing, Absorption

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PROCEEDINGS ARTICLE | February 15, 2007

Elicitation interval dependent spatiotemporal evolution of cortical spreading depression waves revealed by optical intrinsic signal imaging

Proc. SPIE. 6445, Optical Diagnostics and Sensing VII

KEYWORDS: Optical imaging, Potassium, Biomedical optics, Tissues, Blood, Electrodes, Reflectivity, Image acquisition, Wave propagation, Light wave propagation

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PROCEEDINGS ARTICLE | February 13, 2007

Design and evaluation of a simultaneous fNIRS/ERP instrument

Proc. SPIE. 6434, Optical Tomography and Spectroscopy of Tissue VII

KEYWORDS: Light emitting diodes, Tissues, Sensors, Blood, Electrodes, Amplifiers, Linear filtering, Electroencephalography, Near infrared spectroscopy, Brain

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PROCEEDINGS ARTICLE | October 27, 2006

Design and evaluation of a portable continuous-wave NIR topography instrument

Proc. SPIE. 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine

KEYWORDS: Near infrared, Continuous wave operation, Light emitting diodes, Sensors, Blood, Photodiodes, Absorbance, Near infrared spectroscopy, Signal detection, Brain

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PROCEEDINGS ARTICLE | October 27, 2006

A digital rat atlas of sectional anatomy

Proc. SPIE. 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine

KEYWORDS: Iron, Tissues, Image segmentation, Image processing, Scanners, 3D modeling, Computed tomography, Eye models, 3D image processing, Brain

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PROCEEDINGS ARTICLE | July 21, 2006

The empiristic theory of photon migrating in local tissue and estimation of the optical properties from reflectance measurement

Proc. SPIE. 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII

KEYWORDS: Optical properties, Tissues, Scattering, Light scattering, Reflectivity, Optical testing, Monte Carlo methods, Tissue optics, Light, Anisotropy

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PROCEEDINGS ARTICLE | March 3, 2006

Combine temporal clustering analysis with least square estimation to determine the dynamic pattern of cortical spreading depression

Proc. SPIE. 6085, Complex Dynamics and Fluctuations in Biomedical Photonics III

KEYWORDS: Optical imaging, Biomedical optics, Statistical analysis, Blood, Reflectivity, Image analysis, Wave propagation, Binary data, Functional magnetic resonance imaging, Lead

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PROCEEDINGS ARTICLE | February 22, 2006

Study of the left prefrontal cortex activity of Chinese children with dyslexia in phonological processing by NIRS

Proc. SPIE. 6078, Photonic Therapeutics and Diagnostics II

KEYWORDS: Light emitting diodes, Tissues, Hemodynamics, Near infrared spectroscopy, Prefrontal cortex, Neuroimaging, Cerium, Positron emission tomography, Functional magnetic resonance imaging, Brain

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PROCEEDINGS ARTICLE | February 2, 2006

Generalized diffusion approximation for highly absorbing media and small source-detector separations

Proc. SPIE. 6026, ICO20: Biomedical Optics

KEYWORDS: Tissues, Scattering, Sensors, Photons, Diffusion, Light scattering, Monte Carlo methods, Collimation, Absorption, Anisotropy

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PROCEEDINGS ARTICLE | March 31, 2005

Monitoring calcium concentration in dendritic spines of cultured hippocampal neurons with cameleons

Proc. SPIE. 5703, Plasmonics in Biology and Medicine II

KEYWORDS: Confocal microscopy, Luminescence, Molecules, Diffusion, Calcium, Fluorescence resonance energy transfer, Spine, Dendrites, Neurons, Synaptic plasticity

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PROCEEDINGS ARTICLE | March 29, 2005

Verbal working memory load affects prefrontal cortices activation: evidence from a functional NIRS study in humans

Proc. SPIE. 5696, Complex Dynamics and Fluctuations in Biomedical Photonics II

KEYWORDS: Light emitting diodes, Imaging systems, Sensors, Hemodynamics, Near infrared spectroscopy, Prefrontal cortex, Neuroimaging, Positron emission tomography, Functional magnetic resonance imaging, Brain

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PROCEEDINGS ARTICLE | March 29, 2005

Enhancement of synaptic transmission induced by BDNF in cultured cortical neurons

Proc. SPIE. 5696, Complex Dynamics and Fluctuations in Biomedical Photonics II

KEYWORDS: Cadmium, Luminescence, Calcium, Photonics, Receptors, Action potentials, Sodium, Neurons, Synaptic plasticity, Synaptic transmission

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PROCEEDINGS ARTICLE | January 18, 2005

Micro-CT images reconstruction and 3D visualization for small animal studying

Proc. SPIE. 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II

KEYWORDS: Visualization, Sensors, X-rays, Computing systems, Charge-coupled devices, Ear, Reconstruction algorithms, X-ray imaging, CCD image sensors, 3D image processing

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PROCEEDINGS ARTICLE | January 18, 2005

Monitoring of prefrontal cortex activation during verbal n-back task with 24-channel functional NIRS imager

Proc. SPIE. 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II

KEYWORDS: Light emitting diodes, Biomedical optics, Cognitive modeling, Imaging systems, Hemodynamics, Near infrared spectroscopy, Prefrontal cortex, Neuroimaging, Positron emission tomography, Brain

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PROCEEDINGS ARTICLE | December 8, 2003

In vivo optical imaging of cortical spreading depression in rat