Dr. Ida Leah Gitajn Profile

Dr. Ida Leah Gitajn

at Dartmouth-Hitchcock Medical Ctr

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Author

Publications (4)

Proceedings Article | 5 March 2021 Paper

ICG-based dynamic contrast-enhanced fluorescence imaging guided open orthopaedic surgery: pilot patient study

Shudong Jiang, Jonathan Elliott, Jin Xing, Xu Cao, Xiaohan Yu, Xinyue Han, Rebecca Dabrowski, Melanie Christian, Eric Henderson, Brian Pogue, I. Leah Gitajn

Proc. SPIE. 11625, Molecular-Guided Surgery: Molecules, Devices, and Applications VII

KEYWORDS: Contamination, Tissues, Surgery, Luminescence, Indocyanine green, Bone, Blood circulation, Machine learning

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SPIE Journal Paper | 31 August 2020

Perspective on optical imaging for functional assessment in musculoskeletal extremity trauma surgery

Ida Gitajn, Gerard Slobogean, Eric Henderson, Arvind von Keudell, Mitchel Harris, John Scolaro, Nathan O'Hara, Jonathan Elliott, Brian Pogue, Shudong Jiang

JBO Vol. 25 Issue 08

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Significance: Extremity injury represents the leading cause of trauma hospitalizations among adults under the age of 65 years, and long-term impairments are often substantial. Restoring function depends, in large part, on bone and soft tissue healing. Thus, decisions around treatment strategy are based on assessment of the healing potential of injured bone and/or soft tissue. However, at the present, this assessment is based on subjective clinical clues and/or cadaveric studies without any objective measure. Optical imaging is an ideal method to solve several of these issues. Aim: The aim is to highlight the current challenges in assessing bone and tissue perfusion/viability and the potentially high impact applications for optical imaging in orthopaedic surgery. Approach: The prospective will review the current challenges faced by the orthopaedic surgeon and briefly discuss optical imaging tools that have been published. With this in mind, it will suggest key research areas that could be evolved to help make surgical assessments more objective and quantitative. Results: Orthopaedic surgical procedures should benefit from incorporation of methods to measure functional blood perfusion or tissue metabolism. The types of measurements though can vary in the depth of tissue sampled, with some being quite superficial and others sensing several millimeters into the tissue. Most of these intrasurgical imaging tools represent an ideal way to improve surgical treatment of orthopaedic injuries due to their inherent point-of-care use and their compatibility with real-time management. Conclusion: While there are several optical measurements to directly measure bone function, the choice of tools can determine also the signal strength and depth of sampling. For orthopaedic surgery, real-time data regarding bone and tissue perfusion should lead to more effective patient-specific management of common orthopaedic conditions, requiring deeper penetrance commonly seen with indocyanine green imaging. This will lower morbidity and result in decreased variability associated with how these conditions are managed.

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SPIE Journal Paper | 9 June 2020

Intraoperative fluorescence perfusion assessment should be corrected by a measured subject-specific arterial input function

Jonathan Elliott, Rocco Addante, Gerard Slobogean, Shudong Jiang, Eric Henderson, Brian Pogue, Ida Leah Gitajn

JBO Vol. 25 Issue 06

KEYWORDS: Luminescence, Tissues, Targeting Task Performance metric, Skin, Bone, Brain, Error analysis, Angiography, Surgery, Densitometry

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Proceedings Article | 19 February 2020 Presentation + Paper

Endosteal and periosteal blood flow quantified with dynamic contrast-enhanced fluorescence to guide open orthopaedic surgery

Shudong Jiang, Jonathan Elliott, Jason Gunn, Cao Xu, Alberto Ruiz, Brian Pogue, Eric Henderson, I. Leah Gitajn

Proc. SPIE. 11222, Molecular-Guided Surgery: Molecules, Devices, and Applications VI

KEYWORDS: Injuries, Tissues, Surgery, Imaging systems, Blood, Video, Luminescence, Indocyanine green, Bone, Blood circulation

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