Proceedings Article | 13 March 2017
Proc. SPIE. 10137, Medical Imaging 2017: Biomedical Applications in Molecular, Structural, and Functional Imaging
KEYWORDS: Image segmentation, Image processing, X-rays, Arteries, Image registration, Medical imaging, Angiography, Computed tomography, Electronics engineering, Fluoroscopy, X-ray imaging, Motion models, Cardiac imaging
We propose a novel method for nonrigid registration of coronary arteries within frames of a fluoroscopic X-ray angiogram sequence with propagated deformation field. The aim is to remove the motion of coronary arteries in order to simplify further registration of the 3D vessel structure obtained from computed tomography angiography, with the x-ray sequence. The Proposed methodology comprises two stages: propagated adjacent pairwise nonrigid registration, and, sequence-wise fixed frame nonrigid registration. In the first stage, a propagated nonrigid transformation reduces the disparity search range for each frame sequentially. In the second stage, nonrigid registration is applied for all frames with a fixed target frame, thus generating a motion-aligned sequence. Experimental evaluation conducted on a set of 7 fluoroscopic angiograms resulted in reduced target registration error, compared to previous methods, showing the effectiveness of the proposed methodology.
